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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Impact of Induction Immunosuppression on Renal Recovery in Adult Liver Transplant Recipients – A Single Center Experience

    T. Zurick1, D. Bruno2, D. Kumar3, R. Winstead1, C. Song1, A. Brown1, S. Sterling1, I. Yakubu1

    1Pharmacy, VCU Health System, Richmond, VA, 2Transplant Surgery, VCU Health System, Richmond, VA, 3Transplant Nephrology, VCU Health System, Richmond, VA

    *Purpose: Renal dysfunction after liver transplantation (LT) is associated with increased morbidity and mortality. Early exposure to calcineurin inhibitors (CNI) is a risk factor for…
  • 2022 American Transplant Congress

    Allocation Based on Acuity Circles Decreases Waiting Time for Liver Transplant Patients

    M. H. Kim, K. Sasaki, A. Gallo, T. Pham, M. L. Melcher, S. Busque, C. Esquivel, C. Bonham

    Stanford University, Stanford, CA

    *Purpose: In February, 2020, UNOS implemented a new liver allocation system incorporating a combination of acuity based on MELD/PELD score and distance from the donor…
  • 2022 American Transplant Congress

    Outcomes of Hlai Kidney Transplants in Patients with Cpra 100% After Desensitization

    A. A. Vo1, J. Tang1, S. Williamson1, C. Meyers1, E. Huang1, X. Zhang2, M. Haas3, A. Peng1, R. Najjar1, S. Supreet1, N. Ammerman1, K. Lim1, M. Gillespie1, N. Badash1, S. Jordan1

    1Comprehensive Transplant Center, Cedars Sinai Medical Ctr, Los Angeles, CA, 2HLA Laboratory, Cedars Sinai Medical Ctr, Los Angeles, CA, 3Pathology, Cedars Sinai Medical Ctr, Los Angeles, CA

    *Purpose: The KAS implementation was aimed at increasing access to kidney transplantation in highly HLA sensitized (HS) patients. However, combining desensitization (DES) + KAS could…
  • 2022 American Transplant Congress

    Impact of Glecaprevir/Pibrentasvir on Tacrolimus Concentration in Solid Organ Transplant Recipients with or without Triazole Antifungal Therapy

    D. Abraham1, A. Feist2, N. Law1, S. Aslam1, V. Nguyen1

    1University of California San Diego Health, San Diego, CA, 2University of California San Diego, San Diego, CA

    *Purpose: Provide guidance on tacrolimus (TAC) dose adjustments during glecaprevir/pibrentasvir (GLE/PIB) initiation and discontinuation in patients on triazole antifungals by comparing changes in TAC concentration-dose…
  • 2022 American Transplant Congress

    Identification of a Human B Cell State with Allogeneic Antigen Cross-Presenting Potential

    U. Bhatia, E. C. Guinan

    Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA

    *Purpose: B cells are known to play a significant role in allograft tolerance or rejection, largely determined by production of cytokines and antibodies that suppress…
  • 2022 American Transplant Congress

    Survival Comparison of Simultaneous Pancreas-Kidney Transplant with Pancreas After Living-Donor Kidney Transplant by Wait Time and Organ Quality

    G. R. Lyden1, E. S. Helgeson2, E. B. Finger3, A. J. Matas3, J. J. Snyder4, D. M. Vock2

    1Scientific Registry of Transplant Recipients, Hennepin Healthcare Research Institute; Division of Biostatistics, University of Minnesota, Mpls, MN, 2Div Biostatistics U MN, Mpls, MN, 3Dept Surg U MN, Mpls, MN, 4Hennepin Healthcare Research Institute, Mpls, MN

    *Purpose: The survival benefit of simultaneous pancreas-kidney (SPK) compared to pancreas after living-donor kidney (PALK) transplant is controversial. Wait times for SPK and donor risk…
  • 2022 American Transplant Congress

    Antibody Response to 3-Dose SARS-CoV-2 mRNA Vaccination in Pediatric Solid Organ Transplant Recipients

    C. X. Qin1, S. R. Auerbach2, O. Charnaya1, L. A. Danziger-Isakov3, N. H. Ebel4, A. G. Feldman2, E. K. Hsu5, J. McAteer1, S. Mohammad6, E. R. Perito7, A. M. Thomas1, T. P. Chiang1, J. M. Garonzik-Wang1, D. L. Segev1, D. B. Mogul1

    1Johns Hopkins University, Baltimore, MD, 2University of Colorado, Aurora, CO, 3University of Cincinnati, Cincinnati, OH, 4Stanford University, Palo Alto, CA, 5University of Washington, Seattle, WA, 6Northwestern University, Chicago, IL, 7University of California San Francisco, San Francisco, CA

    *Purpose: We report the immunogenicity and safety of a third BNT162b2 vaccine in pediatric solid organ transplant recipients (pSOTRs).*Methods: Samples from pSOTRs (12-18 years) enrolled…
  • 2022 American Transplant Congress

    Molecular ABO Typing: An Effective Tool for Resolving Deceased Donor Indeterminate ABO Types

    D. Tanglao1, S. S. Musa1, J. J. Chew1, L. Santiago2, K. Herron3, B. O'Neale3, N. A. Lemp1, S. O. Dionne4

    1Eurofins DPT, Los Angeles, CA, 2Eurofins DPT, Centennial, CO, 3Eurofins DPT, Centennial, CA, 4Eurofins DPT, denver, CO

    *Purpose: In order to evaluate molecular ABO typing as an alternative method of blood typing that may be employed when indeterminate serological typing results are…
  • 2022 American Transplant Congress

    Fibrin Deposition in Ischemic Damaged Liver Grafts and Reconditioning with Thrombolytic Therapy During Normothermic Machine Perfusion

    T. Goto, Y. Noguchi, S. Ganesh, B. Arulratnam, M. Kawamura, C. Parmentier, S. Ray, T. Reichman, N. Selzner, M. Selzner

    Ajmera Transplant Program, Department of Surgery, Toronto General Hospital, University Health Network, Toronto, ON, Canada

    *Purpose: Normothermic ex situ perfusion (NMP) is a novel technique for the storage and assessment of marginal livers retrieved from donors after circulatory death (DCD).…
  • 2022 American Transplant Congress

    Health Care Transition of Adolescents After Kidney Transplantation in Germany and Austria – The Randomized Controlled Transnephro Trial

    L. Pape1, M. Kreuzer1, A. Großhenig2, J. Prüfe1, S. Group3

    1Pediatrics II, University Hospital of Essen, Essen, Germany, 2Biostatistics, Hannover Medical School, Hannover, Germany, 3German Society of Pediatric Nephrology, Berlin, Germany

    *Purpose: Adolescence is the age with the highest rate of graft losses because of non-adherence and the transfer from pediatric to adult care. Health care…
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