ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Utility of Porcine Kidneys in Transplantation Model for Training General Surgery Residents

    O. Eletta, V. Putatunda, D. Walls, C. Antwi-Buosiako, B. Perry, N. Maloney Patel, R. Pelletier, A. Bongu

    Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ

    *Purpose: We sought to increase the opportunities for general surgery residents to hone their vascular anastomosis skills. Accordingly, we created a kidney transplant model using…
  • 2022 American Transplant Congress

    Long-Term Implication of Kidney Injury Prior to Liver Transplantation for Acute Liver Failure

    M. R. Cloonan1, D. J. Cloonan2, S. Westphal3, L. A. Dageforde1, S. Merani1

    1Division of Transplant, Department of Surgery, University of Nebraska Medical Center, Omaha, NE, 2Division of Transplant Surgery, Massachusetts General Hospital, Boston, MA, 3University of Nebraska Medical Center, Omaha, NE

    *Purpose: Acute liver failure (ALF) is a heterogeneous disease process that often includes acute kidney injury. Long-term sequelae of kidney impairment in patients with ALF…
  • 2022 American Transplant Congress

    Four Separate Frailty Metrics Lack Concordance and Are Non-Reflective of the Kidney Transplant Listing Outcome: A Large Single Center Review

    A. Cimeno, G. Lewis, R. Parsons

    Transplant Surgery, Emory University Hospital, Atlanta, GA

    *Purpose: It is well known that functional status has prognostic value for post-surgical outcomes, however pre-transplant patients are not required to undergo objective frailty testing.…
  • 2022 American Transplant Congress

    Low T Cell Responsiveness in the Early Phase Of COVID-19 Associates with Progression to Severe Pneumonia in Kidney Transplant Recipients

    M. Cremoni1, S. Cuozzo1, E. Martinuzzi2, S. Barbosa2, N. Ben Hassen1, F. Massa3, E. Demonchy4, M. Durand5, O. Thaunat6, V. Esnault1, M. Lequintrec7, S. Caillard8, N. Glaichenhaus2, A. Sicard1

    1Service de Néphrologie, Dialyse, Transplantation rénale, Centre Hospitalier Universitaire de Nice, Nice, France, 2CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France, 3Université Côte d'Azur, Laboratoire de Physio-Médecine Moléculaire, Nice, France, 4Service d'Infectiologie, Centre Hospitalier Universitaire de Nice, Nice, France, 5Service d'Urologie, Centre Hospitalier Universitaire de Nice, Nice, France, 6Service de Transplantation rénale, Néphrologie et Immunologie clinique, Hôpital Edouard Herriot, Hospices civils de Lyon, Lyon, France, 7Service de Néphrologie, Dialyse, Transplantation rénale, Centre Hospitalier Universitaire Lapeyronie, Montpellier, France, 8Service de Néphrologie et Transplantation, Centre Hospitalier Universitaire de Strasbourg, Strasbourg, France

    *Purpose: Kidney transplant (KT) recipients are more prone to developing life-threatening forms of COVID-19 than the general population. Little is known about the immunological mechanisms…
  • 2022 American Transplant Congress

    Achievement of Persistent Mixed Chimerism in Recipients of Matched and Mismatched Living Donor Kidney Transplants in a Tolerance Induction Protocol

    J. D. Scandling, S. Busque, R. Lowsky, T. Pham, R. Hoppe, K. Jensen, A. Shori, H. Wu, R. Pawar, E. Engleman, E. Meyer, S. Strober

    Stanford University School of Medicine, Stanford, CA

    *Purpose: The induction of tolerance to kidney transplants after development of specific unresponsiveness of recipient immune cells to donor alloantigens allows elimination of maintenance immunosuppressive…
  • 2022 American Transplant Congress

    Recipient Race Modifies the Association Between Obesity and Long Term Graft Outcomes After Renal Transplantation

    F. Jarrar1, K. Tennankore2, A. J. Vinson3

    1Dalhousie University, Halifax, NS, Canada, 2Nova Scotia Health Authority, Halifax, NS, Canada, 3Nova Scotia Health Authority Division of Nephrology, Departm, Halifax, NS, Canada

    *Purpose: Both donor and recipient obesity are associated with adverse outcomes after transplant. Whether obesity, defined using body mass index (BMI), has different implications on…
  • 2022 American Transplant Congress

    Pegloticase Use in Renal Transplant Recipients with Gout: Findings from an Insurance Claims Database Study

    C. A. Shadur1, B. Marder2, C. Vesel2, B. LaMoreaux2

    1Iowa Kidney Physicians, Des Moines, IA, 2Horizon Therapeutics plc, Deerfield, IL

    *Purpose: Kidney transplant (KT) recipients have high gout incidence due to reduced eGFR and medication use associated with hyperuricemia.1 Oral urate-lowering therapies in KT patients…
  • 2022 American Transplant Congress

    Novel Immune Checkpoint Molecule TIGIT Mediates Experimental Kidney Ischemia Reperfusion Injury

    S. Noel, K. Lee, S. Gharaie, J. T. Kurzhagen, H. Rabb

    Medicine, Johns Hopkins University, Baltimore, MD

    *Purpose: T cells play both pathogenic and reparative roles in kidney ischemia reperfusion injury (IRI) but the molecular mechanisms regulating kidney T cell functions are…
  • 2022 American Transplant Congress

    Adjustment for Race and Ethnicity Does Not Change Transplant Center Outcome Metrics for Liver Recipients

    K. Ross-Driscoll1, J. Gunasti1, J. Harding1, D. Goldberg2, R. Lynch1, R. Patzer1

    1Emory University, Atlanta, GA, 2University of Miami, Miami, FL

    *Purpose: Concerns have been raised about whether transplant center metrics should be adjusted for race and ethnicity given long-standing disparities in outcomes. Proponents of adjustment…
  • 2022 American Transplant Congress

    PTLD Suspected by Visualization of Atypical Urinary Lymphocytes

    J. Huidobro E1, F. Anghileri2, P. Troncoso3, A. Huete4, P. Downey1

    1Nephrology, Pontificia Universidad Catolica de Chile, Santiago, Chile, 2Clinical Laboratories, Pontificia Universidad Catolica de Chile, Santiago, Chile, 3Urology, Pontificia Universidad Catolica de Chile, Santiago, Chile, 4Radiology, Pontificia Universidad Catolica de Chile, Santiago, Chile

    *Purpose: Urinalysis has been used for the detection of acute rejection but visualization of atypical lymphocytes in the urine sediment as an early sign of…
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