ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Endothelial-to-Mesenchymal Transition Contributes to Cardiac Allograft Rejection and Vasculopathy

    Y. Xiao, Z. Mao, H. Liu

    Thoracic, Renmin Hospital of Wuhan University, Wuhan, Hubei, China; Surgery, Children' Hospital, Boston, MA

    The chronic allograft rejection, i.e. transplant vasculopathy (TV), is a major limiting factor in the long-term success of cardiac transplantation. In the present study, we…
  • 2013 American Transplant Congress

    Kidney-Induced Cardiac Allograft Tolerance across a Full MHC-Barrier in Miniature Swine

    M. Madariaga, S. Michel, M. Tasaki, V. Villani, E. Farkash, G. La Muraglia II, J. Allan, D. Sachs, K. Yamada, J. Madsen

    Cardiothoracic Transplantation Laboratory, Transplantation Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA

    We have previously demonstrated that a kidney allograft has the ability to confer tolerance on a co-transplanted heart allograft procured from a class I-mismatched donor.…
  • 2013 American Transplant Congress

    Heat Shock Protein 90 Is Involved in Antibody-Mediated Rejection and Is a Potential Target of Anti-Rejection Therapy in Kidney Transplantation

    T. Tanaka, H. Ishida, M. Furusawa, Y. Tamura, H. Kitamura, S. Takahashi, N. Masumori, K. Tanabe, N. Sato, T. Tsukamoto

    Urology, Sapporo Medical University, Sapporo, Japan; Urology, Tokyo Women's Medical University, Tokyo, Japan; Pathology, Sapporo Medical University, Sapporo, Japan

    Purpose: Heat shock protein 90 (HSP90) is a ubiquitously expressed molecular chaperone that is associated with the correct activation of client proteins. Important roles of…
  • 2013 American Transplant Congress

    Probability of Deceased Donor Kidney Transplantation Based on PRA%

    I. Bostock, J. Alberu, A. Adriana, D. Adrian, G. Norma, L. Mayra, C. Natalia, M. Luis, G. Bernardo, V. Mario

    Transplantation Department, Instituto Nacional de Ciencias Medicas y Nutricion, Mexico City, Distrito Federal, Mexico; Histocompatibility Department, Instituto Nacional de Ciencias Medicas y Nutricion, Mexico City, Distrito Federal, Mexico

    Sensitization to HLA antigens creates an obstacle for the accessibility and success of kidney transplantation (KT). Highly sensitized patients have longer waiting times and some…
  • 2013 American Transplant Congress

    Role of Immunoglobulin (Ig)-G Subclasses and C1q in De Novo HLA DQ DSA Kidney Transplant Outcomes, The

    M. Freitas, L. Rebellato, M. Ozawa, A. Nguyen, M. Everly, N. Sasaki, P. Terasaki

    Terasaki Foundation Laboratory, Los Angeles, CA; One Lambda Inc, Canoga Park, CA; Department of Pathology, Brody School of Medicine at East Carolina University, Greenville, NC

    Background. Anti-HLA DQ antibodies are the predominant HLA class II donor-specific- antibodies (DSAs) after transplantation. Recently, de novo DQ DSA has been associated with worse…
  • 2013 American Transplant Congress

    Role of IV Acetaminophen (APAP) in Reducing Narcotic Use in Live Donor Nephrectomy, The

    M. Tan, T. Ommert, R. Cross, M. Mulloy, S. D'Annunzio, M. Johnson, H. Pollinger

    Piedmont Hospital, Atlanta

    INTRODUCTION: The proliferation of live donor kidney transplant is due in part to the application of minimally invasive surgical techniques. The introduction of robotics to…
  • 2013 American Transplant Congress

    Paired Kidney Analysis of Delayed Graft Function: Recipient Risk Factors for and Role in Graft Survival, A

    J. Malheiro, P. Aguiar, I. Fonseca, L. Martins, M. Almeida, S. Pedroso, L. Dias, A. Henriques, A. Cabrita

    Nephrology Unit, CH Porto, Porto, Portugal

    Delayed graft function (DGF) is a common complication of kidney transplantation related with both donor and recipient. Through a donor-paired kidney analysis we aimed to…
  • 2013 American Transplant Congress

    Should National Policymakers Augment Marginal Liver Transplants: A Population Game Approach

    Nephrology, LUMC, Leiden, Netherlands; Clinical Epidemiology, LUMC, Leiden, Netherlands; Einthoven Laboratory for Experimental Vascular Research, LUMC, Leiden, Netherlands; Surgery, LUMC, Leiden, Netherlands

    Purpose: Federal mandates have increased the availability of marginal livers for transplant despite worse outcomes. Yet the impact of augmenting marginal liver transplantation from the…
  • 2013 American Transplant Congress

    Vascularization Improvement and Rejection Protection in Rat Islet Transplantation by Endothelial Cells Coating and Sertoli Cells Coculture

    Y. Li, W. Xue, X. Tian, X. Ding, X. Feng, X. Wang, P. Tian, J. Zheng, C. Ding, X. Pan

    First Affiliated Hospital, Medical College, Xi'an Jiaotong University, Xi'an, China

    Backbrounds.Improving islet graft revascularization and inhibiting rejection become crucial tasks for prolonging islet graft survival. Endothelial cells (ECs) are the basis of islet vascularization and…
  • 2013 American Transplant Congress

    Cost-Effectiveness of Hand-Assisted Retroperitoneoscopic Versus Standard Laparoscopic Donor Nephrectomy: A Randomized Study

    K. Klop, N. Kok, S. Janki, L. Dols, F. d'Ancona, E. Adang, J. Grutters, J. IJzermans

    Department of Transplant Surgery, Erasmus University Medical Center, Rotterdam, Netherlands; Department of Urology, Radboud University Medical Center, Nijmegen, Netherlands; Department of Epidemiology, Biostatistics and HTA, Radboud University Medical Center, Nijmegen, Netherlands

    Background: Live kidney donation has a clear economical benefit over cadaveric transplantation and dialysis. When compared with mini-incision open donor nephrectomy, laparoscopic donor nephrectomy (LDN)…
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