2013 American Transplant Congress
Outcomes of Intestine Transplantation in an Underserved Urban Community
Background: Isolated intestinal transplant (ITx) is indicated for patients with irreversible intestinal failure requiring parenteral nutrition with complications. Multivisceral transplant (MVTx) is reserved for patients…2013 American Transplant Congress
Prospective Analysis of CD19dimCD27highCD20neg Blood Plasma Cells in Renal Transplant Patients after Combined Treatment with Rituximab and Bortezomib in Antibody Mediated Rejection
Nephrology, Charité Universitätsmedizin, Berlin, Germany
Treatment of antibody-mediated rejection (AMR) in renal transplant (Tx) patients (pts) is still challenging and long-term outcomes remain poor. Because plasma cells (PCs) are crucial…2013 American Transplant Congress
Knockdown of Intra-Islet IKKβ by Spherical Nucleic Acid Nanoparticle Conjugates Prevents Host Cytokine-Induced Injury and Enhances Islet Graft Survival
Islet transplantation is a challenging treatment for type-1 diabetic patients. This is due, in part, to the deleterious effects of pro-inflammatory cytokines generated by early…2013 American Transplant Congress
Pigs Deficient in N-Glycolylneuraminic Acid and Galactose α-1,3-Galactose Reduce the Humoral Barrier to Xenotransplantation
Transplant Surgery, Indiana University School of Medicine, Indianapolis, IN
Hyperacute rejection of porcine xenografts in a non-human primate model has been diminished with development of Α1,3-galactosyltransferase knockout (GT-KO) pigs devoid of the galactose Α-1,3-galactose…2013 American Transplant Congress
Pharmaceutical Quality and Bioequivalence Assessment of Generic Mycophenolate Mofetil Tablets
Office of Generic Drugs, FDA, Rockville
Purpose. Mycophenolate Mofetil (MMF) is the most used immunosuppressant in solid organ transplantation. Concerns have been raised about substitution between brand and generic MMF tablets.…2013 American Transplant Congress
Banff Scoring in Early and Late Acute Cellular Rejection Predicts Graft Survival
U of Cincinnati, Cincinnati, OH; Christ Hospital, Cincinnati, OH
Acute rejection (AR) Banff grade (BG) correlates with long-term graft survival, however, previous validation studies did not account for rejection type (acute cellular rejection (ACR)/antibody…2013 American Transplant Congress
Depletion of Both Recipient and Donor Foxp3+ Cells Can Break Tolerance of Skin or Heart Allografts Induced by Mixed Chimerism in Mice
Donor-specific transplant tolerance has been achieved by induction of mixed chimerism in both mice and humans and evidence for both deletion and regulation exists. To…2013 American Transplant Congress
Is Micro-RNA-122 (miR-122) an Accurate Biomarker for Ischemia-Reperfusion Injury during Liver Transplantation?
PURPOSE: Liver specific miR-122 has been shown to be potential biomarker for liver injury; however initial production of miR-122 during allograft reperfusion has not been…2013 American Transplant Congress
Significant Deficiencies in Postoperative Handoffs Revealed in a Comprehensive Assessment of Living Donor Liver Transplantation Systems and Processes of Care
Purpose: To identify failures in the handoff from the OR to the intensive care unit (ICU) of living donor liver transplant (LDLT) that lead to…2013 American Transplant Congress
Implications of the Statewide Sharing Variance on Kidney Transplantation Geographic Inequity and Allocation Efficiency
Purpose: The Statewide Sharing (SS) local allocation variance offers non-locally allocated kidneys to patients listed in other Donor Service Areas (DSA) within the state of…
American Transplant Congress abstracts