Abstracts Archive - Page 157 of 1683 - ATC Abstracts

2022 American Transplant Congress
Exosomal TGFbeta:LAP as Immunosuppressive Mediator of Allo-Tolerance
W. Burlingham¹, E. Jankowska-Gan², J. Fechner³, C. Little², J. Sullivan⁴, D. Foley¹
¹University of Wisconsin, Madison, WI, ²Surgery-Transplant Division, University of Wisconsin, Madison, WI, ³Surgery-Transplant Division, University of Wisconsin-Madison, Madison, WI, ⁴Surgery, University of Wisconsin, Madison, WI
*Purpose: TGFβ has long been known as a key component in tolerance mediated by Treg cells. Here we show that, unlike IL10, but like CD39/CD73,…
2022 American Transplant Congress
Bariatric Surgery and Alcohol Related Steatohepatitis (BASH): An Increasing Etiology in Pre-Liver Transplant Candidates
S. Nishida¹, K. Okumura¹, A. Dhand², R. Bodin², S. Yaghoubian³, C. Greenberg¹, R. Misawa¹, G. Veillette¹, H. Sogawa¹, D. John¹, D. C. Wolf², B. Partiula², T. Diflo¹, R. Latifi¹, S. Lansman¹
¹Surgery, Westchester Medical Center/ New York Medical College, Valhalla, NY, ²Medicine, Westchester Medical Center/ New York Medical College, Valhalla, NY, ³Anesthesia, Westchester Medical Center/ New York Medical College, Valhalla, NY
*Purpose: Obesity-related fatty liver disease and non-alcoholic steatohepatitis (NASH) are common causes of End-stage liver disease (ESLD). Bariatric surgery (BS) is commonly indicated for these…
2022 American Transplant Congress
Collaboration for Successful Transition to Adult Care in Liver Transplant: Early Outcomes of a Structured Program with Youth Engagement
B. Kosmach-Park¹, J. Kilpatrick², A. Algeo¹, K. Jones¹, L. Remaley¹, N. Elazzazy², N. Jonassaint³, G. Mazariegos¹
¹Transplant Surgery, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, ²Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, ³Department of Medicine and Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA
*Purpose: To effectively transition youth to adult hepatology through a structured program and developed partnerships while promoting and maintaining optimal outcomes.*Methods: The pediatric and adult…
2022 American Transplant Congress
Significant Improvements, but Consistent Disparities in Survival for African Americans After Liver Transplantation
S. S. Keeling
Baylor College of Medicine, Houston, TX
*Purpose: Despite improvements in survival for all races in the past twenty years, African American patients have worse liver transplant outcomes after undergoing orthotopic liver…
2022 American Transplant Congress
Circulating and Intragraft Donor (HLA)-Specific B Cells Drive Allograft Rejection After Kidney Transplantation
A. Torija¹, N. Bolaños¹, L. Donadeu¹, M. Meneghini², I. Torres², A. Gabaldon², M. Gomà³, E. Crespo¹, F. Moreso⁴, O. Bestard²
¹Vall d'Hebron Research Institute (VHIR), Barcelona, Spain, ²Vall d'Hebron University Hospital, Barcelona, Spain, ³Bellvitge University Hospital, Barcelona, Spain, ⁴Vall d'Heron University Hospital, Barcelona, Spain
*Purpose: Besides donor-specific antibodies (DSA), circulating donor(HLA)-specific memory B cells (mBc) have also shown to play a deleterious role driving antibody-mediated rejection (ABMR) in kidney…
2022 American Transplant Congress
A Single Center Experience of Simultaneous Heart-Kidney Transplantation
A. Samra¹, A. Mattoo²
¹Nephrology, New York University Langone Transplant Institute, New York, NY, ²New York University Langone Transplant Institute, New York, NY
*Purpose: Currently there are no UNOS guidelines regarding the selection criteria required for simultaneous heart-kidney transplant recipients (SHKT). As of 2018 our center has begun…
2022 American Transplant Congress
Understanding the Heterogeneity of Alloreactive Natural Killer (NK) Cell Function in Kidney Transplant Recipients
D. Ruan, M. Fribourg, N. Chun, P. Cravedi, A. Horowitz, P. Heeger
Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: Emerging evidence indicates that human NK cells are a heterogeneous population of lymphocytes that are activated upon ligation of one or more activating receptors…
2022 American Transplant Congress
Analysis of Induction Dose and Incidence of CMV Viremia in High Risk (HR; D+/R-) Renal Transplant Recipients
K. Shimko, M. Pittappilly, R. Chowdhury, H. Karimi, C. Puttarajappa, M. Wijkstrom, R. Mehta
University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: Depleting induction puts patients at risk of opportunistic infections. Our protocol aims for 5-6mg/kg cumulative dose of antithymocyte globulin(ATG) divided over 4 doses. It…
2022 American Transplant Congress
Daratumumab for Recurrence of Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits in a Post-Kidney Transplant Recipient: A Case Report
K. Progar¹, T. Alhamad², H. Murad³, A. Java⁴, A. Malone⁵, J. Gaut⁶, R. Delos Santos⁷, M. Merzkani⁸
¹Transplant, Barnes-Jewish Hospital, St. Louis, MO, ²Washington University School of Medicine at St. Louis, Saint Louis, MO, ³Transplant, Washington University, St. Louis, MO, ⁴Washington University School of Medicine in St. Louis, Saint Louis, MO, ⁵Washington University School of Medicine, Saint Louis, MO, ⁶Washington University, Saint Louis, MO, ⁷Transplant Nephrology, Washington University School of Medicine, St. Louis, MO, ⁸Transplant, Washington University School of Medicine, Saint Louis, MO
*Purpose: Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits (PGNMID) is a rare kidney disease associated with a high rate of recurrence post-kidney transplantation resulting in graft…
2022 American Transplant Congress
Survival Benefit of Preemptive Simultaneous Pancreas Kidney Transplantation
E. Montagud-Marrahi¹, E. Cuadrado-Payán¹, E. Hermida¹, D. Cucchiari¹, I. Revuelta¹, J. Del Risco-Zevallos¹, J. Casals¹, N. Esforzado¹, F. Cofan¹, F. Oppenheimer¹, V. Torregrosa¹, J. Ferrer², A. J. Amor³, E. Esmatjes¹, M. Ramirez-Bajo⁴, M. Musquera⁵, B. Bayés¹, J. Campistol¹, F. Diekmann¹, P. Ventura-Aguiar¹
¹Nephrology and Kidney Transplantation Department, Hospital Clínic of Barcelona, Barcelona, Spain, ²Hepatobiliopancreatic and Liver Transplant Department, Hospital Clínic of Barcelona, Barcelona, Spain, ³Diabetes Unit. Endocrinology and Nutrition Department, Hospital Clínic of Barcelona, Barcelona, Spain, ⁴Laboratori Experimental de Nefrologia I Trasplantament (LENIT), Fundació Clínic per a la Recerca, Hospital Clínic of Barcelona, Barcelona, Spain, ⁵Urology Department, Hospital Clínic of Barcelona, Barcelona, Spain
*Purpose: Diabetes mellitus is a well-established risk factor for morbidity and mortality among patients on dialysis, but the evidence regarding the benefits of performing preemptive…