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  • 2016 American Transplant Congress

    An Assurance of Insurance: Should Living Kidney Donors Be Required to Have Health Insurance?

    J. Siegel,1 A. Humar,2 P. Gianaros,1 J. Steel.2

    1Department of Psychology, University of Pittsburgh, Pittsburgh, PA; 2Department of Surgery, Division of Transplantation, University of Pittsburgh, Pittsburgh, PA.

    Lack of health insurance has been related lack of access to health care, poorer health, and increased mortality. In this study, we investigate sociodemographic predictors…
  • 2016 American Transplant Congress

    Urinary Neutrophil Gelatinase-Associated Lipocalin in Living Kidney Donor Nephrectomy.

    Y. Yoon,1 H. Lee,1 D. Joo,2 K. Huh,2 M. Kim,2 S. Kim,2 Y. Kim,2 W. Han.1

    1Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea; 2Transplantation Surgery, Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Republic of Korea.

    Introduction: Urinary neutrophil gelatinase-associated lipocalin (uNGAL) is a marker for acute kidney injury. This study was conducted to evaluate the efficacy of perioperative uNGAL in…
  • 2016 American Transplant Congress

    Ex-Vivo Normothermic Perfusion for Assessment of High Risk Deceased Donor Kidneys for Transplantation.

    S. Kabagambe, I. Palma, Y. Smolin, T. Boyer, I. Palma, J. Sageshima, C. Santhanakrishnan, C. Troppmann, J. McVicar, R. Perez.

    Surgery, University of California-Davis, Sacramento, CA.

    Despite the organ shortage, many procured deceased donor kidneys are deemed too high risk for failure and discarded. Ex-vivo normothermic perfusion (EVNP) may be useful…
  • 2016 American Transplant Congress

    Predicting Delayed Kidney Graft Function with Gene Expression in Preimplantation Biopsies.

    T. Mourão,1,3 K. Mine,1 E. Campos,1,3 J. Medina-Pestana,2,3 H. Tedesco-Silva,2 M. Gerbase-De Lima.

    1Immunogenetics Institute, Associação Fundo de Incentivo à Pesquisa - AFIP, São Paulo, SP, Brazil; 2Hospital do Rim e Hipertensão, Fundação Oswaldo Ramos, São Paulo, SP, Brazil; 3UNIFESP, São Paulo, SP, Brazil.

    Aiming to further the investigation of markers in pre-implantation biopsies (PIB) for the prediction of delayed graft function (DGF), we analyzed, in a different cohort…
  • 2016 American Transplant Congress

    Predictive Model of Delayed Graft Function in Machine Perfused Kidney Transplantation: Model Validation Using Decision Curve Analysis.

    K. Ravindra,1 S. Sanoff,1 D. Vikraman,1 U. Patel,1 M. Ellis,1 E. Squires,2 D. Sudan,1 W. Irish.1

    1Surgery, Duke University, Durham, NC; 2Half Moon Bay, Raleigh.

    Introduction: Predictive model for delayed graft function (DGF) was developed (Am J Transpl 2010; 10: 2279–86)excluding organs that were machine perfused (MP). Currently, approximately 50%…
  • 2016 American Transplant Congress

    The Use of Kidneys with Acute Kidney Injury: The Good, the Bad and the Ugly.

    C. Boffa,1,2 F. van de Leemkolk,1 E. Curnow,3 J. Gilbert,2 E. Sharples,1,2 R. Ploeg.1,2

    1Nuffield Department of Surgical Sciences, Oxford University, Oxford, United Kingdom; 2Oxford Transplant Centre, Oxford University Hospital Trust, Oxford, United Kingdom; 3Department of Statistics, NHS Blood and Transplant, Bristol, United Kingdom.

    Introduction:The widening gap between supply and demand in kidney transplantation has lead to the increased use of kidneys from marginal donors, including those with acute…
  • 2016 American Transplant Congress

    Hydrogen Sulfide Supplementation Helps Mitigate Effects of Ischemia Reperfusion Injury in a Murine Model of Donation After Cardiac Death Renal Transplantation.

    J. Grewal,1 I. Lobb,1 M. Saha,2 J. Jiang,2 A. Haig,1 A. Sener.1,2

    1Microbiology & Immunology, University of Western Ontario, London, Canada; 2Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, London, Canada.

    Donation after cardiac death(DCD) renal grafts experience a combination of prolonged warm and cold ischemia leading to greater ischemia reperfusion injury(IRI) that results in higher…
  • 2016 American Transplant Congress

    Markers of Activation of Microvascular Endothelial Cells Predict a Poor Long-Term Graft Outcome in Early Renal Graft Biopsies Displaying Acute Tubular Necrosis.

    Y.-C. Dubois-Xu,1 P. Ahmadpoor,1 A. Corchia,1 D. Buob,2 P. Galichon,1 I. Brochériou,1 C. Suberbielle,3 A. Hertig,1 E. Rondeau.1

    1INSERM UMR_S1155, INSERM, Paris, France; 2Pathology, APHP, Hoptal Tenon, Paris, France; 3HLA Institute, INSERM_S940, Paris, France.

    Acute tubular necrosis (ATN), is a histopathological feature frequently seen in the early post renal transplant biopsies taken from patients with delayed graft function (DGF).…
  • 2016 American Transplant Congress

    The Influence of Static versus Machine Dynamic Perfusion Kidney Graft Preservation on Delayed Graft Function Incidence: A Prospective, Randomized Study.

    H. Marinho Neto, V. Aires, J. Offerni, W. Luconi, P. Luconi, S. Braga, I. Noronha, R. Barsante, J. Moreira, A. Savina, L. Kuschnaroff, F. Lemos, A. Cuvello, P. Chocair, L. Moura, A. Silva Filho, I. Charpiot, M. Abbud Filho, M. Cunha, P. Malafonte, D. Demetrio, L. Miorin, A. Duboc Filho, A. Claudini, W. Aguiar, H. Tedesco, J. Medina Pestana.

    Organ Procurement Organization, Kidney Hospital, São Paulo, Brazil.

    Introduction: The incidence of delayed graft function (DGF) in Brazilians deceased kidney donor receptors is high; this is attributed to poor hemodynamic conditions on potential…
  • 2016 American Transplant Congress

    Hypothermic Machine Perfusion Ameliorates Vasospasm and Edema of Podocytes and Renal Tubular Epithelial Cells Through Upregulating Expression of Krüppel-Like Factors 2.

    Z. Zhong,1 D. Ko,2 Y. Wang,1 Q. Ye.1

    1Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Wuhan, Hubei, China; 2Massachusetts General Hospital, Department of Urology, Harvard Medical School, Boston, MA.

    Protective mechanisms of hypothermic machine perfusion (MP) remain largely unknown. Vascular branches of the renal arteries of 6 kidneys in 320 donors were unexpectedly injured…
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