2016 American Transplant Congress
Activated Cytoprotective Mechanisms in DBD Kidneys Correlate with Kidney Function in Transplant Recipients: A Study Using Clinical Samples from the UK QUOD Biobank.
The onset of abnormal pathophysiological changes following brain death adversely impact kidney function following transplantation. Understanding the biological mechanisms that affect kidney quality will allow…2016 American Transplant Congress
Normothermic Ex Vivo Liver Perfusion (NEVLP) Using Steen Solution as Preservation Technique for Liver Transplantation-First Clinical Results.
Surgery, Toronto General Hospital, Toronto, Canada.
The European trial investigating NEVLP as preservation technique for liver transplantation uses Gelafusine, a non-FDA approved bovine derived gelatin-based perfusion solution. In contrast, we report…2016 American Transplant Congress
Deceased Organ Donor Management: Does Hospital Volume Matter?
Purpose: Despite the association between hospital volume and outcomes for various diseases, there have been no studies to assess the impact of hospital organ donor…2016 American Transplant Congress
The “PHS Increased Risk” Label Is Associated with Non-Utilization of Hundreds of Organs Per Year.
The Public Health Service (PHS) guidelines use behavioral risk factors to designate certain organ donors as carrying increased risk for the transmission of hepatitis B,…2016 American Transplant Congress
Are We Refusing Good Organs? Outcomes of Ventilator Management of Sub-Optimal Lung Donors.
PurposeOptimizing donor lung function is essential for organ acceptance and successful lung transplantation (LTx). We hypothesized that ventilator management of sub-optimal donor lungs, PaO2<300 mmHg,…2016 American Transplant Congress
Pancreas Transplantation from Pediatric Donors: A UNOS Registry Analysis.
Division of Transplantation, University of Illinois at Chicago, Chicago.
Introduction: Major concerns about the utilization of pediatric pancreata are the cumulative islet mass and the increased technical complexity. The primary aim of this study…2016 American Transplant Congress
Comparison of Three Approaches for Laparoscopic Donor Nephrectomy: Transvaginal, Transumbilical Single Site and Retroperitoneal.
Department of Urology and Renal Transplantation Surgery, Sapporo Hokuyu Hospital, Sapporo, Japan.
Objectives: Reduction of burdens to live kidney donors are important. The aim of this study was to compare the surgical outcomes of 3 approaches we…2016 American Transplant Congress
Erythropoietin (EPO) Mediates Spontaneous Kidney Transplant Tolerance in Mice.
Spontaneous allogeneic kidney transplant tolerance occurs in mice, but the underlying mechanisms are unknown. Building upon recent human data showing that EPO, an erythropoietic hormone…2016 American Transplant Congress
Designing a Novel Highly Selective Immunoproteasome Inhibitor That Promotes Longterm Heart Allograft Acceptance While Inducing Immune Cell Exhaustion, Treg Induction and Memory Cell Suppression.
The constitutive Proteasomes (c-20S) are ubiquitously expressed cellular proteases that degrade polyubiquitinated proteins and regulate cell functions. However, immunoproteasomes (IP or i-20S) are primarily expressed…2016 American Transplant Congress
Tracking of Endogenous Graft-Reactive Tregs Reveals Their Peripheral Enrichment During Transplantation Tolerance.
Purpose: Our goal for this study was to determine the relative fates of endogenous Foxp3- conventional (Tconv) and Foxp3+ regulatory T cells (Tregs) specific for…
American Transplant Congress abstracts