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Moving from Local Allocation to National Allocation Using Gravity Model

F. Bayer1, B. Audry2, C. Antoine2, C. Jasseron2, C. Legeais2, O. Bastien2, C. Jacquelinet1

1Agence de la biomedecine and INSERM U1018, Saint-Denis la Plaine and Villejuif, France, 2Agence de la biomedecine, Saint-Denis la Plaine, France

Meeting: 2019 American Transplant Congress

Abstract number: C278

Keywords: Allocation, Ethics, Liver transplantation

Session Information

Session Name: Poster Session C: Liver: MELD, Allocation and Donor Issues (DCD/ECD)

Session Type: Poster Session

Date: Monday, June 3, 2019

Session Time: 6:00pm-7:00pm

 Presentation Time: 6:00pm-7:00pm

Location: Hall C & D

*Purpose: Most allocation scheme are based on optimized or administrative boundaries that do not allow transplant candidates without national priority to access a graft from another allocation area, even if they are physically close to it. This situation leads to inequities especially for most urgent candidates. To deal with this issue, a continuous geographical allocation model, referred to as a gravity model was introduced in 2011 in France for liver transplantation (LTx) to replace the previous concentric (local-regional-national) geographical model. We report on how such a model resulted in more equitable access to liver transplantation by introducing a spatial interaction between the distance and the medical condition of the liver transplantation candidates, summarized into a medical score.

*Methods: All patients registrered on the national waiting list for a LTx from 2007 to 2011 (before implementation of gravity model , n = 4246) and from 2011 to 2014 (after implementation of gravity model, n = 4907) were included in our study, using data from the Agence de la biomédecine database (CRISTAL). A 3-years follow up at Decembrer 31, 2017 was required. Death and dropout from the waiting list, post-transplant survival, cold ischemia and teams’ travels by LTx candidate’s medical score were compared between the two periods.

*Results: Compared to our previous LTx allocation scheme, most urgent candidates got an improved access to LTx all over the country. Very low MELD score cirrhotic patients (<15), whose registration on the waiting list was still allowed, got a very limited access to LTx, with no increase in death on the waiting list. Death and withdrawal from the waiting list dropped from 15% one year after the implementation and post-transplant survival significantly increased (fig.1). Cold Ischemia time has been reduced with no change on cumulated teams’ travel time..

*Conclusions: This disruptive alternative to arbitrary administrative boundary in organ allocation provides a compromise between distance and candidate’s urgency. This model also fixed the disparity problem encounter with geographical boundaries, allowing candidates close to a graft but not in its allocation zone to access this organ.

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To cite this abstract in AMA style:

Bayer F, Audry B, Antoine C, Jasseron C, Legeais C, Bastien O, Jacquelinet C. Moving from Local Allocation to National Allocation Using Gravity Model [abstract]. Am J Transplant. 2019; 19 (suppl 3). https://atcmeetingabstracts.com/abstract/moving-from-local-allocation-to-national-allocation-using-gravity-model/. Accessed May 18, 2025.

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