ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Spleen-Preserving Total Pancreatectomy with Islet Autotransplantation with Complete Preservation of the Splenic Arterial and Venous Supply Does Not Impact Islet Yield and Function

    M. Coluzzi, B. Naziruddin, G. Saracino, G. Testa, E. Beecherl, N. Onaca

    Baylor University Medical Center, Dallas, TX

    *Purpose: Typically, Total Pancreatectomy with Islet Autotransplantation (TPIAT) includes splenectomy. Spleen sparing TPIAT was described in the literature using the Warshaw technique, with proximal ligation…
  • 2022 American Transplant Congress

    Prebiotic Supplementation In Kidney Transplant Recipients For Preventing Infections And Gastrointestinal Upset: A Randomized Controlled Feasibility Study

    S. Chan1, C. M. Hawley1, E. M. Pascoe2, C. Z. Cao2, S. B. Campbell2, K. L. Campbell3, R. S. Francis2, R. Hale1, N. M. Isbel4, M. Morrison5, D. W. Johnson2

    1Department of Nephrology, Princess Alexandra Hospital, Woolloongabba, Australia, 2Princess Alexandra Hospital, Woolloongabba, Australia, 3Menzies Health Institute - Molecular Basis of Disease Research Program, Griffith University, Brisbane, Australia, 4Princess Alexandra Hospital, Brisbane, Australia, 5Diamantina Institute, Faculty of Medicine, The University of Queensland, Woolloongabba, Australia

    *Purpose: Modulating the large intestinal microbiome of kidney transplant recipients (KTR) may reduce infectious complications. The aim of this study was to assess the feasibility…
  • 2022 American Transplant Congress

    Bacterial Infections After Kidney Transplant Before and After the COVID-19 Pandemic

    A. Perez Gutierrez1, B. Juengel1, S. Krishnamoorthy2, P. J. Bachul1, P. Witkowski3, R. Barth3, J. Fung1

    1Department of Surgery, University of Chicago Medicine, Chicago, IL, 2Department of Medicine, University of Chicago Medicine, Chicago, IL, 3University of Chicago Medicine, Chicago, IL

    *Purpose: Infectious complications are a major cause of mortality and morbidity after kidney transplantation. During the COVID-19 pandemia there were several changes in the management…
  • 2022 American Transplant Congress

    Utility of Protocol Pancreas Biopsies for De Novo Donor-Specific Antibodies

    S. Parajuli, D. Mandelbrot, J. Odorico

    University of Wisconsin, Madison, WI

    *Purpose: Donor-specific antibodies (DSA) against the human leukocyte antigens (HLA) can now be measured accurately and repetitively, and are routinely monitored post-transplant. In recipients of…
  • 2022 American Transplant Congress

    Incidence and Risk Factors Associated with the Development of Hypoglycemia After Combined Pancreas-Kidney Transplantation

    S. Kapoor1, S. Jain2, S. Stefan3, Y. Azzi3, M. Ajaimy3, P. Loarte-Campos3, C. Pynadath3, H. C. Yaffe3, M. Le3, J. Rocca3, S. Greenstein3, M. Kinkhabwala3, J. Graham3, E. Akalin4, L. Liriano-Ward3

    1Montefiore Medical Center, New York, NY, 2Montefiore Medical Center, Scarsdale, NY, 3Montefiore Medical Center, Bronx, NY, 4Albert Einstein College of Medicine, Montefiore Medical Ctr, Bronx, NY

    *Purpose: To review the incidence of hypoglycemia after pancreas transplantation in recipients with type 1 and 2 diabetes mellitus and the risk factors associated with…
  • 2022 American Transplant Congress

    Biological Functions of Circulating miRNAs in Patients with Chronic Pancreatitis Undergoing Total Pancreatectomy with Islet Autotransplantation

    S. Vasu1, C. Darden2, Y. Liu3, M. Lawrence4, B. Naziruddin1

    1Baylor University Medical Ctr, Dallas, TX, 2Baylor University, Waco, TX, 3-Baylor University Medical Center, Dallas, TX, 4Baylor University Medical Center, Dallas, TX

    *Purpose: Our previous reports showed that in patients with Chronic Pancreatitis (CP), specific microRNAs (miRNA) were elevated in circulation before, during islet infusion and after…
  • 2022 American Transplant Congress

    Kidney Transplantation from Deceased Donors with Vaccine-Induced Thrombosis and Thrombocytopenia: An Updated Analysis of the UK Experience

    G. Greenhall, ,. UK VITT Donor Kidney Transplant Study Group

    NHS Blood and Transplant, Bristol, United Kingdom

    *Purpose: Vaccine-induced thrombosis and thrombocytopenia (VITT) is a rare syndrome that has emerged since widespread vaccination against SARS-CoV-2. As a result of the high mortality,…
  • 2022 American Transplant Congress

    The Use of Donor-Derived Cell-Free DNA in Female and Male Heart Transplant Recipients: A Sex-Specific Analysis of the Surveillance Heartcare Outcomes Registry

    E. M. DeFilippis1, Y. Fu2, R. Burke2, M. Deng3, M. Kamath4, L. Lourenco Jenkins2, A. R. Vest5

    1Columbia University Irving Medical Center, New York, NY, 2CareDx, Brisbane, CA, 3David Geffen School of Medicine at UCLA, Los Angeles, CA, 4Ronald Reagan UCLA Medical Center, Los Angeles, CA, 5Tufts Medical Center, Boston, MA

    *Purpose: To investigate sex-specific donor-derived cell-free DNA AlloSure (AS) levels during allograft quiescence and rejection after heart transplantation.*Methods: Sex-stratified data were obtained from the Surveillance…
  • 2022 American Transplant Congress

    Islet-Derived Exosomes Carry Self-Antigens and May Induce Autoimmunity After Transplantation

    S. Vasu1, C. Darden2, J. Mattke2, Y. Liu3, M. C. Lawrence3, B. Naziruddin1

    1Baylor University Medical Ctr, Dallas, TX, 2Baylor University, Waco, TX, 3Baylor University Medical Center, Dallas, TX

    *Purpose: Our earlier observations revealed release of exosomes from human islets containing microRNAs (miRNA) specific to islet stress and damage in vitro and in vivo…
  • 2022 American Transplant Congress

    Early Kidney Transplantation Irrespective of Donor Profile Offers Survival Benefit in Recipients Older Than 70 Years

    A. Mujkanovic1, T. Jarmi2, C. B. Taner1, K. P. Croome1, S. A. Mao1

    1Transplant Surgery, Mayo Clinic, Jacksonville, FL, 2Transplant Medicine, Mayo Clinic, Jacksonville, FL

    *Purpose: Donor and recipient pre-transplant risk factors are known to influence post-transplant recipient survival. This study’s purpose was to identify the most important donor and…
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