ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Utilization of Medicare Part D Among Transplant Recipients

    M. Chisholm-Burns, C. Spivey.

    University of Tennessee College of Pharmacy, Memphis, TN.

    Purpose: As cost is a critical barrier to medication access among transplant recipients, Medicare Part D represents a key strategy in medication acquisition. Due to…
  • 2015 American Transplant Congress

    Pre-Trasplant Perfusion With Mesenchymal Stromal Cells of Renal Graft Prevents Ischemia Injury Upregulating Gene Involved in Energy Saving

    V. Corradetti,1 S. Milanesi,1 E. Pattonieri,1 C. Rocca,1 T. Valsania,1 M. Gregorini,1 L. De Cecco,2 I. Benzoni,3 C. Bianco,3 M. Avanzini,4 M. Maestri,3 P. Esposito,1 T. Rampino,1 A. Dal Canton.

    1Unit of Nephrology, Dialysis and Transplantation, IRCCS Fondazione Policlinico San Matteo And University of Pavia, Pavia, Italy; 2Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milano, Italy; 3Unit of General Surgery, IRCCS Fondazione Policlinico San Matteo And University of Pavia, Pavia, Italy; 4Cell Factory Pediatric Oncohaematology, IRCCS Fondazione Policlinico San Matteo, Pavia, Italy.

    Background. Kidney ischemia from Donation after Circulatory Death shifts cells to anaerobic metabolism. Mesenchymal Stromal Cells (MSC) have immunomodulatory properties that are mediated by soluble…
  • 2015 American Transplant Congress

    Stem Cell and Novel Biologic Therapies to Enhance Functional Recovery in Limb Transplantation

    K. Kniery, M. DeHart, T. Brown, S. Salgar.

    Surgery/Clinical Investigation, Madigan Army Medical Center, Tacoma, WA.

    Introduction: Unlike visceral organ transplants, vascular composite allotransplantation such as limb and face require successful nerve regeneration and reinnervation of graft motor and sensory targets…
  • 2015 American Transplant Congress

    Beneficial Effects of Controlling Peritransplant Inflammation in Total Pancreatectomy With Islet Autotransplantation: A Single Center Experience With Large Cohort of Patients

    M. Takita,1 M. Kanak,2 R. Shahbazov,1 G. Yoshimatsu,1 M. Lawrence,1 A. Dabous,3 P. Kim,3 N. Onaca,3 B. Naziruddin,3 M. Levy.3

    1Islet Cell Laboratory, Baylor Research Institute, Dallas, TX; 2Institute for Biomedical Studies, Baylor University, Waco, TX; 3Baylor Annette C. and Harold C. Simmons Transplant Institute, Dallas, TX.

    Background: Total pancreatectomy with islet autotransplantation (TPIAT) is an effective surgical treatment for patients with intractable chronic pancreatitis (CP). We recently reported that significant mass…
  • 2015 American Transplant Congress

    Tolerant Kidney Transplant Patients Display B Cells With Regulatory Properties

    S. Brouard,1,2 M. Chesneau,1,3 L. Michel,1,2,3 E. Dugast,1,3 A. Chenouard,1,3 A. Pallier,1 D. Baron,1,3 J. Durand,1,3 F. Braza,1,3 P. Guerif,2 D.-A. Laplaud,1,2,3 J.-P. Soulillou,1,2,3 M. Giral,1,2,3 N. Degauque,1,3 E. Chiffoleau,1,3 S. Brouard.1,2

    1INSERM UMR 1064, Nantes, France; 2CHU de Nantes, ITUN, Nantes, France; 3Université de Nantes, Faculté de Médecine, Nantes, France.

    Whereas a B cell transcriptional profile has been recorded for operationally tolerant kidney graft patients, the role that B cells may play in this process…
  • 2015 American Transplant Congress

    Can Post-Transplant C-Peptide Be Used as an Indicator of Pancreas Graft Failure?

    R. Carrico,1 J. Fridell,2 J. Odorico,3 R. Stratta,4 K. Tyler,1 S. Niederhaus,5 R. Kandaswamy,6 J. Fisher,7 O. Olaitan,8 M. Mujtaba.2

    1UNOS, Richmond, VA; 2Indiana Univ School of Medicine, Indianapolis, IN; 3Univ Wisconsin Hospital and Clinics, Madison, WI; 4Wake Forest Baptist Medical Center, Winston-Salem, NC; 5Univ of Maryland Medical System, Baltimore, MD; 6Univ of MN Medical Center, Minneapolis, MN; 7Scripps Green Hospital, La Jolla, CA; 8Rush Univ Medical Center, Chicago, IL.

    Background: The OPTN Pancreas Transplantation Committee is attempting to define pancreas graft failure and performed a study to determine if C-peptide corresponds to pancreas graft…
  • 2015 American Transplant Congress

    Long-Term Metabolic Outcomes of Functioning Pancreas Transplants in Type 2 Diabetic Recipients

    S. Shin, Y. Kim, B. Choi, J. Choi, J. Jung, H. Cho, D. Han.

    Asan Medical Center, Seoul, Korea.

    Background Limited data are available on long-term metabolic outcomes of functioning pancreas transplants in patients with type 2 diabetes mellitus (T2DM). The aim of this…
  • 2015 American Transplant Congress

    Post-Donation Outcomes in 46 Live Pancreas Donors

    V. Kirchner, D. Sutherland, T. Dunn, E. Finger, T. Pruett, R. Kandaswamy.

    Division of Transplantation, Department of Surgery, University of Minnesota, Minneapolis, MN.

    Background: Live donor segmental pancreas transplants have been performed selectively to increase the pool of donors, minimize cold ischemia time, and to avoid brain death.…
  • 2015 American Transplant Congress

    The Impact of Duration of Brain Death on Outcomes in Abdominal Organ Transplantation: Rush and Retrieve or Rather Relax and Repair?

    C. Boffa,1 E. Curnow,2 K. Martin,2 R. Johnson,2 R. Ploeg.1

    1Nuffield Department of Surgical Sciences, Oxford, United Kingdom; 2NHS Blood and Transplant, Bristol, United Kingdom.

    Background: Brain death (BD) induces a progressive systemic pro-inflammatory and coagulatory response affecting function of the grafts-to-be and survival. With longer BD duration more injury…
  • 2015 American Transplant Congress

    HLA Broad Antigen and Eplet Mismatches in Determining the Risk of Acute Rejection After Kidney Transplantation

    H. Do Nguyen,1 W. Lim,1,2 J. Chapman,3 J. Craig,3,4 G. Wong.3,4

    1School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia; 2Renal Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia; 3Nephrology, The Children's Hospital at Westmead, Sydney, New South Wales, Australia; 4School of Medicine, University of New South Wales, Sydney, New South Wales, Australia.

    Aim: To determine the clinical relevance of HLA-ABDR broad antigen and eplet matching for predicting acute rejection after kidney transplantation.Background: HLAMatchmaker determines structurally HLA compatibility…
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