ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Grading System for Micro-Vascular Invasion in Transplanted Hepatocellular Cancer, A

    N. Lubezky, H. Noboru, E. Silberman, P. Tabrizian, H. Ko, A. Harrington, J. Hernandez-Prera, M. Fiel, S. Thung, M. Schwartz, S. Roayaie

    Mount Sinai Liver Cancer Program, Mount Sinai Medical Center, New York, NY; The Lillian and Henry M. Stratton-Hans Popper Department of Pathology, Mount Sinai Medical Center, New York, NY

    Background & Aims: Microvascular invasion (mVI) has repeatedly been correlated with recurrence and survival after liver transplantation (OLT) for hepatocellular cancer (HCC). A grading system…
  • 2013 American Transplant Congress

    NFAT-Dependent Cytokine and p70S6 Kinase Activity Assays as Immune Monitoring Tools for Transplant Patients on CNIs and mTOR Inhibitors

    A. Webber, R. Hirose, C. Leung, F. Vincenti

    Kidney Transplant Service, UCSF, San Francisco, CA

    Objective: To compare NFAT-regulated gene expression and p70S6k activity in kidney transplant patients maintained on full-dose tacrolimus plus MPA versus reduced-dose tacrolimus and everolimus.Methods: Peripheral…
  • 2013 American Transplant Congress

    Economic and Clinical Consequences of ABO Incompatible Kidney Transplantation: A National Database Study, The

    C. Simpkins, K. Lentine, H. Xiao, M. Schnitzler, J. Tuttle-Newhall, D. Segev, V. Dharnidharka, D. Brennan, D. Axelrod

    Dartmouth Univ; Saint Louis Univ; Johns Hopkins Univ; Washington Univ

    ABO incompatible (ABOi) live donor kidney transplantation (LKDT) accompanied by plasmapheresis can offer a transplant option superior to continued waiting on dialysis. However, further expansion…
  • 2013 American Transplant Congress

    Racial Variation in Medical Outcomes among Medicare and Privately-Insured Living Kidney Donors

    K. Lentine, D. Segev, D. Axelrod, A. Garg, D. Brennan, J. Tuttle-Newhall, M. Schnitzler

    Saint Louis Univ; Johns Hopkins Univ; Dartmouth Univ; London Health Sci Centre; Washington Univ

    We examined a novel linkage of Organ Procurement and Transplant Network (OPTN) registry data for prior living kidney donors (LKDs) with Medicare billing claims to…
  • 2013 American Transplant Congress

    Dyslipidemia in the First Year after Renal Transplantation: Its Prevalence, Associated Clinical and Genomic Factors, and Graft Survival

    K. Numakura, S. Satoh, M. Saito, N. Komine, S. Akihama, T. Inoue, S. Narita, N. Tsuchiya, T. Habuchi

    Urology, Akita University Graduate School of Medicine, Akita, Japan; Renal Replacement Therapeutic Science, Akita University School of Medicine, Akita, Japan

    Introduction and Objective: Dyslipidemia is common among renal transplant recipients and may be a risk factor for cardiovascular disease and graft dysfunction. The present study…
  • 2013 American Transplant Congress

    Bone Marrow-Derived Mesenchymal Stem Cells of Neonatal Mice Suppress Dendritic Cells Maturation and T Lymphocyte Proliferation

    X. Dai, X. Li, J. Ma, J. Wang, N. Gong

    Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

    Background: Mouse bone marrow-derived mesenchymal stem cells (MSCs) cannot be easily harvested in matured mice because of the low MSC frequency, contamination of hematopoietic cells…
  • 2013 American Transplant Congress

    Impact of Immunosenescence on Bone Marrow Transplantation (BMT) and Chimerism, The

    K. Hock, R. Oberhuper, Y. Lee, T. Wekerle, S. Tullius

    Department of Surgery, Medical University of Vienna, Vienna, Austria; Division of Transplant Surgery and Transplant Surgery Research Lab, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Department of Visceral, Transplant and Thoracic Surgery, Innsbruck Medical University, Innsbruck, Austria

    Background:Tolerance induction through mixed chimerism holds promise for clinical translation but has only been investigated in young recipients. Changing demographics and an accumulation of older…
  • 2013 American Transplant Congress

    Donor CD4 T Cells Trigger Costimulation Blockade-Resistant Donor Bone Marrow Rejection through Bystander Activation Requiring Interleukin 6

    K. Hock, N. Pilat, U. Baranyi, B. Mahr, C. Klaus, M. Gattringer, T. Wekerle

    Division of Transplantation, Department of Surgery, Medical University of Vienna, Vienna, Austria

    Background:Donor T cells have pleiotropic effects in allogeneic bone marrow transplantation (BMT). Co-transplanting high doses of donor T cells with donor BM causes rejection of…
  • 2013 American Transplant Congress

    Epigenetic Analysis of the TSDR of FOXP3 Demonstrates That Natural Treg Infiltrate the Cardiac Allograft Already before an Acute Rejection Episode

    K. Boer, A. Peeters, A. Maat, K. Caliskan, A. Balk, W. Weimar, C. Baan

    Internal Medicine, Erasmus University Medical Center, Rotterdam, Netherlands; Thoracic Surgery, Erasmus University Medical Center, Rotterdam, Netherlands; Cardiology, Erasmus University Medical Center, Rotterdam, Netherlands

    IntroductionTwo subtypes of FOXP3+ regulatory T cells (Treg) have been identified. Natural (n) Treg originate in the thymus, while antigen specific induced (i) Treg are…
  • 2013 American Transplant Congress

    Natural History of the Arteriovenous Access and Risk Factors Affecting Spontaneous Closure after Successful Kidney Transplantation, The

    J. Kim, J. Hwang, S. Park, C. Yang, I. Moon

    Surgery, The Catholic University of Korea, Seoul, Republic of Korea; Internal Medicine, The Catholic University of Korea, Seoul, Republic of Korea

    Purpose; After successful kidney transplantation (KT), arteriovenous access (AVA) is neither used nor useful. There are many debates whether to preserve an AVA or to…
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