ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    The Immunosuppressive Effects of Erythropoietin Do Not Confer Lower Rates of Acute Rejection in Post Kidney Transplant Recipients Receiving Darbepoetin

    B. Fischbach,1 S. Gonzalez,1 A. Yango,1 A. Chandrakantan,2 A. Rajagopal,2 K. Rice,2 L. Melton,2 Y. Barri,2 M. Saim,2 N. Onaca,1 R. Ruiz,1 M. Levy,1 G. Klintmalm.2

    1Simmons Transplant Institute, Baylor All Saints Medical Center, Fort Worth, TX; 2Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX.

    Background: The correction of anemia has been associated with improved kidney allograft outcomes. Recently, erythropoietin was shown to directly suppress alloreactive human T-cells by inhibiting…
  • 2015 American Transplant Congress

    The Clinical Outcome of Plasma Cell-Rich Rejection of Kidney Allograft

    J. Hasegawa,1 K. Honda,2 S. Wakai,1 H. Shirakawa,3 M. Okumi,3 K. Omoto,3 H. Ishida,3 K. Tanabe.3

    1Nephrology, Ohkubo Hospital, Tokyo, Japan; 2Pathology, Tokyo Women's Medical University, Tokyo, Japan; 3Urology, Tokyo Women's Medical University, Tokyo, Japan.

    Background: Plasma cell-rich rejection (PCRR) is a rare type of allograft rejection characterized by the presence of mature plasma cells. This type of rejection has…
  • 2015 American Transplant Congress

    A Prospective Study of Renal Function and Histological Changes in Renal Transplant Recipients With Acute Clinical and Subclinical Rejection

    S. Chen,1 R. Mehta,1 P. Sood,1 P. Randhawa,2 N. Shah,1 C. Wu,1 A. Tevar,3 S. Hariharan.1

    1Nephrology, University of Pittsburgh Medical Center, Pittsburgh, PA; 2Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA; 3Transplant Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA.

    Background: To study the impact on renal function and histological changes in patients(pts) with acute clinical rejection(ACR) and subclinical rejection(SCR) from 3 to 12 month(m)…
  • 2015 American Transplant Congress

    Plasma Cell Infiltration: General Overview of Clinical and Pathological Correlations in Renal Transplantation

    C. Nihei, F. Lemos, D. David, P. Souza, F. de Paula, W. Nahas, E. David-Neto.

    Transplantation Service, Hospital das Clinicas-University of São Paulo, São Paulo, SP, Brazil.

    Background and Objective: Plasma cells are known as the final effectors of humoral immune response. Their significance and clinical outcomes are still controversial in kidney…
  • 2015 American Transplant Congress

    Reassessing Tubulitis and Interstitial Infiltrate: Creating a New Probabilistic Definition of TCMR

    P. Halloran, I. Salazar, M. Lopez, J. Chang.

    Alberta Transplant Applied Genomics Centre, Edmonton, Canada.

    Conventional diagnosis of T cell-mediated rejection (TCMR) in kidney transplant biopsies relies on interstitial inflammation (i-lesions), tubulitis (t-lesions), vasculitis (v-lesions) and experience-derived interpretation rules. The…
  • 2015 American Transplant Congress

    Alemtuzumab Induction Is Protective Against Acute Rejection in Kidney Recipients With Subtherapeutic Tacrolimus Concentrations

    K. Szempruch, R.-A. Lee, R. Dupuis, J. Deyo, T. Kozlowski.

    Transplant Surgery, University of North Carolina Hospitals, Chapel Hill, NC.

    Purpose: To determine the effect of attaining early therapeutic tacrolimus (TAC) trough concentrations on biopsy-proven acute rejection (BPAR) within 12 months post-transplantation in adult kidney…
  • 2015 American Transplant Congress

    Listing for Liver Transplantation of Patients With Hepatocellular Carcinoma Using the Extended Toronto Criteria; an Intention-to-Treat Analysis

    G. Sapisochin, N. Goldaracena, J. Laurence, A. Barbas, M. Dib, A. Ghanekar, M. Selzner, L. Lilly, I. McGilvray, M. Cattral, E. Renner, P. Greig, D. Grant.

    Multi-Organ Transplant, Toronto General Hospital. University of Toronto, Toronto, ON, Canada.

    The role of liver transplantation for patients whose HCC exceeds Milan criteria remains controversial. At the University of Toronto, we have reported survivals of a…
  • 2015 American Transplant Congress

    Risk of Post Liver Transplant (LT) Hepatocellular Carcinoma (HCC) Recurrence Is 2-Fold Higher in Women Compared to Men With AFP Levels at LT Between 101-500

    M. Sarkar,1 J. Dodge,2 F. Yao,1 J. Roberts,2 N. Terrault,1 N. Mehta.1

    1Medicine, University of California, San Francisco, San Francisco; 2Surgery, University of California, San Francisco, San Francisco.

    Gender differences in HCC incidence are known, with men at greater risk than women. Pre transplant AFP levels strongly predict post LT HCC recurrence, though…
  • 2015 American Transplant Congress

    Alpha-Fetoprotein as a Modifier of Anatomic Criteria for Transplantation of HCC Patients

    A. Daoud,1,3 M. Ghobrial,1 L. Teeter,2 E. Graviss,2 E. Asham,1 S. Burroughs,1 A. Saharia,1 C. Mobley,1 S. Mogawer,3 A. Sholkamy,3 M. Elshazly,4 M. Boktour,1 A. Gaber.1

    1Transplant Center, Methodist Hospital, Houston, TX; 2Pathology and Genomic Medicine, Methodist Hospital, Houston, TX; 3Internal Medicine Department, Cairo University Medical school, Cairo, Egypt; 4Surgery Department, Cairo University Medical school, Cairo, Egypt.

    Background:The current listing criteria (Milan, UCSF) for Orthotropic Liver Transplants (OLT) in hepatocellular carcinoma (HCC) patients emphasize the anatomic features of the tumor such as…
  • 2015 American Transplant Congress

    Advanced Imaging Modalities for Hepatocellular Carcinoma: Is MRI With Eovist Really Better?

    M. Chen, H. Reich, M. Uffenheimer, Y. Nasseri, A. Annamalai.

    Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA.

    Introduction: Hepatocellular cancer (HCC) is a common indication for transplantation. Eovist (gadolinium-EOB-DTPA), compared to conventional gadolinium-enhanced MRI (MRI-Gd) or triple-phase contrast-enhanced computed tomography (CT), is…
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