ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Clinicopathological Scenarios (CPS) Defined by Viremia, Creatinine and Histology in Polyomavirus Nephropathy Differ in 1st and 2nd (Follow-Up) Biopsy

    C. Drachenberg, M. Chaudhry, F. Yang, R. Ugarte, A. Haririan, M. Mavanur, C. Cangro, B. Thomas, N. Costa, E. Ramos, M. Weir, J. Papadimitriou.

    Pathology and Medicine, University of Maryland School of Medicine, Baltimore, MD.

    Studies of sequential kidney biopsies (KB) after the diagnosis of polyomavirus allograft nephropathy (PVN) are scarce and clinicopathological evolution of PVN poorly understood. In practice…
  • 2015 American Transplant Congress

    Plasmapheresis – A Previously Unrecognised Risk Factor for BK Viraemia

    E. Olayos,1 K. Barraclough,2 R. Walker,3 R. Masterson,2 H. Peter,2 C. Solomon.4

    1St Vincents Hospital, Fitroy, Victoria, Australia; 2Nephrology, Royal Melbourne Hospital, Parkville, Victoria, Australia; 3Nephrology, The Alfred Hospital, Prahran, Victoria, Australia; 4Nephrology, Western Hospital, Footscray, Victoria, Australia.

    BK nephropathy is an important preventable cause of graft loss, with the only universally accepted risk factor being overall burden of immunosuppression. In the absence…
  • 2015 American Transplant Congress

    Impact of Sirolimus on the Risk of BK Viremia in Simultaneous Pancreas-Kidney Transplant Recipients

    D. Wojciechowski, T. Yokoyama, S. Chandran, P. Stock.

    UCSF, San Francisco.

    BackgroundBK virus (BKV) is a common infection in simultaneous pancreas-kidney (SPK) transplant recipients. Data in kidney transplant recipients suggest that immunosuppression regimens containing an mTORi…
  • 2015 American Transplant Congress

    A Single Center Comparison of Various BK Viremia Elimination Protocols

    Y. Qazi, K. Lee, B. Duong, R. Dhawan, L. Shinn, L. Aguirre, C. Parke, C. Wong, S. Alexopoulos, D. Olson, M. Smogorzewski.

    Division of Transplantation, University Of Southern California. Keck Med Center, Los Angeles, CA.

    Aim BK infection remains a significant complication post kidney transplantation. Best practices in BK management have evolved over time. The purpose of the study was…
  • 2015 American Transplant Congress

    Evaluation of the Use of Leflunomide for the Prevention of BK Nephropathy in Renal Transplant Recipients- A Single Center Experience

    S. Jonchhe, E. Hollinger, S. Jensik, O. Olaitan, A. Hodowanec, M. Hertl, S. Fayek, E. Chan, C. Pullum, N. Alvey.

    Rush University Medical Center, Chicago, IL.

    Objective: The purpose of this study was to compare the efficacy of leflunomide in combination with reduced immunosuppression versus reduction of immunosuppression alone for the…
  • 2015 American Transplant Congress

    Evaluation of Leflunomide for the Treatment of BK Viremia and Biopsy Proven BK Nephropathy: A Single Center Experience

    N. Nesselhauf,1 J. Strutt,2 B. Bastani.1

    1Saint Louis University Hospital, St. Louis, MO; 2Minneapolis VA Health Care System, Minneapolis, MN.

    Purpose:The objective was to evaluate the use of leflunomide in BK viremia (BKV) and biopsy proven BK nephropathy (BKN) in kidney and kidney-pancreas transplant recipients.Methods:We…
  • 2015 American Transplant Congress

    Switching from Tacrolimus to Low-Dose Cyclosporine A Preserves Allograft Function in Presumptive and Definitive Polyomavirus-Associated Nephropathy

    G. Huang, C.-X. Wang, J.-G. Fei, J. Qiu, S.-X. Deng, J. Li, G.-D. Chen, Q. Fu, R.-H. Deng, L.-Z. Chen.

    Department of Organ Transplantation, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.

    Switching from tacrolimus(Tac) to low-dose cyclosporine A(CsA) is recommended for preventing BK virus-associated nephropathy(BKVAN) and preserving allograft function in BKVAN patients, but systematic evaluations were…
  • 2015 American Transplant Congress

    Validation of Predictive Nomograms for Delayed Graft Function in Kidney Transplant Recipients

    L. Chau, O. Famure, J. Kim.

    Multi-Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada.

    Background: Delayed graft function (DGF), defined by the need for dialysis within 7 days after transplantation, impacts short and long term graft outcomes. Predictive nomograms…
  • 2015 American Transplant Congress

    Prediction of Delayed Graft Function By Means of a Web-Based Calculator in Living Related Kidney Transplant: Mexican Single Center Experience

    G. Martinez-Mier,1 E. Soto-Miranda,1 M. Mendez Lopez,1 L. Budar Fernandez,1 M. Trujillo-Martinez,2 A. Uscanga-Montesano,2 D. Avila y Falfan.2

    1Organ Transplantation, IMSS UMAE189/HRAEV Nefrologia y Trasplantes de Veracruz, Veracruz, Mexico; 2Research, IMSS UMAE 189, Veracruz, Mexico.

    Background: Delayed graft function (DGF) is associated with, poor graft survival. Irish validated a model to predict DGF for deceased donor transplants. The model was…
  • 2015 American Transplant Congress

    Delayed Graft Function (DGF) in Kidney Transplant Recipients (KTRs) Is Associated With Early Allograft Inflammation and Progressive Fibrosis Within 3 Months

    A. Cherukuri, R. Mehta, P. Sood, S. Chen, G. Mour, A. Tevar, P. Randhava, S. Hariharan.

    University of Pittsburgh, Pittsburgh.

    DGF had been shown to be deleterious to KTR outcomes. Analysis of histological progression in KTRs with DGF was previously not attempted. In this prospective…
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