ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2022 American Transplant Congress
    • 2021 American Transplant Congress
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2021 Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Search

Outcomes of Deceased Donor Kidney Transplantation in Elderly Recipients Aged 70 Years and Older.

A. Adamusiak,1 T. Salter,2 P. Andrews,2 C. Callaghan.1

1Department of Nephrology and Transplantation, Guy's Hospital, London, United Kingdom
2Department of Nephrology, St Helier Hospital, London, United Kingdom

Meeting: 2017 American Transplant Congress

Abstract number: A109

Keywords: Allocation, Donation, Graft survival, Kidney transplantation

Session Information

Session Name: Poster Session A: Deceased Donor Issues I: Allocation, KDPI and Recipient Selection

Session Type: Poster Session

Date: Saturday, April 29, 2017

Session Time: 5:30pm-7:30pm

 Presentation Time: 5:30pm-7:30pm

Location: Hall D1

Introduction: The number of patients aged 70 years and older receiving renal replacement therapy is increasing. There is uncertainty regarding whether listing for deceased donor kidney-only transplantation (DDKTx) is appropriate in this age group, and if outcomes post-transplant are acceptable.

Methods: UK transplant registry data from 2005 – 2013 were analysed, with end of follow-up till 2016. Outcomes of patients aged 70 and more at listing for DDKTx were compared with those aged 60-69 at listing. Post-transplant outcomes were compared in those aged ≥70 years at time of transplantation with those aged 60-69 years. Kaplan Meier method was used to compare survival between groups and hazard ratios of covariates in Cox regression survival analysis were calculated.

Results: During the study period 4739 patients aged ≥60 years were listed for DDKTx; 20.3% (960) were ≥70 years old. By 2016, 42.1% of the older cohort had been transplanted but 50.3% had been removed or died on the list. Over the same period, 3261 patients aged ≥60 years underwent DDKTx; 727 of them (22%) were aged ≥70 years. Elderly recipients were more likely to receive a kidney from an older donor (median (IQR) age 62 (53-69) vs 58 (49-66) years; p<0.001), a dual transplant (7.2% vs 4.1%; p<0.001) and a kidney with higher KDRI (1.46±0.4 vs. 1.38±0.4; p<0.001). There were no statistically significant differences in proportions of DCD donors, graft CIT, recipient ethnicity, or cRF between the two groups. Graft outcomes were similar, with no significant differences in rates of PNF (2.9% vs 3%), rejection within 3 months (9.1% vs 7.9%), or death-censored graft survival up to 10 years. eGFR of functioning grafts 1, 3, and 5 years after transplant was not statistically significant different between groups. Patient survival was worse in the elderly group (p<0.001) and more had died with a functioning graft by the end of follow-up (20.6% vs 15.2%; p<0.01).

Discussion: More than half of elderly patients listed for DDKTx are removed or die on the list. Elderly recipients have similar graft function and death-censored graft survival post-transplant to those aged 60-69 years at transplantation. Patient survival is worse, however, and a high proportion die with a functioning graft. National organ allocation scheme should be altered to enable better matching of graft survival and recipient life expectancy.

CITATION INFORMATION: Adamusiak A, Salter T, Andrews P, Callaghan C. Outcomes of Deceased Donor Kidney Transplantation in Elderly Recipients Aged 70 Years and Older. Am J Transplant. 2017;17 (suppl 3).

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Adamusiak A, Salter T, Andrews P, Callaghan C. Outcomes of Deceased Donor Kidney Transplantation in Elderly Recipients Aged 70 Years and Older. [abstract]. Am J Transplant. 2017; 17 (suppl 3). https://atcmeetingabstracts.com/abstract/outcomes-of-deceased-donor-kidney-transplantation-in-elderly-recipients-aged-70-years-and-older/. Accessed May 9, 2025.

« Back to 2017 American Transplant Congress

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2025 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use | Cookie Preferences