ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Prospective Surveillance of Kidney Transplant Recipients for BK Viremia Can Reduce or Eliminate BK Virus Associated Nephropathy (BKVAN) Related Graft Loss: Results of a 5-Year Screening Study

    N. Elfadawy, S. Flechner, X. Liu, J. Schold, R. Fatica, T. Srinivas, E. Poggio, R. Avery, S. Mossad

    Glickman Urological and Kidney Institute, Cleveland Clinic Foundation, Cleveland, OH; Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH; Infectious Disease/Medicine Institute, Cleveland Clinic, Cleveland, OH

    Purpose: We aimed to identify the incidence and risk factors for BKVAN as well as measure the impact of immediate therapy on the graft and…
  • 2013 American Transplant Congress

    Efficacy and Safety of Corticosteroid Withdrawal (CSW) in Kidney Transplant Recipients during Routine Practice: A Prospective, 4-Year Analysis from the Mycophenolic Acid Observational Renal Transplant (MORE) Study

    K. Ueda, A. Wiland, K. McCague, V. Ram Peddi

    California Pacific Medical Center, San Francisco, CA; Novartis Pharmaceuticals Corporation, East Hanover, NJ

    Prospective, long-term data on efficacy and safety outcomes following CSW versus corticosteroid continuation (CSC) in kidney transplant patients during routine clinical practice are largely unavailable.Methods:…
  • 2013 American Transplant Congress

    Intracoronary Treatment with VEGF-C/D Inhibitor Enhances Cardiac Allograft Survival and Prevents Chronic Rejection by Regulating Lymphatic Endothelial Cell Activation

    A. Dashkevich, S. Syrjälä, M. Keränen, R. Tuuminen, R. Krebs, N. Antti, K. Alitalo, K. Lemström

    Transplantation Laboratory, Haartman Institute, University of Helsinki, Helsinki, Finland; Department of Cardiothoracic Surgery, Helsinki University Hospital, Helsinki, Finland; Molecular/Cancer Biology Program, Institute for Molecular Medicine Finland, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland

    Purpose: VEGF-C/D/VEGFR-3 signaling may regulate lymphatic vessel activation and the initiation of alloimmunity after transplantation. However, the mechanisms remain unknown. We investigated the effect of…
  • 2013 American Transplant Congress

    Death on Wating-List and Risk of Transmission of Cancer: Where Is the Right Balance?

    R. Desai, D. Collett, C. Watson, P. Johnson, T. Evans, J. Neuberger

    NHS Blood and Transplant, Bristol, United Kingdom; Addenbrooke's Hospital, Cambridge, United Kingdom; University of Birmingham, Birmingham, United Kingdom; West Midlands Cancer Intelligence Unit, Birmingham, United Kingdom

    Cancer transmission from organ donors is a rare complication of transplantation. While some cancer histories in donors are classed as unacceptable or high risk because…
  • 2013 American Transplant Congress

    Understanding Transplant Education Practices in Dialysis Centers: Comparing Dialysis Educator and Medicare Patient Data

    A. Waterman, J. Peipert, H. Xiao, C. Goalby, E. Herrington, S. Munigala, K. Dinkel, K. Lentine

    Washington University School of Medicine, St. Louis, MO; Center for Outcomes Research, St. Louis University, St. Louis, MO; Heartland Kidney Network, Kansas City, MO

    The Centers for Medicare and Medicaid Services’ (CMS) mandates that dialysis centers inform patients of their transplant options and report progress of this within 45…
  • 2013 American Transplant Congress

    HLA Class I Antibody Augments FGF-23 Induced Transplant Vasculopathy and Chronic Antibody Mediated Rejection

    E. Tsai, Y. Jin, K. Wesseling-Perry, I. Salusky, R. Ettenger, E. Reed

    Pediatric Nephrology, UCLA, Los Angeles, CA; Pathology and Laboratory Medicine, UCLA, Los Angeles, CA

    Background: Fibroblast growth factor 23 (FGF-23), which binds to FGF receptor, has been associated with allograft rejection, CKD progression, and poor graft survival in pediatric…
  • 2013 American Transplant Congress

    Tacrolimus Is More Than Just a Calcineurin Inhibitor: It Suppresses NF-κB Activation in Human T Cells

    R. Vafadari, R. Kraaijeveld, W. Weimar, C. Baan

    Internal Medicine, Erasmus MC, Rotterdam, Netherlands

    Background: The calcineurin-inhibitor, tacrolimus (TAC), inhibits the protein-phosphatase-activity of calcineurin, leading to suppression of the nuclear translocation of NFAT and subsequent T-cell activation. Apart from…
  • 2013 American Transplant Congress

    Protective Effect and Mechanism of NKA DR Region Specific Antibody on Ischemia-Reperfusion-Induced Renal Injury in Rats

    J. Zheng, W. Xue, P. Tian, X. Ding, H. Yan, J. Hou, X. Tian, Y. Li, C. Ding

    Hospital of Nephrology, The First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an, China

    Background: Renal ischemia reperfusion (I/R) injury is the main factors to affect the early functional recovery and the long-term survival of transplanted kidney in renal…
  • 2013 American Transplant Congress

    Anchoring Heparin to the Surface of Islet Improved Revascularization in Islet Transplantation

    X. Tian, Y. Li, H. Song, X. Ding, X. Feng, J. Hou, W. Xue, P. Tian

    The Department of Renal Transplantation, The First Affiliated Hospital, Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi, China; The Department of Osteology, The Second Affiliated Hospital, Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi, China

    Objective: We all know that the inadequate blood supply is likely contributors to islet death in the immediate posttransplant period and may impair islet survival…
  • 2013 American Transplant Congress

    Does the Abnormal Result of Implantation Renal Biopsy Affect the Donor Renal Function?

    W. Han, S. Yang, D. Joo, K. Huh, M. Kim, Y. Kim, S. Kim, K. Choi

    Urology, Yonsei University Health System, Urological Science Institute, Seoul, Republic of Korea; Surgery, The Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Republic of Korea

    Introduction and Objectives. In this study, we focused on histological abnormalities which found in living kidney donor implantation biopsy (IB) and analyzed with renal function…
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