ATC Abstracts

American Transplant Congress abstracts

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  • 2015 American Transplant Congress

    Development of a Targeted Genetic Renal Disease Panel With NexGen Sequencing for Unbiased Testing of Living Kidney Donors for Genetic Kidney Disease

    C. Thomas,1 Z. Stewart,3 A. Mansilla,2 S. Mason,2 A. Kwitek,2 C. Campbell,2 R. Smith,1,2 R. Smith.1,2

    1Internal Medicine, University of Iowa, Iowa City, IA; 2Institute of Human Genetics, University of Iowa, Iowa City, IA; 3Surgery, University of Iowa, Iowa City, IA.

    Recent studies indicate that living donors biologically related to their transplant recipient may be at higher risk of ESRD compared to unrelated donors, possibly secondary…
  • 2015 American Transplant Congress

    Risk of Cause-Specific ESRD in Live Kidney Donors

    S. Anjum, A. Muzaale, A. Massie, S. Bae, D. Segev.

    Johns Hopkins, Baltimore.

    The purpose of this study is to investigate the risk of developing cause-specific ESRD in live kidney donors over time.METHODS: We studied a cohort of…
  • 2015 American Transplant Congress

    Impact of Abdominal Aortic Calcification in Living Kidney Donors

    Y. Yoon,1 K. Choi,2 D. Joo,3 K. Huh,3 M. Kim,3 S. Kim,3 Y. Kim,3 S. Yang,2 W. Han.1

    1Department of Urology, Yonsei University College of Medicine, Seoul, Korea; 2Department of Urology, CHA University, Seongnam-si, Korea; 3Department of Transplantation Surgery, Yonsei University College of Medicine, Seoul, Korea.

    Introduction: To assess the association between abdominal aortic calcification (AAC) and renal function of living kidney donor and to evaluate the value of an AAC…
  • 2015 American Transplant Congress

    Implications of Living Donor Kidney Histology, Volume and Function on Post-Donation GFR

    Z. Zaky,1 B. Lankowsky,2 S. Shah,1 L. Herlitz,1 A. Chiesa-Vottero,1 K. Wallenfelsz,1 A. Caplin,1 D. Goldfarb,1 S. Flechner,1 J. Schold,1 E. Poggio.1

    1Glickman Urological & Kidney Institute, Cleveland Clinic, Cleveland, OH; 2CWRU School of Medicine, Cleveland, OH.

    Living kidney donor transplantation is the best modality for treating ESRD as it confers excellent outcomes to patients and it is safe for donors. Postdonation…
  • 2015 American Transplant Congress

    Impact of Cold Ischemic Time (CIT) and Distance Traveled (DT) on Shipped Kidneys in the OPTN/UNOS Kidney Paired Donation (KPD) Pilot Program (PP)

    M. Aeder,1 D. Stewart,2 R. Leishman,2 L. Robbins Callahan,2 A. Kucheryavaya,2 T. Sandholm,3 R. Formica.4

    1Univ Hosp Case Med Ctr, Cleveland, OH; 2UNOS, Richmond, VA; 3Carnegie Mellon Univ, Pittsburgh, PA; 4Yale Univ, New Haven, CT.

    Background: The success of a national KPD program is predicated on excellent early kidney function and graft survival (GS). As other KPD programs have reported…
  • 2015 American Transplant Congress

    Recovery After Living Donor Laparoscopic Nephrectomy

    D. Larson, J. Wiseman, D. Berglund, C. Jacobs, C. Garvey, H. Ibrahim, A. Matas.

    U of MN, Mpls.

    Living donors (LDs) require time away from daily activities and work for the surgery and recovery. In general, LDs are counselled that they should be…
  • 2015 American Transplant Congress

    Hybrid-Natural Orifice Transluminal Endoscopic Surgery (NOTES) for Laparoscopic Donor Nephrectomy Offers Better Postoperative Pain, Cosmesis and Surgical Outcomes Than Transumbilical Single Site Surgery

    M. Miura, H. Higashiyama.

    Department of Renal Transplantation Surgery, Sapporo Hokuyu Hospital, Sapporo, Japan.

    Objectives: Laparoendoscopic single site donor nephrectomy (LESSDN) via the umbilicus has been our standard care for living donors. Although we have previously reported better cosmetic…
  • 2015 American Transplant Congress

    Focal Segmental Glomerulosclerosis Recurrence in Renal Transplant Recipients Treated With Belatacept

    W. Kitchens,1 A. Farris,2 S. Pastan,1 T. Pearson,1 C. Larsen,1 A. Adams.1

    1Emory Transplant Center, Atlanta, GA; 2Department of Pathology, Emory University Hospital, Atlanta, GA.

    Introduction: Focal segmental glomerulosclerosis (FSGS) is a cause of end-stage renal failure that frequently recurs following renal transplant, often leading to early allograft loss. A…
  • 2015 American Transplant Congress

    Evaluation of Donor-Specific Antibodies Through 7 Years With Belatacept in BENEFIT and BENEFIT-EXT

    R. Bray,1 H. Gebel,1 R. Townsend,2 U. Meier-Kriesche,2 C. Larsen.1

    1Emory University, Atlanta; 2Bristol-Myers Squibb, Lawrenceville.

    Purpose: The development of donor-specific antibody (DSA) is linked to an increased risk of antibody-mediated rejection and graft failure. The 3 year intent-to-treat results from…
  • 2015 American Transplant Congress

    Final Results from the BENEFIT-EXT Trial: A 7 Year Follow-Up of Belatacept Treated Patients

    S. Florman,1 J. Medina Pestana,2 M. Rial,3 L. Rostaing,4 D. Kuypers,5 F. Mühlbacher,6 M. Polinsky,7 U. Meier-Kriesche,7 J. Grinyó,8 A. Durrbach.9

    1Mt Sinai Med Ctr, NY; 2Hosp do Rim e Hipertensão, Sao Paulo, Brazil; 3Inst de Nefrologia, Buenos Aires, Argentina; 4Univ Hospital, Toulouse, France; 5Univ Hospital Leuven, Leuven, Belgium; 6Vienna Transplantation Ctr, Vienna, Austria; 7BMS, Lawrenceville; 8Univ Hosp Bellvitge, Barcelona, Spain; 9Univ Hosp of Bicêtre, Villejuif, France.

    Background: At 3 and 5yrs post-transplant, BENEFIT-EXT showed a renal function benefit and consistent safety in belatacept (bela) treated pts vs cyclosporine (CsA). Final 7…
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