ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Concomitant Proton Pump Inhibitor and Mycophenolate Mofetil Use in Renal Transplant Recipients.

    K. Patel,1 B. Stephany,2 J. Barnes,1 S. Bauer,1 M. Spinner.1

    1Department of Pharmacy, Cleveland Clinic, Cleveland, OH; 2Department of Nephrology and Hypertension, Cleveland Clinic, Cleveland, OH.

    Pharmacokinetic (PK) data show reduced mycophenolic acid levels in transplant recipients taking mycophenolate mofetil (MMF) and proton pump inhibitors (PPIs) concomitantly. MMF dosing is not…
  • 2016 American Transplant Congress

    Mycophenolate Mofetil Dose Reduction Are Associated with the Risk of Acute Rejection and Graft Failure After Renal Transplantation.

    A. El-Agroudy,1 A. Taher,2 A. Alaradi,2 B. Alhayki,2 S. Gareeb,2 E. Farid.2

    1Internal Medicine, College of Medicine, Arabian Gulf University, Manama, Bahrain; 2Nephrology, Salmaniya Medical Complex, Manama, Bahrain.

    Background: Mycophenolate mofetil (MMF) is a highly effective immunosuppressive agent in transplant therapy. Although MMF is generally well tolerated, optimal therapy may be limited by…
  • 2016 American Transplant Congress

    Do Powerful Induction Antibodies Increase Post Renal Transplant Infections?

    M. John, I. Dortonne, B. Kim, C. Li, M. Killackey, A. Paramesh, B. Lee, R. Zhang, G. Parker, J. Buell.

    Transplant Institute, Tulane University School of Medicine, New Orleans, LA.

    Purpose: Infection is one of the most common and costly complications of solid organ transplantation. Alemtuzemab (AL) is a powerful antibody that significantly reduced rejection…
  • 2016 American Transplant Congress

    Anti-Thymocyte Globulin Induced Thrombocytopenia and Bleeding After Kidney Transplantation.

    M. Dokus,1 A. Patel,1 J. Iuppa,2 E. Venniro,3 A. Danzig,1 J. Cooley,2 J. Taylor,3 R. Kashyap,1 M. Orloff.1

    1Department of Surgery, Division of Transplant and Hepatobiliary Surgery, University of Rochester, Rochester, NY; 2Department of Pharmacy, University of Rochester, Rochester, NY; 3Department of Medicine, Division of Nephrology, University of Rochester, Rochester, NY.

    Background: Bleeding is a significant challenge after renal transplantation. Anti-thymocyte globulin (ATG) induced thrombocytopenia may increase bleeding after kidney transplantation (KTx), but this association has…
  • 2016 American Transplant Congress

    Diabetes Mellitus and Kidney Transplant Outcomes.

    A. Mehrnia,1 A. Wang,1 W. Chaiwatcharayut,2 E. Huang,1 S. Bunnapradist.1

    1Nephrology, University of California-Los Angeles, Los Angeles, CA; 2Internal Medicine, Albert Einstein University, Bronx, NY.

    Background:This study investigates the impact of pre-existing (PDM) and new onset diabetes (NODAT) on the graft and patient survival after kidney transplant.Methods:The UNOS database was…
  • 2016 American Transplant Congress

    The Incidence of Symptomatic Pericardial Effusion with Long-Term Sirolimus Therapy.

    N. Chandolias,1 S. Wang,1 A. Hahn,1 R. Lyubarova,2 R. Lopez-Soler,1 D. Conti.1

    1Surgery, Albany Medical College, Albany, NY; 2Cardiology, Albany Medical College, Albany, NY.

    BACKGROUNDSirolimus is an approved agent for immunosuppressive therapy after renal transplantation. Pericardial effusion and tamponade have been recognized as potentially serious complications of long-term sirolimus…
  • 2016 American Transplant Congress

    Outcomes from De Novo Tacrolimus Weight-Based Dosing Compared to Conservative Dosing in Kidney Transplant Recipients.

    B. Summers,2 K. Szempruch,1 M. Harris,2 A. Quidley,1 C. Haisch,1 A. Maldonado.1

    1Vidant Medical Center/East Carolina University, Greenville, NC; 2Duke University Hospital, Durham, NC.

    Purpose: To compare de novo tacrolimus (TAC) weight based dosing (WDG) and conservative dosing (CDG) on incidence and duration of DGF in adult kidney transplant…
  • 2016 American Transplant Congress

    Effect of Inflammation on Concentration of Intracellular Tacrolimus.

    E. Bae,1 S. Yang,2 S. Han,1 J.-Y. Park,1 H. Lee,1 Y. Kim.1

    1Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea; 2Kidney Research Institute, Seoul National University, Seoul, Republic of Korea.

    Background: The use of calcineurin inhibitors improved the outcome for transplant recipients. However, acute rejection (AR) and infection remained still an unsolved problem. We evaluated…
  • 2016 American Transplant Congress

    Evaluation of the Utilization of Filgrastim in Kidney Transplant Recipients.

    T. Poon,1 C. Guerra.2

    1Pharmacy, Long Island University, Brooklyn, NY; 2Pharmacy, SUNY Downstate Medical Center, Brooklyn, NY.

    Purpose: Granulocyte colony-stimulating factors (G-CSF), such as filgrastim, stimulate the production, proliferation, and differentiation of neutrophils and are indicated for the treatment of neutropenia in…
  • 2016 American Transplant Congress

    Social Support Does Not Predict Medication Adherence Post-Transplantation: A Systematic Review and Meta-Analysis.

    K. Ladin,1 A. Daniels,1 R. Bannuru,2 M. Osani.2

    1Occupational Therapy, Tufts University, Medford, MA; 2Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA; 3Division of Rheumatology, Tufts Medical Center, Boston, MA.

    Background: Although social support is used to determine eligibility, the relationship between social support and nonadherence remains unclear. We examined the predictive value of social…
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