Abstracts Archive - Page 130 of 1683 - ATC Abstracts

2022 American Transplant Congress
Escalating Waitlist Mortality Above MELD 40: A Rationale to Uncap MELD 3.0?
A. Kwong, A. Mannalithara, W. Kim
Division of Gastroenterology and Hepatology, Stanford University, Stanford, CA
*Purpose: MELD 3.0 is a recently proposed model that improves upon MELD-Na, incorporating sex and albumin as additional variables, updating existing coefficients and adding relevant…
2022 American Transplant Congress
Surging Liver Transplant Rates for Alcohol-Associated Liver Disease May Exacerbate Waitlist Death of Patients with Hepatocellular Carcinoma in MMAT-3 Era
L. Yuan¹, J. L. Dodge¹, K. Zhou¹, N. Terrault²
¹Division of Gastrointestinal and Liver Diseases, University of Southern California, Los Angeles, CA, ²University of Southern California, Los Angeles, CA
*Purpose: Rates of liver transplantation (LT) for alcohol-associated liver disease (ALD) have increased significantly, in part related to broader acceptance of severe alcohol hepatitis (AH)…
2022 American Transplant Congress
Cd137 on Host Dendritic Cells Fine-Tunes the Intesity of Donor T Cells in Systemic Alloinmmune Responses
S. Park¹, H. Cho², B. Kwon³, J. Lee⁴, H. Park¹, J. Park⁴, K. Park⁴, K. Yoo⁴
¹Department of Surgery, University of Ulsan College of Medicine, Ulsan, Korea, Republic of, ²University of Ulsan College of Medicine, Ulsan, Korea, Republic of, ³School of Biological Sciences, University of Ulsan, Ulsan, Korea, Republic of, ⁴Department of Internal Medicine, University of Ulsan College of Medicine, Ulsan, Korea, Republic of
*Purpose: CD137 is a potent costimulatory receptor for CD8+ T cells but it also regulates dendritic cells (DCs) to suppress immune responses. In this study,…
2022 American Transplant Congress
The Impact Of Covid-19 On Pediatric Organ Donation And Transplantation
E. Lee¹, X. Zhang², G. Mazariegos³, T. Nakagawa⁴
¹Transplant Surgery, UPMC Childrens Hospital of Pittsburgh, Pittsburgh, PA, ²UPMC Thomas E. Starzl Transplantation Institute, Pittsburgh, PA, ³Children's Hospital of Pittsburgh, Pittsburgh, PA, ⁴Department of Pediatrics, Division of Pediatric Critical Care Medicine, University of Florida College of Medicine, Jacksonville, FL
*Purpose: The global COVID-19 pandemic has significantly altered delivery of healthcare. Hospital resource utilization has been impacted on multiple levels including solid organ transplantation and…
2022 American Transplant Congress
Increasing Proportion of High-Risk Cytomegalovirus (CMV) Donor Positive/recipient Negative (D+R-) Serostatus in Solid Organ Transplant Recipients (SOTRs)
H. Imlay¹, M. M. Wagener², N. Singh², A. P. Limaye³
¹University of Utah, Salt Lake City, UT, ²University of Pittsburgh, Pittsburgh, PA, ³University of Washington, Seattle, WA
*Purpose: CMV D+R- serostatus is independently associated with worse long-term graft and patient survival across many organ transplant types despite current prevention and treatment strategies.…
2022 American Transplant Congress
HCK is a Key Regulator for Macrophage Polarization in Kidney Fibrosis
C. Wei, M. Chen, Z. Sun, Z. Yi, C. He, W. Zhang
Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: Interstitial fibrosis and tubular atrophy (IF/TA) is common histological abnormality in biopsy of kidney transplants. Our previous study from a prospective human kidney transplant…
2022 American Transplant Congress
Long-Term Outcomes of Liver Transplantation (LT) Using Grafts from Donors with Active and Chronic Hepatitis B Virus (HBV) Infection; Multi-Center Cohort Study
S. Suh¹, S. Gang², Y. Choi², S. Hong², N. Yi², K. Lee², K. Suh²
¹Chung-Ang University, Seoul, Korea, Republic of, ²Seoul National University, Seoul, Korea, Republic of
*Purpose: Liver grafts from donors with hepatitis B infection contributed to expand the donor pool under the Hepatitis B immunoglobulin (HBIG) and antiviral agents (NA:…
2022 American Transplant Congress
Cost-Effectiveness of Transplanting Hepatitis C Donor Hearts Into Hepatitis C Uninfected Recipients
A. R. Gandhi¹, A. E. Woolley², L. R. Baden², M. M. Givertz², M. L. Jones¹, J. Kim³, H. R. Mallidi², M. R. Mehra², A. M. Neilan¹
¹Massachusetts General Hospital, Boston, MA, ²Brigham and Women's Hospital, Boston, MA, ³Harvard T.H. Chan School of Public Health, Boston, MA
*Purpose: To examine the clinical impact and cost-effectiveness of hepatitis C viremic (HCV+) heart organ donation in the United States.*Methods: We used a microsimulation model…
2022 American Transplant Congress
18 Month Impact of the National Liver Review Board
J. Foutz¹, S. Noreen¹, K. Bradbrook², M. Cafarella¹, J. Pomposelli³, S. Biggins⁴, J. Trotter⁵
¹United Network for Organ Sharing, Richmond, VA, ²Research, United Network for Organ Sharing, Richmond, VA, ³University of Colorado, Aurora, CO, ⁴University of Washington, Seattle, WA, ⁵Baylor University Medical Center, Dallas, TX
*Purpose: The National Liver Review Board (NLRB) was implemented 5/14/2019, establishing a national structure for liver exceptions comprised of three specialty review boards and a…
2022 American Transplant Congress
Antibody Response to 3-Dose SARS-CoV-2 mRNA Vaccination in Pediatric Solid Organ Transplant Recipients
C. X. Qin¹, S. R. Auerbach², O. Charnaya¹, L. A. Danziger-Isakov³, N. H. Ebel⁴, A. G. Feldman², E. K. Hsu⁵, J. McAteer¹, S. Mohammad⁶, E. R. Perito⁷, A. M. Thomas¹, T. P. Chiang¹, J. M. Garonzik-Wang¹, D. L. Segev¹, D. B. Mogul¹
¹Johns Hopkins University, Baltimore, MD, ²University of Colorado, Aurora, CO, ³University of Cincinnati, Cincinnati, OH, ⁴Stanford University, Palo Alto, CA, ⁵University of Washington, Seattle, WA, ⁶Northwestern University, Chicago, IL, ⁷University of California San Francisco, San Francisco, CA
*Purpose: We report the immunogenicity and safety of a third BNT162b2 vaccine in pediatric solid organ transplant recipients (pSOTRs).*Methods: Samples from pSOTRs (12-18 years) enrolled…