2016 American Transplant Congress
C1-Inhibitor in Acute Antibody-Mediated Rejection Non-Responsive to Conventional Therapy in Kidney Transplant Recipients: A Pilot Study.
The use of complement inhibitors in the treatment of acute antibody-mediated rejection (AMR) has not been thoroughly evaluated. We performed a prospective, single-arm, pilot study…2016 American Transplant Congress
99% and 100% CPRA Patients Since KAS: A Substantial Increase in Transplants with Strong Evidence of a Bolus Effect.
1UNOS, Richmond, VA; 2Univ Hosp Case Med Ctr, Cleveland, OH; 3Emory Univ Hosp, Atlanta, GA.
Background: The Kidney Allocation System (KAS), implemented on 12/4/14, increased allocation priority for candidates with CPRA of 99-100%. Analyses performed on behalf of the OPTN…2016 American Transplant Congress
Significant Increase in Wait List Removals for Candidates Considered Too Sick from the US Kidney Transplant Waiting List.
Cleveland Clinic, Cleveland, OH.
Approximately 59,000 kidney transplant candidates have been removed from the waiting list since 2000 for reasons other than transplantation, death, or transfers. In 2014, reasons…2016 American Transplant Congress
Automated Web-Based Monitoring Identifies Significant Clinical Changes in Patients Awaiting Kidney Transplant.
Surgery, University of California-San Francisco, San Francisco, CA.
Intro: The accuracy and integrity of very large waiting lists are difficult to maintain over time. We implemented newly available information technology to increase access…2016 American Transplant Congress
Geographic Differences in Racial Disparity Reduction in Kidney Transplant Rates Before and After the New Kidney Allocation System.
1Emory University, Atlanta; 2Columbia University, New York.
Background: Prior to the new kidney allocation system (KAS) implemented 12/4/2014, significant African American (AA) vs. white racial disparities existed in access to kidney transplantation…2016 American Transplant Congress
Subtype-Compatible (A2/A2B–>B) Transplantation Under KAS Increases Access 3-Fold for Blood Type B Patients, yet Very Few Candidates Are Listed as Eligible.
Background: Prior to the new kidney allocation system (KAS; 12/4/14), 8 OPOs participated in a voluntary policy variance permitting allocation of kidneys from subtype “A2”…2016 American Transplant Congress
Wait List Removals and Transplant Rates Are Significantly Associated with Transplant Center Performance Oversight.
Cleveland Clinic, Cleveland, OH.
Prior studies indicate that low performance(LP) center evaluations by the SRTR are associated with reductions in transplant volume. There is limited information to determine whether…2016 American Transplant Congress
Impact of Cold Ischemia Time on the Outcomes of Kidneys with KDPI >85%: Mate Kidney Analysis.
Nephrology, Allegheny General Hospital, Pittsburgh, PA.
The new kidney allocation scheme recommends simultaneous local and regional offer for kidneys with KDPI >85% in order to minimize discard rates. It is unclear…2016 American Transplant Congress
Complement-Binding Donor-Specific Anti-HLA Antibodies Are Associated with Severe Kidney Allograft Arteriosclerosis.
The role of circulating donor-specific anti-HLA antibodies (DSA) in the development of accelerated arteriosclerosis have been recently reported in kidney transplant recipients. This study investigated…2016 American Transplant Congress
Molecular Significance of Microvascular Inflammation and C4d Negative Transplant Glomerulopathy.
Background: Transplant glomerulopathy (TGP) is frequently found in the setting of chronic antibody mediated rejection along with microvascular inflammation (MVI) (peritubular capillaritis+glomerulitis score > 1)…