2013 American Transplant Congress
Pediatric Steroid-Free Deceased-Donor Renal Transplantation with Alemtuzamab Induction: A Seven-Year Experience
INTRODUCTION AND OBJECTIVES: Alemtuzumab (Campath-1H, C1H) is a monoclonal antibody targeting CD52 receptors on B- and T-lymphocytes and is an effective induction agent in renal…2013 American Transplant Congress
Five Year Survival and Graft Function with the Clinical Use of Gene Expression Profiling for Rejection Surveillance
Purpose: Gene expression profiling (GEP) offers a non-invasive alternative to surveillance with endomyocardial biopsies. We sought to assess the medium-term survival and graft function in…2013 American Transplant Congress
Effects of Various Therapeutic Levels of Tacrolimus on Early Post Transplant Outcomes
University of Florida, Gainesville
Background: In striving to achieve early tacrolimus therapeutic levels, there is a risk of overshooting and achieving supratherapeutic or toxic levels. We studied our patients…2013 American Transplant Congress
Three-Gene Signature of Tolerance for Clinical Application in Kidney Transplant Recipients
Long-life immunosuppression is an important factor that contributes to shorten the long-term survival of kidney transplant recipients. Identifying patients in whom donor-specific tolerance has developed…2013 American Transplant Congress
Expanding the Deceased Donor Pool
Int Med, Univ of Calif Davis, Sacramento, CA; Surgery, Univ of Calif, Davis, Sacramento, CA
The rate of listing of candidates for kidney transplantation continues to exceed the rate of transplantation. To narrow this gap the conventional boundaries for deceased…2013 American Transplant Congress
Intended and Unintended Consequences of Share 35
University of Chicago, Chicago, IL
Purpose: To evaluate the impact of Share-35 implemented 9/30/05 by the United Network for Organ Sharing (UNOS) that gives pediatric patients with end stage renal…2013 American Transplant Congress
HLA Class II Mismatch Is Associated with Higher Incidence of Antibody Mediated Rejection after Heart Transplantation
UTAH Cardiac Transplant Program, Salt Lake City, UT
Background:Whether HLA-mismatch is associated with higher rates of antibody-mediated rejection (AMR) after heart transplantation (HTx), and whether Class I and Class II antigens have a…2013 American Transplant Congress
Low Affinity Memory CD8+ T Cells Are Potently Alloreactive Against High Affinity Antigen in a Model of T Cell Receptor Cross-Reactive Heterologous Immunity
Emory Transplant Center, Atlanta, GA
T cell activation in the context of both protective immunity and alloreactivity involves contact between the T cell receptor (TCR) and antigen presented as the…2013 American Transplant Congress
Opportunities for Expanding the Deceased Donor Pool in an Era of Outcomes-Driven Health Care
Background: The rate of listing of candidates for kidney transplantation continues to exceed the rate of transplantation. In an attempt to narrow this gap the…2013 American Transplant Congress
Pediatric Size Matched Single Renal Transplantation
Background: Pediatric cadaveric kidneys from small donors are offered as en bloc kidneys for transplantation. Recent data supports using these en bloc kidneys in pediatric…