2015 American Transplant Congress
Kidney Patients at High Immunological Risk Can Be Safely Transplanted With a Novel Induction Regimen Using Anti-Thymocyte Globulin (Rabbit) (rATG) Plus Basiliximab
Purpose: We report the outcomes from our single center experience with the novel induction regimen using rATG (3 mg/kg) in divided doses given on operative…2015 American Transplant Congress
Thymoglobulin Dosing Efficacy: The Role of ALC on Infection and Rejection
University of Minnesota, Minneapolis, MN.
There are varied Thymoglobulin® (Thymo) induction regimens accepted among transplant programs. Our center uses five doses of Thymo at 1.25mg/kg, yielding a total goal of…2015 American Transplant Congress
Alemtuzumab Dose Adjusted for Weight Reduces Infection Post-Renal Transplantation
Imperial College Kidney and Transplant Centre, Hammersmith Hospital, London, United Kingdom.
Alemtuzumab [AL] has been increasingly used as an induction agent in renal transplantation. It causes potent lymphocyte depletion and as has been shown to reduce…2015 American Transplant Congress
Immune-Mediated Injury in Kidney Transplant Recipients Treated With Alemtuzumab Induction and a Steroid Avoidance Protocol
McGill University Health Centre, Montreal, Canada.
Study purpose: We evaluated short-term clinical and immunological outcomes of kidney transplant recipients who received alemtuzumab induction and a steroid-avoidance protocol.Methods: This is a retrospective…2015 American Transplant Congress
Three Year Outcomes of Renal Allograft Transplants in African American Recipients Receiving Alemtuzumab for Induction Immunosuppression
Ochsner Clinic Foundation, New Orleans, LA.
Background:Induction with Alemtuzumab is well documented to reduce the incidence and severity of acute rejection episodes, which may improve graft survival. Limited data are available…2015 American Transplant Congress
Ideal Versus Total Body Weight Dosing of Rabbit Anti-Thymocyte Globulin Induction Therapy on Patient Outcomes in High Immunological Risk Kidney Transplant
Duke University Hospital, Durham, NC.
BackgroundThe optimal dose of rabbit anti-thymocyte globulin (rATG) induction therapy in high immunological risk kidney transplantation (KTx) lacks consensus and the effect of dosing weight…2015 American Transplant Congress
Efficacy and Safety of Induction Therapy With Monoclonal Versus Polyclonal Antibodies in Kidney Transplant Recipients in the Last Five Years (2008-2013) in Our Institution
Nephrology, La Paz Hospital, Madrid, Spain.
Induction immunosuppression in renal transplantation is not clearly defined. We analyze the efficacy and safety of the used regimens at our institution in the last…2015 American Transplant Congress
Induction With an Interleukin-2 Receptor Antagonist in Sensitized Adult Kidney Transplant Recipients Is Highly Effective and Safe
Background: The effectiveness and safety of induction with basiliximab (IL2RA) in sensitized kidney transplant recipients is not clearly established. The aim of this study was…2015 American Transplant Congress
Molecular Features of Kidney Transplant Biopsies Without Allograft Injury in Relation With Type of Induction Therapy
Objective: Molecular evidence of allograft injury might precede histopathological findings of allograft injury. We aimed to investigate if the type of induction therapy effect intragraft…2015 American Transplant Congress
IL-17 Production Influenced by Induction Therapy With ATG
Introduction Immune-mediated rejection remains the most important cause of graft failure. Recently, a newly identified CD4+ T cell subset, Th17, distinct from Th1 or Th2,…
American Transplant Congress abstracts