2017 American Transplant Congress
Renal Function Variability Is a Significant and Independent Risk Factor for Graft Loss and Death in Kidney Transplantation.
1Transplant, MUSC, Charleston, SC; 2Transplant, Intermountain Healthcare, Salt Lake City, UT
Previous studies have demonstrated that the magnitude of decline in renal function can predict graft loss after kidney transplant (KTX), but there is limited research…2017 American Transplant Congress
Predictive Value of Renal Poly (ADP-Ribose) Polymerase (PARP) Expression Both in Inflammation and Interstitial Fibrosis Processes in Recipients with Antibody-Mediated Rejection.
The activation of PARP is well considered to play an augmenting role in inflammation. However, its role in the development of fibrosis is not well…2017 American Transplant Congress
Biomarkers of Epithelial-Mesenchymal Transition (EMT) in Chronic Allograft Nephropathy: Potential for Early Detection and Development of Novel Therapeutic Agents.
Pathology, BioChemistry and Medical Laboratory Sciences, Rush University Medical Center, Chicago, IL
Purpose: To detect markers and novel treatment targets related to fibrogenesis and eventual graft loss by focusing on Epithelial Mesenchymal transition (EMT) which requires understanding…2017 American Transplant Congress
Impact of Type of Kidney (Living vs. Deceased) on Urinary Podocyte Excretion Rate in Renal Allografts.
Aim: Long term allograft survival has not improved.Surveillance biopsy studies have demonstrated that chronic microcirculatory injury and progressive glomerulosclerosis are the most common histological finding…2017 American Transplant Congress
The Effect of BMI on Renal Transplant Outcomes.
1Department of Surgery, Mayo Clinic, Phoenix, AZ; 2Department of Medicine, Mayo Clinic, Phoenix, AZ
Purpose of the study was to explore the effect of BMI class on renal transplant outcomes.Method: Single center retrospective analysis of deceased and living donor…2017 American Transplant Congress
Predictors of Graft Loss in an Urban Predominantly Minority Cohort of Kidney Transplant Recipients.
Monterfiore/Einstein Center for Transplantation, Bronx, NY
BackgroundWe aimed to determine the demographic and clinical characteristics associated with graft loss in a cohort of kidney transplant recipients with a high African-American and…2017 American Transplant Congress
Urinary Type III Procollagen (PIIINP) Is Associated with Chronic Allograft Dysfunction and Predicts Graft Survival.
Background: Chronic allograft dysfunction (CAD) is the most important clinical problem in solid organ transplantation. Interstitial fibrosis and tubular atrophy contribute to long term renal…2017 American Transplant Congress
Prospective Monitoring of 25-Hydroxyvitamin Vitamin D Levels After Kidney Transplantation and Its Associations with Clinical Outcomes.
Montefiore Transplant Center, Albert Einstein College of Medicine, Bronx, NY
Background: Kidney transplant recipients usually have low vitamin D levels. Vitamin D deficiency is recognized as a risk factor for progression of kidney disease in…2017 American Transplant Congress
Changes in Urinary Neutrophil Gelatinase Associated Lipocalin Combined with Urine Cytokines and Microalbuminuria as Predictors for Interstitial Fibrosis and Tubular Atrophy in Kidney Transplantation: A Matched-Pair Tissue Cohort Study.
Background: Late graft loss from interstitial fibrosis - tubular atrophy (IF/TA) continues to be the “Achilles' heel” of kidney transplantation (KT). Long-term calcineurin inhibitors (CNIs)…2017 American Transplant Congress
Adjunctive Thymoglobulin with Proteasome Inhibitor Based Treatment of Late Mixed Acute Rejection.
1University of Cincinnati, Cincinnati; 2The Christ Hospital, Cincinnati
Proteasome inhibitor (PI) containing regimens treat mixed acute rejection (MAR) at least in part due to elimination of donor specific antibody (DSA) and via effects…
American Transplant Congress abstracts