2016 American Transplant Congress
Immune Tolerance Monitoring in Renal Allograft Tolerance Induced by Transient Mixed Chimerism in Nonhuman Primates and Humans.
Center for Transplantation Science, Massachusetts General Hospital, Boston, MA.
Background: Successful induction of allograft tolerance in MHC-mismatched kidney transplantation has been achieved after induction of transient chimerism in both nonhuman primates (NHP) and humans.…2016 American Transplant Congress
IL-10 Expression of In Vitro Activated B Cells as A Biomarker for B Cell Tolerance.
Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA.
Background: A significant role for regulatory B cell has been suggested in kidney transplant recipients who achieved operational tolerance while receiving conventional immunosuppression. We studied…2016 American Transplant Congress
Acquired Down-Regulation of B Cell Function Induced by Donor Blood Group Antigens After ABO-Incompatible Kidney Transplantation.
Background: The long-term of B cell immunobiology against donor blood group antigen has not been elucidated in ABO incompatible kidney transplantation (ABOi KTx).Methods: The antibody…2016 American Transplant Congress
Three-Year Outcome After HSCT with Subsequent KT from the Same Haploidentical Donor without Immunosuppression.
Allogeneic hematopoietic stem cell transplantation (HSCT) can lead to donor-specific tolerance. Patients reported in the literature that underwent kidney transplantation (KT) after a previous HSCT…2016 American Transplant Congress
Memory Regulatory T Cell: A Potential Actor in Immunological Operational Tolerance in Kidney-Transplant Patients via the ATP Degradation into Adenosine.
Regulatory T cells (Tregs) are essential actors in the control of self-tolerance and exacerbated inflammation. In experimental transplantation Tregs are critical to achieve alloantigen tolerance…2016 American Transplant Congress
Clinical and Immunologic Assessments of Immune Responses in a Liver Transplant Patient with CD40L Deficiency and Hyper IgM Syndrome.
Introduction: Monoclonal antibodies that disrupt CD40/CD40 ligand (CD40L) interactions are likely to have utility in human transplantation. However, the extent of the immunosuppressive effects of…2016 American Transplant Congress
Trends in Aspergillus Infection After Liver Transplantation, 1988-2014.
Background: Invasive Aspergillosis is an important cause of morbidity and mortality in liver transplant recipients. Aspergillus may account for up to 25% of all fungal…2016 American Transplant Congress
Circulating miR-215, miR-let-7c miR-154, miR-193a, NR_036506.1 and NR_027669.1 as Biomarkers Predict Fungal Infection in Post-Transplanted Recipients.
Aims: The incidence of fungal infection in post-transplanted patients is 13%-17%, which seriously effecting perioperative survival and increasing their economic burden. We wanted to find…2016 American Transplant Congress
Late-Onset Pneumocystis Jirovecii Pneumonia After Renal Transplantation: A Case-Control Study.
BackgroundPneumocystis jirovecii pneumonia (PCP) usually occurs during the first year after solid organ transplantation. Introduction of routine prophylaxis have reduced the incidence of PCP drastically.…2016 American Transplant Congress
Pneumocystis Pneumonia Following Solid Organ Transplantation, Systematic Review and Meta-Analysis.
Background: Different variables have been reported that may increase the risk of pneumocystis pneumonia (PCP) in solid organ transplant patients (SOT).Objectives:To investigate the effect of…
American Transplant Congress abstracts