2013 American Transplant Congress
Safety Issues Identified by Proactive Liver Transplant Safety Debriefing
BACKGROUND: Transplantation and, in particular, living donor liver transplantation (LDLT), involves complex systems and process of care that are particularly susceptible to medical errors and…2013 American Transplant Congress
Simultaneous Pancreas-Kidney Transplantation in Patients with End-Stage Nephropathy Due to Type 2 Diabetes Mellitus Gives Better Results When Compared to Kidney Transplants Alone
Objective: SPK in type 2 diabetes (T2DM) is performed by a few centers in selected patients. The purpose of the study was to compare patient…2013 American Transplant Congress
CD39 Regulates the Activation of Liver DC and Protects Against Liver Transplant Ischemic Reperfusion Injury
Background: ATP is an energy source stored in the cell cytosol. Once released into extracellular(e) space as a result of cell injury/death, eATP acts in…2013 American Transplant Congress
Novel Model of Antibody Mediated Rejection of Kidney Allografts in Rats, A
We have developed a new experimental model of acute ABMR, in which complete MHC mismatched kidneys are transplanted from Brown Norway rats (RT1n) into Lewis…2013 American Transplant Congress
Parent and Child Perceptions of Long Term Psychosocial Functioning at > 5 Years Post-Intestine Transplant (ITx)
With improved survival following pediatric ITx, evaluating psychosocial outcomes in the long term is essential. Aim: Describe psychosocial outcomes of long term survivors at >…2013 American Transplant Congress
SCD Kidneys Defined by Age, but Associated with ECD-Defining Comorbidities Result in Inferior Recipient Outcomes
The Transplant Institute, Henry Ford Hospital, Detroit, MI
Studies of Expanded Criteria Donor (ECD) kidney (K) transplantation confirm lower allograft survival compared to Standard Criteria Donor (SCD)and donor age has been strongly implicated…2013 American Transplant Congress
Impact of Prospective Monitoring for Donor Specific Antibodies on Renal Transplant Outcomes with Alemtuzumab Induction
MultiOrgan Transplant Program, William Beaumont Hospital, Royal Oak, MI
Alemtuzumab (AL) induction has been associated with an excess of antibody-mediated rejection (AMR). We initiated a steroid-free AL protocol in August 2009 with prospective monitoring…2013 American Transplant Congress
ATP-Competitive mTORC1 and 2 Inhibitors Are a Novel Class of Immunosuppressants That Suppress Allograft Rejection
Surgery, Starzl Transplant Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA
Introduction: The mammalian Target of Rapamycin (mTOR) is the active catalytic subunit of two mTOR-containing complexes mTOR complex (mTORC) 1 and mTORC2. mTORC1 is…2013 American Transplant Congress
NKp46 Expression Accelerates the Formation of the NK Cell Lytic Immune Synapse
Natural killer cells play an important role in first-line defense against tumor and virus-infected cells. Studies suggest NK cells have a dichotomous role in transplantation…2013 American Transplant Congress
Modified Technique of Auxiliary Partial Liver Transplantation in Rat for the Study of Liver Regeneration and Tissue Engineering In Vivo, A
Background:Organ engineering and regenerative medicine using decellularized liver scaffolds offer a promising solution to organ shortage. Auxiliary partial liver transplantation (APLT) in rat is considered…