ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Excellent Results of Living-Related Renal Transplant Recipients Treated with High-Dose Mizoribine – Two Years Result of a Japanese Multicenter Study

    N. Yoshimura, K. Uchida, K. Yuzawa, Y. Fukuda, K. Akioka, M. Fujisawa, S. Lto, T. Nakatani, T. Horimi, H. Ushigome, K. Nishimura

    Prefectural University of Medicine, Kyoto, Japan; Aichi Medical University, Nagakute, Aichi, Japan; Mito Medical Center, Mito, Ibagaki, Japan; Koseiren Hiroshima General Hospital, Hatsukaichi, Hiroshima, Japan; Omihachiman Community Medical Center, Omihachiman, Shiga, Japan; Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan; Gifu University School of Medicine, Gifu, Japan; Osaka City University Graduate School of Medicine, Osaka, Japan; Kochi Health Sciences Center, Kochi, Japan; Hyogo Prefectural Nishinomiya Hospital, Nishinomiya, Hyogo, Japan

    (Aims) Mizoribine (MZR) has been developed as an immunosuppressive agent, but has a less potent immunosuppressive effect up to 3 mg/kg/day. The widespread use of…
  • 2013 American Transplant Congress

    Behavior of ADAMTS13 and Von Willebrand Factor Levels in Patients after Living Donor Liver Transplantation

    N. Takahashi, H. Wada, M. Usui, Y. Iizawa, R. Sato, T. Hujii, A. Tanemura, N. Kuriyama, Y. Azumi, I. Osawa, M. Kishiwada, S. Mizuno, H. Sakurai, M. Tabata, S. Isaji

    Hepatobiliary Pancreatic and Transplant Surgery, Mie University Graduate School of Medicine, Tsu, Mie, Japan; Department of Molecular and Laboratory Medicine, Mie University Graduate School of Medicine, Tsu, Mie, Japan

    Introduction : Thrombotic microangiopathy (TMA) is one of the important complications occurring after liver transplantation (LT), and it is suggested that a Von Willebrand factor…
  • 2013 American Transplant Congress

    Combination of Anti-BTLA Antibody (6B2) and Anti-PD-1 Antibody (PIM-2) Induced Indefinite Survival of Fully MHC-Mismatched Murine Cardiac Allograft

    X. Jin, M. Uchiyama, L. Yu, H. Bashuda, H. Yagita, M. Niimi

    Surgery, Teikyo University, Tokyo, Japan; Surgery, Harbin Medical University, Harbin, China; Immunology, Juntendo University Hospital, Tokyo, Japan

    Background: Programmed death (PD)-1 has been implicated in peripheral tolerance, and the coinhibitory receptor B and T lymphocyte attenuator (BTLA) has been implicated in the…
  • 2013 American Transplant Congress

    Agonistic Anti-BTLA mAb (3C10) Induced Prolongation of Murine Cardiac Allograft and Generation of IL-10 Dependent Regulatory CD4+ T Cells, An

    M. Uchiyama, X. Jin, Q. Zhang, L. Yu, H. Bashuda, H. Matsuda, H. Yagita, M. Niimi

    Immunology, Juntendo University Hospital, Tokyo, Japan; Surgery, Harbin Medical University, Harbin, China; Surgery, Teikyo University, Tokyo, Japan

    Background: The co-inhibitory receptor B and T lymphocyte attenuator (BTLA) has been implicated in the regulation of autoimmunity and may potentially play an important role…
  • 2013 American Transplant Congress

    Effect of Donor Right Hepatectomy on Regeneration of the Liver and the Spleen

    D. Kim, G. Na, T. Hong, Y. Yoo

    Surgery, Seoul St Mary's Hospital, Catholic University of Korea, Seoul, Republic of Korea

    Purpose: Donor hepatectomy for living donor liver transplantation accompanies physiomorphological changes of the liver and the spleen. Therefore, the long-term consequences of these organs should…
  • 2013 American Transplant Congress

    Effect of Sirtuin 1 Gene Expression on Mouse Islet Graft Survival, The

    Y. Kim, Y. Wee, M. Choi, J. Chang, C. Yun, D. Han

    Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Republic of Korea; Division of Nephrology, Department of Internal Medicine, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Republic of Korea; Department of Bioengineering, College of Engineering, Hanyang University, Seoul, Republic of Korea

    Purpose: Islet transplantation is a promising therapy for Type 1 diabetes, however clinical application has not been as successful as organ transplantation due to early…
  • 2013 American Transplant Congress

    Efficacy and Safety of 3 vs. 6 Months of Low-Dose Valganciclovir for Prevention of Cytomegalovirus Disease in Moderate-Risk (D+/R+) Renal Transplant Recipients Receiving Antilymphocyte Antibody Induction Therapy

    S. Gabardi, R. Cross, K. DePiero, T. Dick, A. Maldonado, P. Maxwell, J. Nelson, J. Park, K. Ueda, R. Weng, E. Newkirk

    Multicenter CMV Pharmacists Collaborative Study Group, Boston

    The cytomegalovirus (CMV) donor-positive/recipient-positive (D+/R+) population represents the largest group of at-risk renal transplant recipients (RTR). Practice guidelines on the prevention of CMV recommend prophylaxis…
  • 2013 American Transplant Congress

    Distinct Roles of CD137 and CD137L Bidirectional Signals in Candida albicans Infection

    H. Cho, B. Kwon, J. Lee, V. Tran, J. Chun, S. Park

    Department of Surgery, Ulsan University Hospital, College of Medicine, University of Ulsan, Ulsan, Republic of Korea; School of Biological Sciences, University of Ulsan, Ulsan, Republic of Korea; Department of Internal Medicine, Ulsan University Hospital, College of Medicine, University of Ulsan, Ulsan, Republic of Korea; Biomedical Research Center, Ulsan University Hospital, College of Medicine, University of Ulsan, Ulsan, Republic of Korea

    Invasive fungal infections by Candida albicans frequently cause mortality in immunocompromised patients, yet the cellular processes leading to this mortality remain ill-defined. Here, using genetic…
  • 2013 American Transplant Congress

    Effect of Plasmapheresis on Angiotensin II Type I Receptor Antibody

    H. Eng, R. Montgomery, M. Leffell, A. Zachary

    Immunogenetics Laboratory, Medicine, Johns Hopkins Medical Institutions, Baltimore, MD; Surgery, Johns Hopkins Medical Institutions, Baltimore, MD

    The presence of angiotensin II type I receptor (AT1R) antibody has been associated with renal allograft rejection. We determined the presence of AT1R antibody in…
  • 2013 American Transplant Congress

    Low-Dose Cyclosporine (CsA) Plus Mycophenolate Mofetil (MMF) and Prednisolone (Pred) Triple Immunosuppressive Protocol in Renal Transplantation

    H. Xiang, W. Xue, P. Tian, X. Ding, X. Pan, H. Yan, J. Hou, X. Feng, X. Tian, C. Ding

    Department of Renal Transplant, Center of Nephropathy, The First Affiliated Hospital, Medical College, Xi'an Jiaotong University, Xi'an, China

    BACKGROUND: In order to decrease the rate of adverse effects of cyclosporin, a low-dose CsA plus MMF and Pred triple immunosuppressive protocol was started from…
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