2013 American Transplant Congress
Grading System for Micro-Vascular Invasion in Transplanted Hepatocellular Cancer, A
Background & Aims: Microvascular invasion (mVI) has repeatedly been correlated with recurrence and survival after liver transplantation (OLT) for hepatocellular cancer (HCC). A grading system…2013 American Transplant Congress
NFAT-Dependent Cytokine and p70S6 Kinase Activity Assays as Immune Monitoring Tools for Transplant Patients on CNIs and mTOR Inhibitors
Kidney Transplant Service, UCSF, San Francisco, CA
Objective: To compare NFAT-regulated gene expression and p70S6k activity in kidney transplant patients maintained on full-dose tacrolimus plus MPA versus reduced-dose tacrolimus and everolimus.Methods: Peripheral…2013 American Transplant Congress
Economic and Clinical Consequences of ABO Incompatible Kidney Transplantation: A National Database Study, The
Dartmouth Univ; Saint Louis Univ; Johns Hopkins Univ; Washington Univ
ABO incompatible (ABOi) live donor kidney transplantation (LKDT) accompanied by plasmapheresis can offer a transplant option superior to continued waiting on dialysis. However, further expansion…2013 American Transplant Congress
Racial Variation in Medical Outcomes among Medicare and Privately-Insured Living Kidney Donors
Saint Louis Univ; Johns Hopkins Univ; Dartmouth Univ; London Health Sci Centre; Washington Univ
We examined a novel linkage of Organ Procurement and Transplant Network (OPTN) registry data for prior living kidney donors (LKDs) with Medicare billing claims to…2013 American Transplant Congress
Dyslipidemia in the First Year after Renal Transplantation: Its Prevalence, Associated Clinical and Genomic Factors, and Graft Survival
Introduction and Objective: Dyslipidemia is common among renal transplant recipients and may be a risk factor for cardiovascular disease and graft dysfunction. The present study…2013 American Transplant Congress
Bone Marrow-Derived Mesenchymal Stem Cells of Neonatal Mice Suppress Dendritic Cells Maturation and T Lymphocyte Proliferation
Background: Mouse bone marrow-derived mesenchymal stem cells (MSCs) cannot be easily harvested in matured mice because of the low MSC frequency, contamination of hematopoietic cells…2013 American Transplant Congress
Impact of Immunosenescence on Bone Marrow Transplantation (BMT) and Chimerism, The
Background:Tolerance induction through mixed chimerism holds promise for clinical translation but has only been investigated in young recipients. Changing demographics and an accumulation of older…2013 American Transplant Congress
Donor CD4 T Cells Trigger Costimulation Blockade-Resistant Donor Bone Marrow Rejection through Bystander Activation Requiring Interleukin 6
Division of Transplantation, Department of Surgery, Medical University of Vienna, Vienna, Austria
Background:Donor T cells have pleiotropic effects in allogeneic bone marrow transplantation (BMT). Co-transplanting high doses of donor T cells with donor BM causes rejection of…2013 American Transplant Congress
Epigenetic Analysis of the TSDR of FOXP3 Demonstrates That Natural Treg Infiltrate the Cardiac Allograft Already before an Acute Rejection Episode
IntroductionTwo subtypes of FOXP3+ regulatory T cells (Treg) have been identified. Natural (n) Treg originate in the thymus, while antigen specific induced (i) Treg are…2013 American Transplant Congress
Natural History of the Arteriovenous Access and Risk Factors Affecting Spontaneous Closure after Successful Kidney Transplantation, The
Purpose; After successful kidney transplantation (KT), arteriovenous access (AVA) is neither used nor useful. There are many debates whether to preserve an AVA or to…