ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    DSA After Transplant Increases Risk of Renal Allograft Failure Independent of Concurrent Biopsy Results: The DEKAF Study Data.

    J. Cecka,1 J. Grande,2 F. Cosio,2 R. Leduc,3 The DeKAF Study Group.

    1UCLA Immunogenetics Center Department of Pathology, University of California-Los Angeles, Los Angeles, CA; 2Department of Lab Medicine & Pathology, Mayo Clinic College of Medicine, Rochester, MN; 3Department of Biostatistiscs, University of Minnesota School of Public Health, Minneapolis, MN.

    Donor-specific HLA antibodies (DSA) are a major cause of renal allograft dysfunction and loss following transplant. The presence of DSA, with or without C4d deposition,…
  • 2016 American Transplant Congress

    Immunogenic HLA-DR Eplet Mismatches as Predictors of Transplant Glomerulopathy.

    D. Blum,1 K. Tinckam,2 M. Marrari,3 J. Kim,2 R. Sapir-Pichhadze.1

    1McGill University, Montreal, Canada; 2University Health Network, Toronto, Canada; 3University of Pittsburgh Medical Center, Pittsburgh.

    BackgroundThe number of HLA-DR eplet mismatches (eplet load) is a risk factor for the development of anti-HLA antibodies and transplant glomerulopathy (TG). In the case…
  • 2016 American Transplant Congress

    Association of Ultrastructural Changes in Renal Allograft Biopsies with Antibody-Mediated Rejection (AMR) and Graft Outcomes.

    A. Haririan,1 M. Chaudhry,2 J. Papadimitriou,2 N. Costa,1 B. Thomas,1 M. Mavanur,1 R. Ugarte,1 C. Cangro,1 C. Drachenberg.2

    1Dept of Medicine, Unniversity of Maryland, Baltimore, MD; 2Dept of Pathology, University of Maryland, Baltimore, MD.

    The role of electron microscopy (EM) in diagnosis of AMR is not well-defined. We sought to examine the EM findings in 796 biopsies from 622…
  • 2016 American Transplant Congress

    Antibody Mediated Rejection and Mixed Acute Rejection: Long Term Results and Predictive Factors for Graft Loss Following Proteasome Inhibitor Therapy.

    A. Lichvar,1 A. Leino,1 S. Tremblay,1 B. Abu-Jawdeh,1 A. Govil,1 G. Mogilishetty,1 M. Cardi,2 J. Kremer,2 M. Cuffy,1,2 F. Paterno,1 A. Shields,1,2 D. Witte,1 R. Alloway,1 E. Woodle.1

    1U of Cincinnati, Cincinnati; 2The Christ Hospital, Cincinnati.

    Purpose: Proteasome inhibitor (PI) therapy has been increasingly used to treated antibody mediated rejection (AMR) and mixed acute rejection (MAR). The purpose of this study…
  • 2016 American Transplant Congress

    Evaluation of the Toxicity Profile of Proteasome Inhibitor-Based Therapy for Antibody Mediated Rejection.

    A. Leino,1 A. Lichvar,1 B. Abu-Jawdeh,1 A. Govil,1 G. Mogilishetty,1 M. Cardi,2 J. Kremer,2 M. Cuffy,1 F. Paterno,1 R. Alloway,1 A. Shields,1,2 E. Woodle.1

    1U of Cinncinati, Cincinnati; 2The Christ Hospital, Cincinnati.

    Background: Experience with bortezomib (BTZ) antibody mediated rejection (AMR) therapy has progressively increased over the past few years. The BTZ toxicity profile in the transplant…
  • 2016 American Transplant Congress

    Potential Kidney Donors with Asymptomatic Micorsocpic Hematuria: Histopathological Findings & Outcomes.

    E. Hassan,1,2 H. Aleid,1 T. Zulfiquar,1 I. Ibrahim,1,3 H. Almana.4

    1Department of Kidney & Pancreas Transplantation, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia; 2Department of Nephrology, Fayoum University, Fayoum, Egypt; 3Department of Nephrology, Cairo University, Cairo, Egypt; 4Department of Anatomic Pathology, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.

    Background: Microscopic hematuria is not uncommon in potential kidney donors. After excluding urological causes, most of these donors require kidney biopsy to exclude glomerular lesions.…
  • 2016 American Transplant Congress

    Pre-Donation Weight Loss Postpones Living Kidney Donation without Attaining the Desired Weight Maintenance in the Midterm.

    P. Ventura-Aguiar, E. De Sousa-Amorim, J. Campistol, F. Diekmann, F. Oppenheimer, I. Revuelta.

    Renal Transplant Unit, Hospital Clinic, Barcelona, Spain.

    Pre-donation weight loss in living kidney donation has two main objectives: reduce surgical risk, and decrease long-term complications from obesity and glomerular hypertrophy secondary to…
  • 2016 American Transplant Congress

    Motivation and Stress Associated with Non-Directed Kidney Donation.

    J. Wiseman,1 D. Berglund,1 C. Jacobs,1 D. Larson,1 C. Garvey,1 M. Vogues, S. Rein,1 O. Sanchez,1 C. Radecki Breitkopf,2 H. Ibrahim,1 A. Matas.1

    1U of MN, Mpls; 2Mayo Clinic, Rochester.

    Background: Nondirected kidney donors (NDDs) are unique in that they have the risks of nephrectomy but often do not have the benefit of seeing the…
  • 2016 American Transplant Congress

    The Live Donor Champion Program: A Novel Approach to Identying Live Kideny Donors.

    E. King, M. Bowring, K. Kumar, J. Garonzik Wang, D. Segev.

    Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD.

    Background: The Live Donor Champion (LDC) program is a clinical program offered to kidney waitlist candidates at our high volume transplant center. The six-month program…
  • 2016 American Transplant Congress

    Lower Rates of Living Donor Kidney Transplantation(LD) Among African Americans: What Prevents Higher Rates of Donation?

    A. Li, N. Foreman, M. Reissmann, C. Zuttermeister, A. Gilbert, M. Grafals, B. Javaid, S. Ghasemian, P. Abrams, M. Cooper, J. Verbesey.

    MedStar Georgetown Transplant Institute, Washington, DC.

    Purpose: African Americans (AA) are less likely to undergo LD kidney transplantation. Reasons may include decreased health literacy, increased obesity, or hypertension. We sought to…
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