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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Racial Disparities in Preemptive Kidney Transplantation Beyond Listing Estimated Glomerular Filtration Rate

    K. L. King1, S. Husain2, S. Mohan2

    1Medicine - Nephrology, Columbia University Medical Center, New York, NY, 2Columbia University Medical Center, New York, NY

    *Purpose: Given recent attention on the impact of the race coefficient in equations for estimated glomerular filtration rate (eGFR) on racial disparities in kidney transplantation,…
  • 2022 American Transplant Congress

    Recipient Race Modifies the Association Between Obesity and Long Term Graft Outcomes After Renal Transplantation

    F. Jarrar1, K. Tennankore2, A. J. Vinson3

    1Dalhousie University, Halifax, NS, Canada, 2Nova Scotia Health Authority, Halifax, NS, Canada, 3Nova Scotia Health Authority Division of Nephrology, Departm, Halifax, NS, Canada

    *Purpose: Both donor and recipient obesity are associated with adverse outcomes after transplant. Whether obesity, defined using body mass index (BMI), has different implications on…
  • 2022 American Transplant Congress

    Trajectory Analysis Of Single Cell RNAseq Data Suggest Intrarenal Induction Of Tregs In Spontaneously Accepted Kidney Allografts

    M. Guinn1, E. S. Szuter1, T. Yokose1, J. Ge2, B. Kwon1, I. Rosales3, P. S. Russell1, A. Cuenca2, J. Madsen1, R. Colvin3, A. Alessandrini1

    1Department of Surgery, Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, 2Department of Surgery, Boston Children's Hospital, Boston, MA, 3Department of Pathology, Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA

    *Purpose: Kidney allografts transplanted across certain mouse strain combinations (e.g. DBA/2 to B6) are spontaneously accepted independent of the recipient’s thymus, spleen, and lymph nodes.…
  • 2022 American Transplant Congress

    Four Separate Frailty Metrics Lack Concordance and Are Non-Reflective of the Kidney Transplant Listing Outcome: A Large Single Center Review

    A. Cimeno, G. Lewis, R. Parsons

    Transplant Surgery, Emory University Hospital, Atlanta, GA

    *Purpose: It is well known that functional status has prognostic value for post-surgical outcomes, however pre-transplant patients are not required to undergo objective frailty testing.…
  • 2022 American Transplant Congress

    The Association of Pre-Transplant Dialysis Time and the Survival Benefit of Deceased Donor Kidney Transplantation

    W. F. Parker1, Y. Becker2, R. Gibbons1

    1University of Chicago, Chicago, IL, 2University of Chicago, Hinsdale, IL

    *Purpose: The US Kidney Allocation System (KAS) allows for deceased donor kidney transplant (DDKT) candidates not yet on dialysis to accrue waiting time points by…
  • 2022 American Transplant Congress

    Longitudinal Characterization of Memory B Cells During Antibody Mediated Rejection Treated with Plasmapheresis, Bortezomib, and Belatacept in Heart Transplant Recipients

    F. Alkhunaizi1, M. Ellison2, V. Berrich1, M. Siegelin1, M. Szabolcs1, G. F. Sayer1, N. Uriel1, S. Restaino1, A. Chong3, A. Zeevi2, M. Habal1

    1Columbia University Medical Center, New York, NY, 2University of Pittsburgh Medical Center, Pittsburgh, PA, 3University of Chicago, Chicago, IL

    *Purpose: Donor specific antibodies (DSA) and antibody mediated rejection (AMR) continue to limit allograft longevity after heart transplant. Effective treatments are limited and often complicated…
  • 2022 American Transplant Congress

    Long-Term Implication of Kidney Injury Prior to Liver Transplantation for Acute Liver Failure

    M. R. Cloonan1, D. J. Cloonan2, S. Westphal3, L. A. Dageforde1, S. Merani1

    1Division of Transplant, Department of Surgery, University of Nebraska Medical Center, Omaha, NE, 2Division of Transplant Surgery, Massachusetts General Hospital, Boston, MA, 3University of Nebraska Medical Center, Omaha, NE

    *Purpose: Acute liver failure (ALF) is a heterogeneous disease process that often includes acute kidney injury. Long-term sequelae of kidney impairment in patients with ALF…
  • 2022 American Transplant Congress

    Utility of Porcine Kidneys in Transplantation Model for Training General Surgery Residents

    O. Eletta, V. Putatunda, D. Walls, C. Antwi-Buosiako, B. Perry, N. Maloney Patel, R. Pelletier, A. Bongu

    Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ

    *Purpose: We sought to increase the opportunities for general surgery residents to hone their vascular anastomosis skills. Accordingly, we created a kidney transplant model using…
  • 2022 American Transplant Congress

    Deceased Donor Organ Flush with Similar Volumes of HTK and UW at a Single U.S. Organ Procurement Organization: Adult and Pediatric Data

    A. E. Mangus1, C. Kubal2, B. Ekser3, P. Mihaylov4, A. J. Lutz1, J. Fridell5, R. Mangus6

    1Indiana University Purdue University of Indianapolis, Indianapolis, IN, 2Indiana University Hospital, Indianapolis, IN, 3Surgery, Indiana University - Transplant Surgery, Indianapolis, IN, 4Indiana Univ School of Medicine, Indianapolis, IN, 5Indiana University School of Medicine, Indianapolis, IN, 6Indiana University, Indianapolis, IN

    *Purpose: Histidine-tryptophan-ketoglutarate (HTK) and University of Wisconsin (UW) solutions are the two primary solid-organ preservation solutions used in the United States (>95%), but flush volumes…
  • 2022 American Transplant Congress

    Long-Term Kidney Allotransplant Acceptance is Defined by a Shift from a T Cell to a B Cell Rich Immune Microenvironment Within the Graft

    E. S. Szuter1, T. Yokose1, M. T. Guinn1, J. Ge2, I. Rosales3, B. Kwon4, P. S. Russell1, A. Cuenca2, D. Kreisel5, P. Sage6, J. C. Madsen1, R. B. Colvin3, A. Alessandrini1

    1Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, 2Department of Surgery, Boston Children's Hospital, Boston, MA, 3Department of Pathology, Massachusetts General Hospital, Boston, MA, 4Harvard College, Cambridge, MA, 5Department of Surgery, Washington University, St. Louis, MO, 6Transplantation Research Center, Renal Division, Brigham and Women’s Hospital, Boston, MA

    *Purpose: Mouse kidney allografts are spontaneously accepted in select, fully-mismatched donor-recipient strain combinations, such as DBA/2J to C57BL/6 (B6). Tolerant renal grafts develop aggregates of…
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