2017 American Transplant Congress
Knowledge of Chronic Kidney Disease Among Liver Transplant Patients.
Background: A significant proportion of liver transplant (LT) pts develop advanced chronic kidney disease (CKD) that negatively impacts mortality and morbidity. Our aim was to…2017 American Transplant Congress
Long-Term Preservation of Renal Function in Liver Transplant Recipients with Rabbit Anti-Thymocyte Globulin Induction and Delayed Initiation of Calcineurin Inhibitors.
Transplant Institute, Henry Ford Health System, Detroit, MI
Methods: A single-center retrospective analysis of medical records of 989 liver transplant recipients from 2001-2010 were reviewed and evaluated for patients who received thymo induction…2017 American Transplant Congress
Pre-OLT CKD-3 Increases Post-OLT ESRD and AKI Impacts Early Post-OLT Survival.
Recanati Miller Transplant Institute, Icahn School of Medicine at Mount Sinai, Irvington, NY
Current combined Liver-kidney allocation protocols allocate dual organs based on sustained glomerular filtration rates (eGFR) of 30ml/min or less. It is unclear whether milder renal…2017 American Transplant Congress
Restrictive Approach to Simultaneous Liver Kidney Transplantation.
Surgery, University of Maryland School of Medicine, Baltimore
Purpose: MELD based allocation and “Share 35” policy implementation has resulted in an overall increased incidence of renal failure at the time of liver transplantation,…2017 American Transplant Congress
Rapid Deterioration of Pre-Transplant Kidney Function Requiring Dialysis Is a Prognostic Factor in Liver Transplant Alone.
Aim: Etiologies of acute kidney injury before liver transplant extend beyond hepatorenal syndrome (ie infection, gastrointestinal bleeding) and therefore, may not be resolved by liver…2017 American Transplant Congress
Evaluation of Renal Function After a Transition to Everolimus or Mycophenolate Mofetil in Liver Transplant Recipients.
Purpose: The aim of this study was to assess if there is a difference in renal function over time when transitioning to everolimus vs. mycophenolate.Methods:…2017 American Transplant Congress
Prospective DSA Monitoring and Significance of De Novo DSA in Adult Liver Transplantation.
Background: Post transplant course of circulating de novo donor specific antibodies (DSA) remains unknown after liver transplantation (LT).Methods: In a prospective study, sera from 92…2017 American Transplant Congress
Delayed Calcineurin Inhibitor Introduction and Long Term Renal Outcomes in Liver Transplant Recipients Receiving Basiliximab Induction.
BACKGROUND Basiliximab may be used to delay the initation of calcineurin inhibitors (CNI) in patients with renal injury after liver transplantation (LT). The optimal time…2017 American Transplant Congress
National Variation in Liver Transplant Immunosuppression in the U.S..
Variation in immunosuppression (ISx) for liver transplant (LTx) across US programs has not been described. We examined a novel database integrating national registry and pharmacy…2017 American Transplant Congress
Subclinical Histologic Findings Are Observed in 25% of Stable Adult Liver Transplant Recipients (ALTRs) Screened for Immunosuppression Withdrawal (ISW): OPTIMAL (NCT02533180).
OPTIMAL is a 6-center ISW study in non-autoimmune, non-HCV ALTRs ≥3 yrs post-transplant (tx). Studies have shown a correlation between portal inflammation associated with tissue…