ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    BK Virus (BKV) Infection in Renal Transplantation: Excellent Outcomes with a Protocol of Intensive Post-Transplant Screening with Reduction in Immunosuppression & Treatment with Leflunomide and/or Low Dose Cidofovir

    C. Varma, G. Cipollina, M. Le, M. Gupta, A. Kotru

    Transplant & Liver Surgery, Geisinger Medical Center, Danville, PA

    Purpose: BKV infection is associated with a progressive decline in renal function in renal transplant recipients with a significant incidence of graft loss (30-40%) in…
  • 2013 American Transplant Congress

    Disparate Performance of Two Commonly Used Glomerular Filtration Rate Estimation Equations in Lung Transplant Patients

    B. Stephany, E. Poggio, E. Wehbe

    Nephrology & Hypertension, Cleveland Clinic, Cleveland, OH; The Kidney Institute, Nephrology, Dialysis & Transplantation, Houston, TX

    Purpose: The abbreviated Modification of Diet in Renal Disease (MDRD) and CKD-Epi equations employ the same variables (creatinine, race, gender) and are both commonly used…
  • 2013 American Transplant Congress

    Chemokine Responses as Surrogates of CMV Cell-Mediated Immunity and Predictors of Outcomes in Transplant Recipients

    L. Lisboa, A. Egli, D. O'Shea, S. Prabhakaran, V. Roth, S. Husain, D. Kumar, A. Humar

    University of Alberta, Edmonton, Canada; University of Basel, Basel, Switzerland; University of Toronto, Toronto, Canada

    Background: CMV-specific T-cell responses are crucial to protection of transplant patients against CMV viremia and disease. While studies have centered on CMV cytotoxic T-cells, using…
  • 2013 American Transplant Congress

    Role of Microcirculatory Integrity in DCD Ex-Vivo Organ Perfusion

    Q. Liu, A. Nassar, K. Farias, C. Tom, A. Bennett, G. D'Amico, K. Abu-Elmagd, J. Fung, C. Miller, C. Quintini

    Cleveland Clinic, Cleveland, OH; Case Western Reserve University, Cleveland, OH

    Introduction: Normothermic machine perfusion (NMP) represents a new preservation modality that could allow for better preservation of marginal donors such as donor after cardiac death…
  • 2013 American Transplant Congress

    Survival Benefit of a Third Kidney Transplant, The

    R. Redfield, A. Wood, P. Abt, M. Levine

    Department of Transplant Surgery, University of Pennsylvania, Philadelphia, PA

    Background: The size of the kidney wait list as well as the waiting time is increasing in the US. Given the current shortage of renal…
  • 2013 American Transplant Congress

    Ischemia-Induced ATF6 Upregulation Is a Key Factor in Liver Pro-Inflammatory Immune Response Against Ischemia Reperfusion

    J. Rao, S. Yue, J. Zhu, R. Bussutil, J. Kupiec-Weglinski, L. Lu, Y. Zhai

    Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA; Liver Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiansu Province, China

    Background and Aim: We have shown previously that endoplasmic reticulum (ER) stress may function in synergy with TLR4 in liver IRI to facilitate pro-inflammatory immune…
  • 2013 American Transplant Congress

    LineageProfiler: A Novel Informatics Tool for Unraveling Transplant Injury

    N. Salomonis, M. Naesens, T. Sigdel, M. Sarwal

    California Pacific Medical Center, San Francisco; University Hospitals Leuven, Leuven, Belgium

    Background: A significant challenge in the field of allograft transplantation is the efficient evaluation of tissue-specific immune responses and infiltrating immune cell types.Method: We have…
  • 2013 American Transplant Congress

    Kidney Dialysis after Heart Transplantation: The Short and Long Term Outcomes

    A. Osborne, J. Patel, M. Kittleson, M. Rafiei, D. Chang, L. Czer, J. Kobashigawa

    Cedars-Sinai Heart Institute, Los Angeles, CA

    BACKGROUND: In heart transplantation, acute renal failure is not uncommon immediately after heart transplantation. It may be due to pre-existing disease or due to the…
  • 2013 American Transplant Congress

    Comparative Effectiveness of Rabbit Anti-Thymocyte Globulin vs. Interleukin-2 Receptor Blockers in Deceased Donor Kidney Transplants with Delayed Graft Function, The

    A. Oweis, J. Zaltzman, J. Kim

    Department of Medicine, Division of Nephrology, University of Toronto, Toronto, ON, Canada

    Background: To date, studies addressing outcomes of depleting (i.e., rabbit anti-thymocyte globulin or rATG) vs. non-depleting (i.e., IL-2 receptor blocker or IL2RB) induction strategies in…
  • 2013 American Transplant Congress

    Increasing HLA DR Mismatches Is Associated with Inferior Kidney Allograft Outcome in Low Immune Risk Living Donor Kidney Transplant Recipients

    S. Lynch, K. Tinckam, J. Kim

    Department of Medicine, Division of Nephrology, Toronto General Hospital, University of Toronto, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, Toronto General Hospital, University of Toronto, Toronto, ON, Canada

    Background: HLA DR mismatches (MM) have been shown to negatively influence kidney allograft outcomes in historical cohorts. We examined whether this effect persists in the…
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