2013 American Transplant Congress
Cytomegalovirus and Post-Transplant Cancer: Protection, Predisposition or No Effect?
NHS Blood and Transplant, Bristol, United Kingdom
The role of Cytomegalovirus (CMV) in development of post-transplant de novo cancer is not established. Previous studies have suggested that CMV exposure is associated with…2013 American Transplant Congress
Urinary Transcript Expression Profile in Kidney Transplant Recipients Is Predictive for Post-Transplant Graft Function
There is evidence that non-invasive immunological monitoring may be useful in the early period after renal transplantion, particularly with regard to predicting acute rejection. It…2013 American Transplant Congress
Invasive Fungal Infection in Liver Transplant Recipients – Focus on Underestimated Risk Factors Associated with In-Hospital Mortality
Departments of Surgery and Anaestesiology, University Hospital, Regensburg, Germany
Background: Invasive fungal infections (IFIs) in liver transplant recipients are associated with increased mortality. Although the risk factors for developing IFIs have been extensively investigated,…2013 American Transplant Congress
Factors Affecting the Humoral Response to HLA Antigens
Medicine, Johns Hopkins University School of Medicine, Baltimore, MD
Post-transplant antibody (Ab) to donor HLA is associated with reduced graft survival, but it is unknown if some HLA antigens are more likely to induce…2013 American Transplant Congress
Novel Candidate Markers Characterizing Cellular Senescence in Aged Zero Hour Kidney Biopsies Predict Post Transplant Outcome
Advanced donor age adversely affects allograft outcome following renal transplantation. Candidate genes involved in cell-cycle regulation and telomere shortening have been already described as markers…2013 American Transplant Congress
Toll Like Receptor Signaling Pathway Activated and Inflammation Amplified in Naked Caspase-3 siRNA Preserved Auto-Transplant Porcine Kidneys
Background. In our previous study, naked caspase-3 siRNA infused into the renal artery during cold preservation was effective, but did not protect the auto-transplant kidneys…2013 American Transplant Congress
Population Pharmacokinetics of Tofacitinib in De Novo Kidney Transplant Patients
Introduction: Tofacitinib is a novel, oral Janus kinase inhibitor being investigated as a targeted immunomodulator. Tofacitinib achieved comparable rate of biopsy-proven acute rejection and improved…2013 American Transplant Congress
Donor Derived Transmission Events in 2012: A Report of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC)
The OPTN DTAC, a multidisciplinary committee, evaluates potential donor derived transmission events (PDDTE), including infections (I) & malignancies (M), to assess for donor transmitted events.Methods:…2013 American Transplant Congress
Lung Recipients with Post-Transplant Lung Cancer and Comparison with Other Organ Recipients
The burden and impact of lung cancer among transplant recipients and a comparison between recipients of lung and other organs has been studied in small…2013 American Transplant Congress
Sepsis after Renal Transplantation: Clinical, Microbiological, and Immunological Characteristics
As immunosuppressive drugs and allograft survival have improved over the last decades, infection has become the main hurdle of patient survival and long-term allograft function…