ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Recreational Marijuana Use Is Not Associated With Worse Kidney Allograft Outcomes

    G. Greenan, M. Anders, A. Leeser, J. Bromberg, S. Niederhaus.

    Department of Surgery, University of Maryland, Baltimore, MD; Department of Anesthesiology, University of Maryland, Baltimore, MD; Department of Surgery, University of Maryland, Baltimore, MD; Department of Surgery, University of Maryland, Baltimore, MD; Department of Surgery, University of Maryland, Baltimore, MD.

    Background: As marijuana (MJ) legalization is ongoing, kidney transplant programs need to develop listing criteria for MJ users. No data exist on whether recreational MJ…
  • 2015 American Transplant Congress

    Incidence and Clinical Severity of Hypogammaglobulinemia (Hypo-IgG) in Highly-HLA Sensitized Patients (HS) Undergoing Desensitization (DES)

    A. Vo,1 S. Ge,2 A. Petrosyan,2 M. Toyoda,2 J. Choi,1 J. Kahwaji,1 A. Peng,1 R. Villicana,1 S. Jordan.1

    1Kidney Transplant, Cedars-Sinai Medical Center, LA; 2Transplant Immunology Laboratory, Cedars-Sinai Medical Center, LA, CA.

    Introduction: Desensitization therapies (DES) have dramatically improved rates of transplantation among HS patients. However, antibody-reduction and B-cell/plasma cell directed therapies could have implications for humoral…
  • 2015 American Transplant Congress

    Infectious Complications With Plasmapheresis in Combination With Antithymocyte Globulin Compared to Antithymocyte Globulin Alone in the Treatment of Acute Rejection

    A. Leino, A. Hulbert, A. Delahunty, A. Rajab, J. Von Visger, H. Winters.

    The Comprehensive Transplant Center, The Ohio State University Wexner Medical Center, Columbus, OH.

    Background: Due to the complex nature of acute rejection (AR), multiple therapeutic modalities are necessary to prevent graft loss. The combination of prolonged cell depletion…
  • 2015 American Transplant Congress

    Does Infection Impact On Tacrolimus Blood Levels in Kidney Transplant Recipients?

    N. Kanaan,1 C. Percy,1 Z. Hassoun,2 M. Mourad,3 C. Beguin,4 M. De Meyer,3 E. Goffin.1

    1Nephrology, Cliniques Universitaires Saint Luc, Brussels, Belgium; 2Gastroenterology, Cliniques Universitaires Saint Luc, Brussels, Belgium; 3Abdominal Surgery and Transplantation, Cliniques Universitaires Saint Luc, Brussels, Belgium; 4Medical Information and Statistics, Cliniques Universitaires Saint Luc, Brussels, Belgium.

    Background Tacrolimus (Tac) is the cornerstone of immunosuppressive therapy in kidney transplant recipients. It is metabolized by members of the cytochrome p450 (CYP) 3A subfamily…
  • 2015 American Transplant Congress

    Implementation of Pre-Transplant Infectious Disease Risk Assessment: Sustained Success With Rapid-Cycle Improvement

    L. Danziger-Isakov, S. Blum, D. Dahale, B. Morrow, R. Rengering, D. Schoborg, S. Stark, E. Wells, A. Lorts, U. Kotagal, J. Bucuvalas.

    Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

    Pre-transplant infectious disease risk assessment can identify and mitigate potential risk for transplant candidates to improve post-transplant outcomes. We aimed to improve pre-transplant ID risk…
  • 2015 American Transplant Congress

    A Retrospective Study to Describe the Epidemiology and Outcomes of Opportunistic Infections After Solid Organ Transplantation

    M. Helfrich,1 P. Dorschner,1 M. Ison.1,2

    1Northwestern University Transplant Research Collaborative, Chicago; 2Infectious Diseases and Organ Transplantation, Northwestern University Feinberg SoM, Chicago.

    Background: Solid organ transplant (SOT) recipients are at increased risk for infections due to their complex medical conditions and use of immunosuppressive therapies. Despite significant…
  • 2015 American Transplant Congress

    Risk Factors for Infections After Transplant in a Prospective Cohort Study Including Incompatible Kidney Transplant Recipients

    R. Avery,1 H.-L. Tsai,2 C.-Y. Huang,2 S. Shoham,1 D. Ostrander,1 N. Lu,1 R. Montgomery,3 K. Marr.1

    1Infectious Disease, Johns Hopkins, Baltimore, MD; 2Biostatistics and Bioinformatics, Johns Hopkins, Baltimore, MD; 3Transplant Surgery, Johns Hopkins, Baltimore, MD.

    Background: Infectious morbidity is a cumulative function of recurrent events. Historically, data collection has depended on time-to-event analyses, variable definitions, and retrospective data. To better…
  • 2015 American Transplant Congress

    Return to Work and Occupational Infection Risks in Transplant Recipients

    R. Avery,1 D. Ostrander,1 S. Shoham,1 S. Alp,2 N. Lu,1 C. Cave,1 E. Kraus,3 K. Marr.1

    1Infectious Disease, Johns Hopkins, Baltimore, MD; 2Infectious Diseases and Clinical Microbiology, Hacettepe University Faculty of Medicine, Ankara, Turkey; 3Nephrology, Johns Hopkins, Baltimore, MD.

    Background: Counseling is commonly provided to transplant recipients who are planning to return to work, regarding potential infection risks in the workplace. However, the nature…
  • 2015 American Transplant Congress

    Outbreak of Pandemic Influenza A (H1N1pdm) in a Kidney Transplant Unit – The Protective Effect of Vaccination

    I. Helanterä,1 V.-J. Anttila,2 M. Lappalainen,3 M. Lempinen,1 H. Isoniemi.1

    1Department of Transplant and Liver Surgery, Helsinki University Central Hospital, Helsinki, Finland; 2Department of Infectious Diseases, Helsinki University Central Hospital, Helsinki, Finland; 3Department of Virology, Helsinki University Central Hospital, Helsinki, Finland.

    Background: Seasonal influenza vaccination is recommended for patients with end-stage renal disease, although the efficacy of the vaccination among these patients is unknown. We characterize…
  • 2015 American Transplant Congress

    Heterologous Immune Responses to Influenza Vaccine in Kidney Transplant Recipients

    D. Kumar,1 P. Campbell,2 K. Hoschler,3 A. Humar.1

    1Univ Health Network, Toronto, Canada; 2Univ of Alberta, Edmonton, Canada; 3Public Health England, London, United Kingdom.

    Background:Influenza vaccine is known to have suboptimal immunogenicity in transplant recipients. However, influenza vaccine may have the added benefit of inducing a cross-reactive immune response…
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