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American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Antibody Response Following Influenza Vaccination in Renal Transplant Recipients

    M. Mujtaba, B. Book, A. Sharfuddin, A. Khalil, S. Vaishnav, E. Wiebke, M. Yaqub, D. Mishler, T. Taber.

    Indiana University School of Medicne-IU Health, Indianapolis, IN.

    Purpose: Following the recommended consensus guidelines of ATC for vaccination, at our institution we recommend annual vaccination for influenza + H1N1 (Flu) for renal transplant…
  • 2015 American Transplant Congress

    Associations of Pre-Transplant Prescription Narcotic Use With Clinical Complications After Kidney Transplantation

    N. Lam,1 M. Schnitzler,2 J. Tuttle-Newhall,2 H. Xiao,2 D. Axelrod,3 D. Brennan,4 V. Dharnidharka,4 M. Nazzal,2 K. Lentine.2

    1Western University, London, ON, Canada; 2Saint Louis University, St. Louis, MO; 3Dartmouth Hitchcock Medical Center, Hanover, NH; 4Washington University School of Medicine, St. Louis, MO.

    Background: Associations of narcotic use before kidney transplantation with post-transplant clinical outcomes are not well described.Methods: We performed a retrospective analysis of linked national registry…
  • 2015 American Transplant Congress

    Patients With Severe and Morbid Obesity Benefit from Deceased Donor Kidney Transplant

    A. Nishio Lucar,1 J. Ma,2 G. Vranic,1 D. Keith.1

    1Medicine, University of Virginia, Charlottesville, VA; 2Biostatistics, University of Virginia, Charlottesville, VA.

    More than one in three Americans are obese yet obesity is considered a relative and sometimes absolute contraindication to kidney transplant. Previous studies suggest that…
  • 2015 American Transplant Congress

    Interim Safety Experience in Transplant Patients Treated With Belatacept (Nulojix) in the Post-Approval Setting

    T. Kou, J. Braga, S. Sibabrata, J. Preston, M. Harler, A. Gomez.

    Bristol-Myers Squibb Company, Princeton, NJ.

    Purpose: Belatacept is a selective T-cell costimulation blocker indicated for prophylaxis of organ rejection in adult patients receiving a kidney transplant in combination with basiliximab…
  • 2015 American Transplant Congress

    Adverse Events of Maintenance Immunosuppression Following Kidney Transplantation Reported in Randomized Controlled Trials: A Systematic Review

    M. Howell,1,2 R. Yeo,2 A. Tong,1,2 J. Craig,1,2 K. Howard,2 G. Wong.2,3

    1Centre for Kidney Research, The Children's Hospital at Westmead, Westmeand, NSW, Australia; 2School of Public Health, University of Sydney, Sydney, NSW, Australia; 3Centre for Transplant and Renal Research, Westmead Hospital, Westmead, NSW, Australia.

    Aim: To evaluate the completeness of reporting of adverse events in randomized controlled trials (RCTs) of maintenance immunosuppression in kidney transplantation.Background: Side effects of maintenance…
  • 2015 American Transplant Congress

    Emotional Bonding in Recipients of Deceased Donor Kidney Transplants (DDRT): Associated Factors and Effect on Medication Adherence

    A. Cerrato, M. Salifu, M. Markell.

    Division of Nephrology, SUNY Downstate Medical Center, Brooklyn, NY.

    The feelings of the kidney recipient towards his or her donor are complex and may affect behavior in the post-transplant period. We studied 152 DDRT…
  • 2015 American Transplant Congress

    The Occurrence of v- Lesions Is Not Associated With Decreased Graft Survival

    P. Halloran, I. Salazar, M. Lopez, J. Chang.

    ATAGC, Edmonton, Canada.

    Intimal arteritis (v-lesions) in kidney transplant biopsies has been believed to have major prognostic and diagnostic significance. We assessed the relationship of v-lesions to prognosis…
  • 2015 American Transplant Congress

    Kynurenine Assay to Detect Inflammation in Transplant Patient: Clinical Results

    D. Abendroth,1 J. Kaden,2 M. Marzinzig,1 M. Stangl.3

    1Center of Surgery, University of Ulm, Ulm, Germany; 2Renal Transplant Center, Municipal Friedrichshain Hospital, Berlin, Germany; 3General, Visceral and Transplant Surgery, Ludwig-Maximilians-Universität, München, Munich, Germany.

    Introduction: Ideal biomarker should be specific, sensitive, non-invasive, mirror the benefit of therapy and offer prognostic potential. We developed a test using a colorimetric assay…
  • 2015 American Transplant Congress

    T-Cell Mediated Vascular Rejection Can Be Identified By the Combined Measurement of Five Specific microRNAs in Blood

    M. Matz,1 K. Fabritius,1 C. Lorkowski,1 M. Dürr,1 J. Gaedeke,1 P. Durek,2 J. Grün,2 A. Goestemeyer,1 F. Bachmann,1 K. Wu,1 B. Rudolph,1 U. Weber,1 C. Haftmann,2 N. Unterwalder,3 N. Lachmann,1 A. Radbruch,2 H.-H. Neumayer,1 M.-F. Mashreghi,2 K. Budde.1

    1University Medicine Charité, Berlin, Germany; 2German Rheumatism Research Centre, Berlin, Germany; 3Labor Berlin GmbH, Berlin, Germany.

    MicroRNAs hold important roles in the regulation of gene expression. Their function has been correlated with kidney disease and they might represent a new class…
  • 2015 American Transplant Congress

    Th-17 Alloimune Responses in Renal Allograft Biopsies from Recipients of Kidney Transplants Using Extended Criteria Donors During Acute T-Cell Mediated Rejection

    M. Matignon,1,2 A. Aissat,3 F. Canoui-Poitrine,4 C. Grondin,2 D. Desvaux,5 D. Saadoun,6 P. Lang,1,2 J. Cohen,2 P. Grimbert.1,2

    1Nephrology Transplantation, APHP, Créteil, France; 2U955 Team 21, INSERM, Créteil, France; 3U955 Team 11, INSERM, Créteil, France; 4Public Health, APHP, Créteil, France; 5Anatomopathology, APHP, Créteil, France; 6Internal Medicine, APHP Pitié Salpêtrière, Paris, France.

    Although renal transplantation using expanded criteria donors has become a common practice, immune responses related to immunosenescence in those kidney allografts have not been studied…
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