ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Clinical Presentation and Outcomes of Transplant Glomerulopathy in Hepatitis C Positive Compared to Hepatitis C Negative Patients after Renal Transplantation

    S. Alexandru, A. Sevillano, L. Garcia-Puente, I. Bengoa, E. Gonzalez, M. Serrano, J. Martinez-Flores, A. Serrano, A. Andres, M. Martinez, J. Morales

    Nephrology, 12 de Octubre Universitary Hospital. Instituto de Investigación, Madrid, Spain; Immunology, 12 de Octubre Universitary Hospital. Instituto de Investigación, Madrid, Spain; Pathology, 12 de Octubre Universitary Hospital. Instituto de Investigación, Madrid, Spain

    It has been recently reported that transplant glomerulopathy (TG) is a pattern of pathological injury. Also, hepatitis C virus infection (HCV) has been associated with…
  • 2013 American Transplant Congress

    BK Polyoma Virus Infection and Efficacy of Leflunomide in Pediatric Renal Transplant Recipients

    B. Crowther, R. Hall, M. Arar, D. Ranch

    CHRISTUS Transplant Institute, CHRISTUS Santa Rosa, San Antonio, TX; Pediatrics, UTHSCSA, San Antonio, TX; University of Texas at Austin College of Pharmacy, Austin, TX; University Health System, San Antonio, TX; PERC, UTHSCSA, San Antonio, TX

    Purpose: To characterize BK virus infection and assess the efficacy of treatment strategies in pediatric renal transplant recipients.Methods: Retrospective chart review of renal transplant patients…
  • 2013 American Transplant Congress

    Flt3 Ligand Induces STAT3-Independent Expansion and Activation of Myeloid-Derived Suppressor Cells Able To Promote Heart Allograft Survival

    B. Rosborough, Q. Liu, D. Raich-Regue, B. Matta, L. Mathews, A. Thomson, H. Turnquist

    Surgery, Starzl Transplant Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA

    Introduction: Fms-like tyrosine kinase 3 ligand (Flt3L) is essential for myeloid cell homeostasis, particularly dendritic cells (DC), and acts through STAT3 to promote DC expansion.…
  • 2013 American Transplant Congress

    Screening for Inherited and Acquired Thrombophilia Prior to Renal Transplantation

    R. Silva, C. Moraes, I. Marques, F. de Paula, E. David-Neto

    Nephrology Division, University of Sao Paulo School of Medicine, Sao Paulo, Brazil; Renal Transplant Service, University of Sao Paulo School of Medicine, Sao Paulo, Brazil

    All patients with a history of a thromboembolic event, early or recurrent vascular access thrombosis, family history of thrombosis, or multiple miscarriages underwent laboratory screening…
  • 2013 American Transplant Congress

    Comparison of Baseline and Day 28 Post Transplant Renal Allograft Samples from the CTOT-10 Belatacept Study

    Y. Suessmuth, L. Stempora, B. Johnson, J. Cheeseman, Y. Morrison, N. Bridges, D. Ikle, S. Tomlanovich, P. Stock, R. Mannon, K. Newell, C. Larsen, A. Mehta

    Emory Transplant Center, Atlanta; Univ of Alabama-Birmingham, Birmingham; Univ of California San Francisco, San Francisco; NIAID/NIH, Bethesda; Rho, Chapel Hill, NC

    The purpose of the CTOT-10 study is to evaluate belatacept as maintenance therapy, while minimizing calcineurin inhibitors and corticosteroids in renal transplantation. We designed mechanistic…
  • 2013 American Transplant Congress

    Rationale for, and the Economic Implications Associated with, Extending Medicare Coverage for Immunosuppressive Medications to Kidney Transplant Recipients Who Lack Insurance Coverage, The

    R. Evans

    United Network for the Recruitment of Transplantation Professionals, Rochester, MN

    Immunosuppressive medications are essential in preventing kidney transplant rejection. Continuous insurance coverage for outpatient immunosuppressive medications remains a major issue. The objective of this analysis…
  • 2013 American Transplant Congress

    Uniform Long-Term Graft Survival in a Clincial Trial of the Induction of Tolerance to Kidney Transplants

    J. Scandling, S. Busque, A. Shori, S. Dejbakhsh-Jones, J. Shizuru, R. Lowsky, C. Benike, E. Engleman, S. Strober

    Stanford University, Stanford, CA

    Purpose: Over the last 12 years we have studied the safety and efficacy of a clinical tolerance induction protocol using hematopoietic cell transplantation in combination…
  • 2013 American Transplant Congress

    Development of Hepatic Ischemia and Reperfusion Injury Is Independent of Myeloid Cell-Derived COX-2

    S. Duarte, H. Kato, T. Ishikawa, R. Busuttil, H. Herschman, A. Coito

    David Geffen School of Medicine UCLA, Los Angeles

    Cyclooxygenase-2 (COX-2) is a powerful mediator of hepatic ischemia/reperfusion injury (IRI). While COX-2 depletion significantly ameliorates liver IRI, COX-2 inhibitors present clinical limitations; Therefore, there…
  • 2013 American Transplant Congress

    Mechanical Trauma Can Reactivate an Alloimmune Response Against the Skin-Component in a Large Animal Vascularized Composite Allotransplantation (VCA) Model of Operational Tolerance

    J. Christensen, Z. Ibrahim, L. Wu, A. Leto Barone, G. Furtmuller, K. Sarhane, M. Al-Rakan, S. Schneeberger, J. Shores, S. Bonawitz, D. Cooney, J. Sacks, W. Lee, G. Brandacher

    Plastic and Reconstructive Surgery, Johns Hopkins University, Baltimore

    BACKGROUND: The skin component of Vascularized Composite Allografts (VCA) is unique since it is directly exposed to the environment. It thereby not only offers opportunities…
  • 2013 American Transplant Congress

    Mixed Acute Rejection: Comparison of Therapeutic Results with Anti-T Cell Antibody- and Proteasome Inhibitor-Based Regimens

    F. Paterno, B. Sadaka, A. Shields, R. Alloway, M. Cardi, J. Kremer, M. Cuffy, T. Diwan, E. Woodle

    University of Cincinnati; The Christ Hospital

    Background: Mixed acute rejection (MAR) has been defined as acute rejection consisting of both cellular and humoral components. No data exist regarding MAR treatment outcomes,…
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