ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Knowledge of Chronic Kidney Disease Among Liver Transplant Patients.

    J. Park, C. Koerschner, S. Selman, J. Mawby, S. Paknikar, C. Sonnenday, J. Wright Nunes, P. Sharma.

    U of Michigan, Ann Arbor

    Background: A significant proportion of liver transplant (LT) pts develop advanced chronic kidney disease (CKD) that negatively impacts mortality and morbidity. Our aim was to…
  • 2017 American Transplant Congress

    Long-Term Preservation of Renal Function in Liver Transplant Recipients with Rabbit Anti-Thymocyte Globulin Induction and Delayed Initiation of Calcineurin Inhibitors.

    I. Bajjoka, A. Yaldo, C. Crombez, K. Brown, M. Abouljoud.

    Transplant Institute, Henry Ford Health System, Detroit, MI

    Methods: A single-center retrospective analysis of medical records of 989 liver transplant recipients from 2001-2010 were reviewed and evaluated for patients who received thymo induction…
  • 2017 American Transplant Congress

    Pre-OLT CKD-3 Increases Post-OLT ESRD and AKI Impacts Early Post-OLT Survival.

    G. Faddoul, L. Liriano-Ward, P. Chang, Y. Azzi, K. Chauhan, G. Nadkarni, V. Nair, R. Kent, S. Lerner, S. Coca, P. Heeger, S. Florman, S. Thomas, M. Menon.

    Recanati Miller Transplant Institute, Icahn School of Medicine at Mount Sinai, Irvington, NY

    Current combined Liver-kidney allocation protocols allocate dual organs based on sustained glomerular filtration rates (eGFR) of 30ml/min or less. It is unclear whether milder renal…
  • 2017 American Transplant Congress

    Restrictive Approach to Simultaneous Liver Kidney Transplantation.

    S. Sultan, S. Fitzpatrick, T. Kozlowski, S. Malik, S. Hanish, D. Bruno, M. Weir, W. Hutson, R. Barth, J. LaMattina.

    Surgery, University of Maryland School of Medicine, Baltimore

    Purpose: MELD based allocation and “Share 35” policy implementation has resulted in an overall increased incidence of renal failure at the time of liver transplantation,…
  • 2017 American Transplant Congress

    Rapid Deterioration of Pre-Transplant Kidney Function Requiring Dialysis Is a Prognostic Factor in Liver Transplant Alone.

    S. Nagai,1 M. Safwan,1 K. Collins,1 M. Rizzari,1 D. Moonka,2 A. Patel,3 K. Brown,2 A. Yoshida,1 M. Abouljoud.1

    1Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI; 2Gastroenterology, Henry Ford Hospital, Detroit, MI; 3Nephrology, Henry Ford Hospital, Detroit, MI

    Aim: Etiologies of acute kidney injury before liver transplant extend beyond hepatorenal syndrome (ie infection, gastrointestinal bleeding) and therefore, may not be resolved by liver…
  • 2017 American Transplant Congress

    Evaluation of Renal Function After a Transition to Everolimus or Mycophenolate Mofetil in Liver Transplant Recipients.

    C. Perez,1 J. Fleming,1 M. Sell,1 B. O'brien,1 A. Rogers,1 I. Lee,1 C. Mardis,1 A. Mardis,1 N. Patel,1 H. Meadows,1 N. Pilch,2 K. Chavin,2 D. Dubay,2 R. Vinayak,2 D. Taber.2

    1Pharmacy, Medical University of South Carolina, Chareleston, SC; 2Surgery, Medical University of South Carolina, Charleston, SC

    Purpose: The aim of this study was to assess if there is a difference in renal function over time when transitioning to everolimus vs. mycophenolate.Methods:…
  • 2017 American Transplant Congress

    Prospective DSA Monitoring and Significance of De Novo DSA in Adult Liver Transplantation.

    S. Kubal,1 R. Mangus,1 J. Fridell,1 B. Ekser,1 R. Saxena,2 N. Rush,2 N. Higgins,4 M. Ghabril,3 M. Lacerda,3 A. Lobashevsky.4

    1Department of Surgery, Division of Transplantation, Indiana University School of Medicine, Indianapolis, IN; 2Department of Pathology, Indiana University School of Medicine, Indianapolis, IN; 3Department of Gastroenterology, Division of Hepatology, Indiana University School of Medicine, Indianapolis, IN; 4Department of Medicine, Immunology/Histocompatibility Laboratory, Indiana University School of Medicine, Indianapolis, IN

    Background: Post transplant course of circulating de novo donor specific antibodies (DSA) remains unknown after liver transplantation (LT).Methods: In a prospective study, sera from 92…
  • 2017 American Transplant Congress

    Delayed Calcineurin Inhibitor Introduction and Long Term Renal Outcomes in Liver Transplant Recipients Receiving Basiliximab Induction.

    N. Lange,1,2 D. Salerno,1 C. Sammons.2

    1Department of Pharmacy, Weill Cornell Medical Center, New York, NY; 2Department of Pharmacy, Columbia University Irving Medical Center, New York, NY

    BACKGROUND Basiliximab may be used to delay the initation of calcineurin inhibitors (CNI) in patients with renal injury after liver transplantation (LT). The optimal time…
  • 2017 American Transplant Congress

    National Variation in Liver Transplant Immunosuppression in the U.S..

    M. Nazzal,1 R. Ouseph,1 M. Schnitzler,1 Z. Zhang,1 D. Axelrod,2 D. Segev,3 A. Naik,4 H. Randall,1 D. Brennan,5 B. Kasiske,6 G. Hess,7 T. Alhamad,5 K. Lentine.1

    1St Louis Univ, St Louis; 2E Carolina Univ, Greenville; 3Johns Hopkins, Baltimore; 4U Michigan, Ann Arbor; 5Washington Univ, St Louis; 6SRTR, Minneapolis; 7Symphony Health, Philadelphia

    Variation in immunosuppression (ISx) for liver transplant (LTx) across US programs has not been described. We examined a novel database integrating national registry and pharmacy…
  • 2017 American Transplant Congress

    Subclinical Histologic Findings Are Observed in 25% of Stable Adult Liver Transplant Recipients (ALTRs) Screened for Immunosuppression Withdrawal (ISW): OPTIMAL (NCT02533180).

    S. Chandran,1 M. Abecassis,2 J. Levitsky,2 S. Feng,3 A. Humar,4 J. Emond,5 G. Klintmalm,6 A. Demetris,4 K. Much,7 L. Sun,1 A. Priore,8 D. Ikle,7 N. Bridges,8 M. DesMarais,1 B. Burrell,9 J. Markmann.10

    1ITN, San Francisco; 2Northwestern, Chicago; 3UCSF, San Francisco; 4UPMC, Pittsburgh; 5Columbia, New York; 6Baylor, Dallas; 7Rho, Chapel Hill; 8NIAID/NIH, Bethesda; 9ITN, Bethesda; 10MGH, Boston

    OPTIMAL is a 6-center ISW study in non-autoimmune, non-HCV ALTRs ≥3 yrs post-transplant (tx). Studies have shown a correlation between portal inflammation associated with tissue…
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