ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Eosinophilic Gastrointestinal Disease in Pediatric Liver and Kidney Transplant Recipients

    S. Mohammad,1 J. Bush,2 K. Amsden,1 A. Kagalwalla,1 H. Melin-Aldana,2 N. Arva.2

    1Pediatrics, Northwestern University, Chicago; 2Pathology, Northwestern University, Chicago.

    Eosinophilic gastrointestinal disease (EGID) has been associated with immunosuppression use in solid organ transplant recipients. However, its relationship to the post-transplant clinical course is unknown.…
  • 2015 American Transplant Congress

    Pediatric Liver Transplantation from Living Donors in Cali – Colombia

    L. Caicedo, V. Botero, J. Villegas, O. Serrano, M. Duque, M. Valderrama, E. Manzi, M. Agudelo, G. Echeverri.

    Transplant Unit, Fundacion Valle del Lili, Cali, Valle del Cauca, Colombia.

    Introduction. Starting a pediatric liver transplant program in a developing country, is a great challenge, due to technical difficulties and increased morbidity and mortality, and…
  • 2015 American Transplant Congress

    Risk Factors for Graft Loss in Pediatric Renal Transplant Recipients After Transfer of Care

    B. Coyne,1,2 P. Hollen,1,2 Y. Guofen,3 K. Brayman.4

    1Department of Pediatrics, University of Virginia Health System, Charlottesville, VA; 2School of Nursing, University of Virginia, Charlottesville, VA; 3Department of Public Health Sciences, University of Virginia Health System, Charlottesville, VA; 4Department of Surgery, University of Virginia Health System, Charlottesville, VA.

    Improvements in immunosuppression and transplant surgical technique have increased the survival of children with end-stage renal disease. These patients have complex needs, and the current…
  • 2015 American Transplant Congress

    Medication Adherence in Adolescents With Kidney Transplant and Chronic Kidney Disease: Patient/Caregiver Report Vs. Provider Perception

    C. Pruette,1 T. Brady,1 S. Mendley,2 B. Fivush,1 S. Tuchman,3 A. Green,1 M. Eakin,1 K. Riekert.1

    1Johns Hopkins University School of Medicine, Baltimore, MD; 2University of Maryland School of Medicine, Baltimore, MD; 3Children's National Medical Center, Washington, DC.

    Background: Medication adherence in adolescent kidney transplant (KT) recipients is poor, with non-adherence (NA) ranging from 5-71%, and NA is associated with poor graft survival.…
  • 2015 American Transplant Congress

    Risk Factors for Acute Cellular Rejection for Pediatric Kidney Transplant Recipients

    D. Cote,1 I. Bobanga,1 B. Vogt,2 K. Dell,2 R. Cunningham III,2 K. Noon,1 V. Humphreville,1 E. Sanchez,1 J. Schulak,1 K. Woodside.1

    1Department of Surgery, Case Western Reserve University & University Hospitals, Cleveland, OH; 2Department of Pediatrics, Case Western Reserve University & University Hospitals, Cleveland, OH.

    Background: Acute cellular rejection (ACR) potentially shortens the life of a kidney allograft. We sought to determine risk factors associated with the development of ACR…
  • 2015 American Transplant Congress

    New Insights in Clinical and Genetic Determinants of Longitudinal Dose-Corrected CNI Exposure in Children After Renal Transplantation

    N. Knops,1 M. van Dyck,1 E. Levtchenko,1 D. Kuypers,2 J. Herman.1

    1Pediatric Nephrology and Solid Organ Transplantation, University Hospitals Leuven, Leuven, Belgium; 2Nephrology and Renal Transplantation, University Hospitals Leuven, Leuven, Belgium.

    Purpose: Calcineurin-inhibitors (CNI) have a narrow therapeutic index and dosing is difficult due to inter- and intra-individual variation in pharmacokinetics (PK). Polymorphisms in genes involved…
  • 2015 American Transplant Congress

    Long-Term Follow-Up After Conversion from Twice-Daily Tacrolimus Formulation to Once-Daily Tacrolimus Formulation in Pediatric Kidney Transplantation

    C. Choi, A. Han, S. Min, S.-K. Min, T. Lee, I.-M. Jung, S. Kim, J. Ha.

    Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea.

    PurposeTacrolimus is one of the most frequently used immunosuppressants in pediatric kidney transplantation (KT) as in adult. In Pediatric kidney recipients, it is more important…
  • 2015 American Transplant Congress

    Home Dried Blood Spot Monitoring; a New Tool for Measuring Variability in Tacrolimus Blood Levels Over Time

    A. Al-Uzri, K. Freeman, K. Clark, L. Bleyle, S. Iragorri, R. Jenkins, D. Rozansky, D. Koop.

    Oregon Health & Science University, Portland, OR.

    PURPOSE: The measurement of variability in Tacrolimus (TAC) blood trough levels has been proposed to reflect the consistency with medication intake and adherence. A standard…
  • 2015 American Transplant Congress

    Preliminary Results of a Novel Induction Regimen Using Anti-Thymocyte Globulin (Rabbit) (rATG) Plus Basiliximab in a Pediatric Patient Population Undergoing Kidney Transplantation

    D. Halleran,1 S. Schurman, T. Welch, V. Whittaker.

    1Surgery, State University New York Upstate Medical University, Syracuse, NY; 2Pediatric Nephrology, State University New York Upstate Medical University, Syracuse, NY.

    Purpose: We report the outcomes from single center experience with the novel induction regimen using rATG (3 mg/kg) in divided doses given on operative day…
  • 2015 American Transplant Congress

    Pubertal Development in Pediatric Kidney Transplant Patients Receiving Everolimus Or Conventional Immunosuppression

    L. Pape,1 T. Ahlenstiel-Grunow,1 A. Zapf,2 M. Mynarek,3 J. Förster.1

    1Pediatric Nephrology, Hannover Medical School, Hannover, NDS, Germany; 2Medical Statistics, University Medical Center Göttingen, Göttingen, NDS, Germany; 3Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

    TOR inhibitors (mTORi) have been discussed to eventually influence pubertal development after pediatric kidney transplantation (Tx).This is the first trial to compare pubertal development in…
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