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Non-adherence With Diet And Dialysis Prescription: Predictors Of Non-adherence Post-transplant?

A. Padiyar1, A. Agrawal1, D. Hricik1, P. Bate2, J. Rockwell2, A. Eliason2, N. Sarabu1, A. Jittirat1, K. Yadav2, E. Sanchez2, M. Debroy2, V. Humphreville2, J. Rabets2, A. Palanisamy2, K. Chavin2

1Medicine, Nephrology, University Hospitals Cleveland Medical Center, Cleveland, OH, 2Transplant Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH

Meeting: 2019 American Transplant Congress

Abstract number: 245

Keywords: Graft survival, Kidney transplantation

Session Information

Session Name: Concurrent Session: Kidney Psychosocial I: Cognitive and Behavioral Factors

Session Type: Concurrent Session

Date: Monday, June 3, 2019

Session Time: 2:30pm-4:00pm

 Presentation Time: 3:42pm-3:54pm

Location: Room 302

*Purpose: Perceived non-adherence with diet and dialysis prescription prior to transplant may be seen as a risk for non-adherence with immunosuppression post-transplant. The importance of compliance with dialysis on post- transplant outcomes has not been sufficiently tested.

*Methods: We performed a single-center retrospective analysis of parameters that may be used to assess diet and dialysis adherence [treatment time variance, potassium, phosphorus] on post-transplant one year graft and patient survival in 101 consecutive renal transplant recipients from April 2015 to October 2018 for whom pre-transplant dialysis data was available.

*Results: Average variance from monthly prescribed treatment time was 3.94 +/- 5.97 hours (notably the average dialysis treatment was 3.83 hours). Minimal variance from treatment time, as defined by less than 2 hours per month variance, was achieved by 54.5% of patients in the month prior to transplant. 78.2% maintained serum potassium levels below the target of 5.5 for three consecutive months prior to transplant. 26.7% of patients were able to maintain serum phosphorus less than 5.5 for three months prior to transplant. Of the 101 patients studied, only 11 were able to maintain all three parameters [minimal variance from treatment time, potassium less than 5.5, and phosphorus less than 5.5] for three consecutive months pre-transplant; see Table 1 for characteristics of these patients. There were no differences in one year graft and patient survival in patients who were able to maintain any or all of the parameters.

*Conclusions: Pre-transplant patients overwhelmingly do not maintain diet and dialysis adherence consistently. The utility of using potassium, phosphorus and variance from prescribed dialysis treatment time in recipient selection is unclear.

Table 1. Patient Adherence With All Three Parameters For Three Months Prior to Transplant
NOT Adherent (85) Adherent (11) P Value
Age 53.2 +/- 12.4 45.8 +/- 9.83 0.296
Gender 56 M, 34 F 9 M, 2 F 0.332
Race 59 AA 8 AA 0.627
Donor Source 76 DD, 14 LD 10 DD, 1 LD 0.999
Prior Transplant 12 1 0.024
Diabetes 37 9 0.470
Vintage (months) 69.0 +/- 47.1 71.2 +/- 54.3 0.265
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To cite this abstract in AMA style:

Padiyar A, Agrawal A, Hricik D, Bate P, Rockwell J, Eliason A, Sarabu N, Jittirat A, Yadav K, Sanchez E, Debroy M, Humphreville V, Rabets J, Palanisamy A, Chavin K. Non-adherence With Diet And Dialysis Prescription: Predictors Of Non-adherence Post-transplant? [abstract]. Am J Transplant. 2019; 19 (suppl 3). https://atcmeetingabstracts.com/abstract/non-adherence-with-diet-and-dialysis-prescription-predictors-of-non-adherence-post-transplant/. Accessed May 9, 2025.

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