ATC Abstracts

American Transplant Congress abstracts

Live Kidney Donor Evaluation: Association of Race With Ineligibility

Johns Hopkins, Baltimore.

Meeting: 2015 American Transplant Congress

Abstract number: C170

Keywords: ,

Session Information

Date: Monday, May 4, 2015

Session Name: Poster Session C: Living Donor Issues 2

Session Time: 5:30pm-6:30pm

 Presentation Time: 5:30pm-6:30pm

Location: Exhibit Hall E

Background: African American (AA) waitlist candidates face many barriers to identifying LKDs. However, even if AA candidates identify a potential donor, it is unclear whether these donors will eventually be approved for donation or deemed ineligible.

Methods: We performed a retrospective study of 1,286 potential LKDs referred for evaluation at our center from 1/2011-3/2014. Competing risk regression was used to model chance of approval and ineligibility.

Results: Overall, 15% of potential donors were approved for donation within 18-months of referral, and 30% of potential donors were deemed ineligible.

Table 1. Baseline characteristics for donor candidates referred for live donor kidney evaluation
  Referred donors (n=1,286)
Age (IQR) 45 (35, 55)
Male, n(%) 485 (38)
AA, n(%) 292 (28)
College or more, n(%) 578 (53)
BMI, n(%)  
Underweight (less than 18.5) 7 (1)
Normal (18.5-25) 393 (36)
Overweight (25-30) 398 (36)
Obese (more than 30) 295 (27)
Relationship Type to Recipient, n(%)  
Biological 511 (46)
Non-Biological 424 (38)
Spousal 143 (13)
Other 26 (2)
After adjusting for age, sex, and BMI, AA race was significantly associated with ineligibility (1.041.401.89 p=0.03).

Table 2. Sub Hazard Ratios for Ineligibility
  Sub Hazard Ratio p-value
Age 0.991.021.02 0.2
Male Sex 0.760.991.31 0.9
AA Race 1.041.401.89 0.03
BMI>30 1.702.262.99 <0.001
BMI>30 was statistically significantly associated with an increased chance of ineligibility (1.702.262.99 p<0.001).

Conclusion: Both AA race and high BMI increase the chance of ineligibility for live kidney donation.

To cite this abstract in AMA style:

Kumar K, Poon A, Massie A, Muzaale A, Purnell T, Tonascia J, King E, Segev D. Live Kidney Donor Evaluation: Association of Race With Ineligibility [abstract]. Am J Transplant. 2015; 15 (suppl 3). https://atcmeetingabstracts.com/abstract/live-kidney-donor-evaluation-association-of-race-with-ineligibility/. Accessed January 27, 2021.

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