ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Fish Oil Diet Overcomes Genetic Predisposition Restoring Hepatocyte Proliferation in Livers of A20 Heterozygous Mice Following Partial Hepatectomy

    C. Da Silva, P. Studer, E. Csizmadia, D. Minussi, K. Daniels, C. Ferran

    Surgery, Beth Israel Deaconess Medical Center - HMS, Boston, MA

    Increased free fatty acids (FA) metabolism following partial hepatectomy (PH) is required to meet energy demands of liver regeneration (LR). Impact of dietary lipid intake…
  • 2013 American Transplant Congress

    Interim Analysis of a Double-Blinded Placebo Controlled Trial of IVIG v. IVIG + Rituximab for Desensitization of Highly-HLA Sensitized (PRA >80%) (HS) Deceased Donor (DD) Candidates

    A. Vo, J. Choi, M. Lukovsky, M. Toyoda, S. Ge, J. Kahwaji, A. Peng, R. Villicana, R. Najjar, S. Jordan

    Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA; Transplant Immunology Laboratory, Cedars-Sinai Medical Center

    INTRODUCTION: Desensitization protocols (DES) for HS patients are primarily aimed at living-donor recipients. The efficacy of various DES is not established, especially for DD recipients.…
  • 2013 American Transplant Congress

    NK Depletion Reduces Murine Cytomegalovirus Induced Renal Allograft Injury Despite Increased Viral Loads in a Murine Transplant Model

    M. Shimamura, L. Guo, J. George, T. Schoeb, W. Britt

    Pediatric Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL; Cardiovascular/Thoracic Surgery, University of Alabama at Birmingham, Birmingham, AL; Genetics, University of Alabama at Birmingham, Birmingham, AL

    PURPOSE: NK cell activation is induced by viral infection and has been associated with renal allograft injury in clinical populations and animal models, so this…
  • 2013 American Transplant Congress

    Long-Term Impact of a Pancreas Graft on a Previously Transplanted Kidney

    A. Gruessner, R. Gruessner

    College of Public Health, University of Arizona, Tucson, AZ; Department of Surgery, University of Arizona, Tucson, AZ

    Introduction]: While pancreas after kidney (PAK) transplant allow for pre-emptive kidney transplant and reduced waiting times, there is concern that the additional ‘burden' of the…
  • 2013 American Transplant Congress

    Humoral Rejection of Human Kidney Grafts Associates with Polyreactive Antibodies That Bind Apoptotic Cells and Activate Complement

    F. Porcheray, J. Fraser, B. Gao, A. McColl, J. DeVito, I. Dargon, Y. Helou, W. Wong, T. Girouard, S. Saidman, R. Colvin, A. Palmisano, U. Maggiore, A. Vaglio, R. Smith, E. Zorn

    Massachusetts General Hospital, Boston; University Hospital of Parma, Parma, Italy

    Antibody Mediated Rejection (AMR) is associated with a variety of graft-reactive antibodies following kidney transplant. To characterize these antibodies, we immortalized 107 B cell clones…
  • 2013 American Transplant Congress

    Preliminary Psychometric Properties of a Measure of the Allocation of Responsibility for Health Management Tasks in Pediatric Liver Transplant Recipients

    J. Bilhartz, M. Lopez, J. Magee, V. Shieck, S. Eder, R. Gleit, E. Fredericks

    University of Michigan, Ann Arbor, MI

    Purpose: The shift in responsibility for health-related tasks from parents to adolescents is essential to the transition to adult care. This study reports the preliminary…
  • 2013 American Transplant Congress

    Clinical Outcomes of Paired Kidney Exchange for Highly Sensitized Renal Transplant Recipients

    M. Grafals, M. Cooper, J. Verbesey, J. Vucci, B. Javaid, O. Timofeeva, S. Rosen-Bronson

    Georgetown Transplant Institute, Georgetown University Hospital, Washington, DC; Histocompatibility Laboratory, Georgetown University Hospital, Washington, DC

    Purpose: A local multicenter paired kidney exchange (PKE) was employed to facilitate identification of compatible donors for highly-sensitized recipients.Methods: Virtual crossmatching was used to identify…
  • 2013 American Transplant Congress

    Donor Brain Death Results in Differentially Modulated Immune Activation in Solid Organs

    P. Ritschl, R. Oberhuber, C. Fabritius, S. Ebner, B. Flörchinger, J. Guenther, A. Nguyen, J. Pratschke, K. Kotsch

    Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria; Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany

    Donor brain death (BD) and its pathophysiological changes have been shown to influence graft quality, therefore accelerating the immune response post transplantation. However, detailed information…
  • 2013 American Transplant Congress

    Associations between Clinical, Biochemical Indicators and Anthropometric Measurements with Arterial Stiffness in Renal Transplantation Patients

    M. Erkmen Uyar, E. Tutal, Z. Bal, B. Gurlek Demirci, O. Guliyev, E. Hasdemir, T. Colak, F. Ozdemir Acar, S. Sezer, M. Haberal

    Department of Nephrology, Baskent University, Ankara, Turkey; Department of Internal Medicine, Baskent University, Ankara, Turkey; Department of Nephrology, Baskent University, Istanbul, Turkey; Department of General and Transplantation Surgery, Baskent University, Ankara, Turkey

    Purpose: Arterial stiffness is an independent predictor for cardiovascular mortality. In end stage renal disease cardiovascular risk factors such as age, hypertension and diabetes mellitus…
  • 2013 American Transplant Congress

    D-MELD, a Powerful Instrument To Optimize Donor-2-Recipient Match. Differences between US and Italy

    A. Avolio, J. Halldorson, M. Lirosi, S. Agnes, M. Salizzoni, A. Pinna, M. Spada, L. De Carlis, M. Colledan, G. Gerunda, E. Andorno, G. Rossi, G. Ettorre, A. Risaliti, V. Mazzaferro, M. Rossi, G. Tisone, F. Zamboni, M. Vivarelli, L. Lupo, O. Cuomo, F. Calise, N. Nicolotti, A. Vitale, R. Romagnoli, A. Cucchetti, P. Bonsignore, I. Mangoni, D. Pinelli, R. Montalti, L. Caccamo, G. Vennarecci, D. Nicolini, E. Regalia, U. Baccarani, Q. Lai, T. Manzia, E. Tondolo, M. Rendina, A. Perrella, W. Santaniello, G. Bottino, G. Spagnoletti, G. Mariano, A. Gasbarrini, P. Burra, U. Cillo, the Donor-to-Recipient Italian Liver Transplant (DR2-ILTx) Study Group, Liver Transplant Centers

    Div. of Organ's Transplantation, Catholic University, Rome; , UCSD; , Turin; , Bologna; , Palermo; , Milan; , Bergamo; , Modena; , Genua; , Ancona; , Udine; , Cagliari; , Bari; , Naples; , Padua

    Previous studies demonstrated in US and Italy that D-MELD can be an instrument to optimize donor-2-recipient match (D2Rm) in Liver Transplantation.To characterize prognostic power, peculiarities…
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