ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Pediatric Steroid-Free Deceased-Donor Renal Transplantation with Alemtuzamab Induction: A Seven-Year Experience

    F. Darras, J. Melquist, H. DiCarlo, D. Connolly, W. Waltzer, R. Fine, K. Supe-Markovina

    Urology/Renal Transplantation, Stony Brook Medicine, Stony Brook, NY; Pediatrics, Stony Brook Medicine, Stony Brook, NY; Urology, Johns Hopkins, Baltimore, MD

    INTRODUCTION AND OBJECTIVES: Alemtuzumab (Campath-1H, C1H) is a monoclonal antibody targeting CD52 receptors on B- and T-lymphocytes and is an effective induction agent in renal…
  • 2013 American Transplant Congress

    Five Year Survival and Graft Function with the Clinical Use of Gene Expression Profiling for Rejection Surveillance

    J. Teuteberg, C. Yost, C. Newman, C. Grabowski, R. Kormos, D. McNamara, R. Zomak, C. Bermudez, M. Shullo

    Heart and Vascular Institute, University of Pittsburgh, Pittsburgh, PA; Pharmacy and Therapeutics, University of Pittsburgh, Pittsburgh, PA

    Purpose: Gene expression profiling (GEP) offers a non-invasive alternative to surveillance with endomyocardial biopsies. We sought to assess the medium-term survival and graft function in…
  • 2013 American Transplant Congress

    Effects of Various Therapeutic Levels of Tacrolimus on Early Post Transplant Outcomes

    S. Rehman, X. Wen, M. Casey, A. Santos, K. Andreoni

    University of Florida, Gainesville

    Background: In striving to achieve early tacrolimus therapeutic levels, there is a risk of overshooting and achieving supratherapeutic or toxic levels. We studied our patients…
  • 2013 American Transplant Congress

    Three-Gene Signature of Tolerance for Clinical Application in Kidney Transplant Recipients

    I. Rebollo-Mesa, P. Mobillo, E. Nova-Lamperti, S. Norris, Y. Kamra, M. Runglall, GAMBIT Consortium, Immune Tolerance Network, Indices of Tolerance Consortium, G. Lord, R. Lechler, M. Hernandez-Fuentes

    MRC Centre for Transplantation, King's College London, London, United Kingdom; NIHR BRC at GSTT, KCL and KCH, London, United Kingdom; www.GAMBITstudy.co.uk; www.immunetolerance.org; www.transplantation-tolerance.co.uk; King's Health Partners, London, United Kingdom

    Long-life immunosuppression is an important factor that contributes to shorten the long-term survival of kidney transplant recipients. Identifying patients in whom donor-specific tolerance has developed…
  • 2013 American Transplant Congress

    Expanding the Deceased Donor Pool

    D. Adey, R. Perez, M. Alnimri, A. de Mattos

    Int Med, Univ of Calif Davis, Sacramento, CA; Surgery, Univ of Calif, Davis, Sacramento, CA

    The rate of listing of candidates for kidney transplantation continues to exceed the rate of transplantation. To narrow this gap the conventional boundaries for deceased…
  • 2013 American Transplant Congress

    Intended and Unintended Consequences of Share 35

    C. Chesley, W. Parker, L. Ross, J. Thistlethwaite, Jr

    University of Chicago, Chicago, IL

    Purpose: To evaluate the impact of Share-35 implemented 9/30/05 by the United Network for Organ Sharing (UNOS) that gives pediatric patients with end stage renal…
  • 2013 American Transplant Congress

    HLA Class II Mismatch Is Associated with Higher Incidence of Antibody Mediated Rejection after Heart Transplantation

    A. Saidi, G. Snow, K. Brunisholz, E. Hammond, O. Wever-Pinzon, S. Drakos, C. Selzman, P. Revelo, R. Alharethi, D. Miller, J. Nativi-Nicolau, B. Reid, D. Budge, E. Gilbert, A. Kfoury, J. Stehlik

    UTAH Cardiac Transplant Program, Salt Lake City, UT

    Background:Whether HLA-mismatch is associated with higher rates of antibody-mediated rejection (AMR) after heart transplantation (HTx), and whether Class I and Class II antigens have a…
  • 2013 American Transplant Congress

    Low Affinity Memory CD8+ T Cells Are Potently Alloreactive Against High Affinity Antigen in a Model of T Cell Receptor Cross-Reactive Heterologous Immunity

    S. Krummey, C. Larsen, M. Ford

    Emory Transplant Center, Atlanta, GA

    T cell activation in the context of both protective immunity and alloreactivity involves contact between the T cell receptor (TCR) and antigen presented as the…
  • 2013 American Transplant Congress

    Opportunities for Expanding the Deceased Donor Pool in an Era of Outcomes-Driven Health Care

    D. Adey, R. Perez, M. Alnimri, A. De Mattos

    Internal Medicine, Univ of Calif, Davis, Sacramento, CA; Surgery, Univ of Calif, Davis, Sacramento, CA

    Background: The rate of listing of candidates for kidney transplantation continues to exceed the rate of transplantation. In an attempt to narrow this gap the…
  • 2013 American Transplant Congress

    Pediatric Size Matched Single Renal Transplantation

    M. McMellen, J. Hopping, S. Wilson, E. Wood, E. Abraham, M. Schnitzler, J. Tuttle-Newhall

    Department of Surgery, Division of Transplant Surgery, St Louis University, St Louis, MO; Department of Pediatrics, Division of Nephrology, SSM Cardinal Glennon Medical Center, St Louis, MO

    Background: Pediatric cadaveric kidneys from small donors are offered as en bloc kidneys for transplantation. Recent data supports using these en bloc kidneys in pediatric…
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