ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Extreme Hyperoxia During Pre-Implant Normothermic Liver Perfusion (PINLiP) Is Associated with Post-Reperfusion Syndrome and Vasoplegia.

    C. Watson, V. Kosmoliaptsis, L. Randle, M. Hamed, J. Klinck, A. Butler.

    Cambridge Transplant Unit, Addenbrookes Hospital, Cambridge, United Kingdom.

    In response to the increasing number of DCD and marginal DBD donor livers, we started a programme of pre-implant normothermic perfusion (PINLiP) to enable functional…
  • 2016 American Transplant Congress

    Trends in Liver Transplant Rates and Waitlist Survival.

    M. Bowring, A. Massie, X. Luo, L. Kucirka, E. Chow, A. Cameron, D. Segev.

    JHU, Baltimore.

    Long term changes in access to deceased-donor liver transplantation(DDLT) due to persistent growth of the waitlist, stagnant organ availability, and intermittent allocation policy changes have…
  • 2016 American Transplant Congress

    Impact of Left Ventricular Diastolic Dysfunction on Patients Being Evaluated for Liver Transplantation.

    K. Forde,1 R. McLean,1 W. O'Donnell,1 K. Krok,2 M. Patel,1 G. Lin,3 J. Oh,3 M. Krowka,3 M. Fallon,4 S. Kawut.1

    1Medicine, University of Pennsylvania, Philadelphia, PA; 2Medicine, Penn State Hershey, Hershey, PA; 3Medicine, Mayo Clinic, Rochester, MN; 4Medicine, University of Texas Medical School – Houston, Houston, TX.

    IntroductionDiastolic dysfunction (DD) is the cardinal finding in cirrhotic cardiomyopathy, a condition in patients with liver disease that is associated with an increased risk of…
  • 2016 American Transplant Congress

    Does Rising MELD Score Convey Worse Liver Transplant Outcome?

    A. Rahnemai-Azar, J. Perkins, M. Montenovo, T. Pearson, R. Bakthavatsalam, S. Rayhill, A. Dick, J. Reyes, L. Sibulesky.

    Surgery, University of Washington, Seattle, WA.

    Since February 2002, the Model for End-Stage Liver Disease (MELD) score has been used to allocate liver allografts in the U.S. The aim of this…
  • 2016 American Transplant Congress

    Fifty Is the New 40? An Argument to Uncap the MELD Score.

    J. DiNorcia,1 Y. Genyk,1 K. Andreoni,4 W. Kim,3 J. Levitsky,5 D. Mulligan,6 R. Sung,7 M. Nadim.1

    1Univ of Southern California, Los Angeles, CA; 2Stanford University, Palo Alto, CA; 3Univ of Florida, Gainesville, FL; 4Northwestern Univ, Chicago, IL; 5Yale Univ, New Haven, CT; 6Univ of Michigan, Ann Arbor, MI.

    Background: The MELD score is used to prioritize patients awaiting liver transplantation (LT) and has been capped at 40 to prevent transplant futility in patients…
  • 2016 American Transplant Congress

    Waitlist versus Population-Based Metrics of Access to Liver Transplantation: Comparing UNOS Waitlist Data and Nationally-Representative Data of Patients with End-Stage Liver Disease.

    D. Goldberg,1,2 B. French,2 J. Lewis,1,2 S. Halpern.1,2

    1Department of Medicine, University of Pennsylvania, Philadelphia, PA; 2Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA.

    Background: Strategies for allocating transplantable livers are evaluated based on how they impact waitlisted patients. This approach may not optimize outcomes for all patients with…
  • 2016 American Transplant Congress

    Role of Donor Hemodynamic Trajectory in Determining Graft Survival in Liver Transplantation from Donation After Circulatory Death Donors.

    D. Firl, K. Hashimoto, C. O'Rourke, J. Fung, B. Eghtesad.

    Cleveland Clinic, Cleveland.

    This retrospective study of 87 donation after circulatory death (DCD) liver transplants from 2007-2015 tested the hypothesis that donor hemodynamic trajectory following withdrawal effects graft…
  • 2016 American Transplant Congress

    The Impact of Gender Discordance on Graft Survival Among Liver Transplant Recipients.

    J. Moore, X. Luo, A. Massie, T. Purnell, D. Mogul, D. Segev.

    Johns Hopkins School of Medicine, Baltimore.

    Past studies have shown inferior liver graft survival in gender-discordant recipient/donor pairings compared to gender-matched pairings, particularly in male recipients of female donor livers. However,…
  • 2016 American Transplant Congress

    Underweight BMI Is Associated with Graft Failure and Increased Mortality in Liver Transplant Recipients.

    T. Alhamad,1 N. Carlsson,2 X. Liu,3 J. Wellen,4 J. Garonzik-Wang,4 S.-H. Chang.2

    1Renal Division, Department of Internal Medicine, Washington University in St. Louis, St. Louis; 2 Division of Public Health Sciences, Department of Surgery, Washington University in St. Louis, St. Louis; 3Division of Biostatistics, Washington University in St. Louis, St. Louis; 4Department of Surgery, Washington University in St. Louis, St. Louis.

    Background:Malnutrition and sarcopenia have been associated with inferior outcomes after liver transplantation. However, little is known about the differential impact of underweight on outcomes based…
  • 2016 American Transplant Congress

    Liver Transplantation in Patients Actively Drinking Less Than 6 Months Before Transplant Presenting with Acute Decompensation: A Single-Center Experience.

    H. Monsour, D. Victor, M. Boktour, J. Galati, J. Ontiveros, L. Theriot, R. McFadden, C. Mobley, A. Saharia, S. Gordon-Burroughs, A. Gaber, R. Ghobrial.

    Sherrie and Alan Conover Center for Liver Disease and Transplantation, Houston Methodist Hospital, Houston, TX.

    Background: Alcohol is amongst the leading causes of liver disease worldwide. Most centers have a 6-month abstinence requirement before transplantation candidacy. Mortality rates for acute…
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