2013 American Transplant Congress
Long-Term Satisfaction with Life after Living Kidney Donation: A RELIVE Study
Background:Little is known about the long-term satisfaction with life (SWL) of live kidney donors. We surveyed SWL among a population of kidney donors participating in…2013 American Transplant Congress
Probability of a Positive AHG-CDC Crossmatch Is Determined by the Number, Strength, and Specificity of Donor-Specific Antibodies
Background: The factors determining the relationship between donor-specific antibodies (DSA) and the anti-human globulin complement-dependent cytotoxicity crossmatch (AHG-CDC XM) are not clearly defined. Canadian consensus…2013 American Transplant Congress
Recipient Death and Graft Loss in Renal Transplantation: The Challenge of Infectious Complications
Hospital do Rim e Hipertensão, Sao Paulo, Brazil
Introduction: The causes of recipient death and renal allograft loss are still under evaluated, and there might be several differences according to the era of…2013 American Transplant Congress
IL-33 Expands ST2+ Regulatory T Cells Promoting Allograft Survival Directly and Indirectly through Actions on Myeloid Dendritic Cells
Background: IL-33 is an IL-1 cytokine that signals via ST2, which is expressed on both T cells and myeloid cells. IL-33 has been ascribed Th2…2013 American Transplant Congress
Results of a Phase 2 Safety, Efficacy, and Pharmacokinetic Study of TOL-101, an Anti-TCR Monoclonal Antibody for the Prophylaxis of Acute Rejection in Kidney Transplantation
Purpose: Induction therapy using anti-lymphocytic antibodies is a potent tool for the prevention of early rejection after kidney transplantation. TOL-101, an IgM monoclonal antibody, with…2013 American Transplant Congress
Thrombin Generation and Platelet Activation in a Xenogenic Lung Perfusion Model Determine Survival of GalTKO.hCD46 Transgenic Lungs
Surgery, University of Maryland, Baltimore, MD; Revivicor, Inc., Blacksburg, VA
Purpose: As previously reported, the development of GalTKO pigs with additional expression of hCD46 has contributed to a significantly improved outcome of lungs in an…2013 American Transplant Congress
Blocking C3a/C5a-Receptor Signaling Promotes Induction and Stability of Murine and Human Alloreactive Regulatory T Cells
Immunology Institute, Mount Sinai School of Medicine, New York, NY
Adoptive transfer of CD4+Foxp3+ regulatory T cells (Treg) has potential for promoting transplantation tolerance but is limited by the scarcity of thymic-derived Treg and the…2013 American Transplant Congress
Abnormal Distribution of B-Cell Populations Associated with Impaired Regulatory Functions in Chronic Antibody Mediated Rejection
Chronic antibody (Ab) mediated rejection (cAMR) represents the major problem in renal transplantation. The aim of our study was to analyze B lymphocyte (LB) distribution…2013 American Transplant Congress
Update on Phase 2 Clinical Trial To Induce Tolerance in Mismatched Living Donor Renal Transplant Recipients
19 subjects have been enrolled in a phase 2 protocol (FDA IDE 13947) to induce tolerance in mismatched recipients of living donor renal allografts (KTx).…2013 American Transplant Congress
Product of Donor Age and Preoperative MELD, D−MELD, Predicts Surgical Outcomes after LDLT in HCV Positive Recipients, but Not in HCV Negative Recipients, The
Background:Donor age and MELD score are recognized as risk factors affecting recipient outcomes in living donor liver transplantation (LDLT). The aim of this study is…
American Transplant Congress abstracts