2015 American Transplant Congress
Intrapatient Variability of Tacrolimus Blood Concentrations Following Renal Transplant – Acute Rejection or No Connection?
Background: A high degree of intrapatient variability (IPV) of tacrolimus blood concentrations has been associated with poor long-term outcome (1). Periods of under-exposure with increased…2015 American Transplant Congress
Impact of Positive Crossmatch Due to Non-HLA Antibodies on Graft Outcomes in Renal Transplantation
Houston Methodist Hospital, Houston, TX.
It is widely recognized that a positive allogeneic crossmatch (+alloXM) due to pre-existing human leukocyte antigen (HLA) antibodies is associated with early rejection episodes. However,…2015 American Transplant Congress
Significance of an Isolated Elevated PRA in Renal Transplantation
Houston Methodist Hospital, Houston, TX.
Transplant centers have traditionally discerned a patient's immunologic risk based on peak panel reactive antibody (PRA) levels. However, in a given patient, pre-transplant PRA may…2015 American Transplant Congress
Evaluation of Serum sCD30 as a Predictor in Kidney Transplant Recipients
Objective To explore the significance of serum CD30 in predicting acute rejection and pneumonia in kidney transplant recipients. Methods A total of 106 kidney transplant…2015 American Transplant Congress
A Noninvasive Diagnostic Test of Renal Allograft Rejection Using Urinary-Cell mRNA: A Comparison of Droplet Digital and Real-Time PCR
Background: The diagnosis of acute rejection in kidney transplantation is still standardized by an invasive renal biopsy. Noninvasive tests and biomarkers that can replace the…2015 American Transplant Congress
Prognostic Relevance of Rejection Episodes Detected Within the First 3 Weeks After Kidney Transplantation
Background:The relevance of cellular rejection events detected in the early phase after kidney transplantation for graft survival and function remains to be elucidated. Especially the…2015 American Transplant Congress
Impact of Subclinical Rejection (SCR) and Acute Clinical (ACR) in Renal Transplant Recipients
University of Pittsburgh Medical Center, Pittsburgh, PA.
The importance of diagnosing subclinical rejection and its short and long term impact remains controversial.We prospectively evaluated 296 patients who had a kidney transplant at…2015 American Transplant Congress
Histological Analysis in ABO-Compatible and Incompatible Kidney Transplantation By Performing 3-Month and 1-Year Protocol Biopsies
Background. ABO incompatible kidney transplantation (ABO-I KTx) is nowadays a well-established procedure to expand living donor source. Graft and patient survivals of ABO-I KTx were…2015 American Transplant Congress
Tacrolimus for the Treatment of Refractory Biopsy-Proven Acute Cellular Rejection in Patients on Belatacept-Based, CNI- and Steroid-Free Immunosuppression Regimens
1Univ of Cincinnati, Cincinnati; 2The Christ Hospital, Cincinnati.
Background: Tacrolimus (TAC) is effective as rescue treatment (tx) in renal transplant patients (pts) on cyclosporine-based immunosuppression (IS) who have recurrent or resistant acute rejection…2015 American Transplant Congress
Vitamin D Supplementation and Acute Rejection Following Kidney Transplantation
1Barnes-Jewish Hospital, St. Louis, MO; 2Washington University in St. Louis, St. Louis, MO.
Purpose: Low serum levels of vitamin D have been associated with deleterious effects post-transplantation, including increased risk of rejection. Low serum vitamin D levels are…
American Transplant Congress abstracts