Live Kidney Donor Evaluation: Association of Race With Ineligibility

K. Kumar, A. Poon, A. Massie, A. Muzaale, T. Purnell, J. Tonascia, E. King, D. Segev.

Johns Hopkins, Baltimore.

Meeting: 2015 American Transplant Congress

Abstract number: C170

Keywords: Donation, Kidney transplantation

Session Information

Session Name: Poster Session C: Living Donor Issues 2

Session Type: Poster Session

Date: Monday, May 4, 2015

Session Time: 5:30pm-6:30pm

Presentation Time: 5:30pm-6:30pm

Location: Exhibit Hall E

Background: African American (AA) waitlist candidates face many barriers to identifying LKDs. However, even if AA candidates identify a potential donor, it is unclear whether these donors will eventually be approved for donation or deemed ineligible.

Methods: We performed a retrospective study of 1,286 potential LKDs referred for evaluation at our center from 1/2011-3/2014. Competing risk regression was used to model chance of approval and ineligibility.

Results: Overall, 15% of potential donors were approved for donation within 18-months of referral, and 30% of potential donors were deemed ineligible.

Table 1. Baseline characteristics for donor candidates referred for live donor kidney evaluation
	Referred donors (n=1,286)
Age (IQR)	45 (35, 55)
Male, n(%)	485 (38)
AA, n(%)	292 (28)
College or more, n(%)	578 (53)
BMI, n(%)
Underweight (less than 18.5)	7 (1)
Normal (18.5-25)	393 (36)
Overweight (25-30)	398 (36)
Obese (more than 30)	295 (27)
Relationship Type to Recipient, n(%)
Biological	511 (46)
Non-Biological	424 (38)
Spousal	143 (13)
Other	26 (2)

After adjusting for age, sex, and BMI, AA race was significantly associated with ineligibility (_1.041.40_1.89 p=0.03).

Table 2. Sub Hazard Ratios for Ineligibility
	Sub Hazard Ratio	p-value
Age	_0.991.02_1.02	0.2
Male Sex	_0.760.99_1.31	0.9
AA Race	_1.041.40_1.89	0.03
BMI>30	_1.702.26_2.99	<0.001

BMI>30 was statistically significantly associated with an increased chance of ineligibility (_1.702.26_2.99 p<0.001).

Conclusion: Both AA race and high BMI increase the chance of ineligibility for live kidney donation.

To cite this abstract in AMA style:

Kumar K, Poon A, Massie A, Muzaale A, Purnell T, Tonascia J, King E, Segev D. Live Kidney Donor Evaluation: Association of Race With Ineligibility [abstract]. Am J Transplant. 2015; 15 (suppl 3). https://atcmeetingabstracts.com/abstract/live-kidney-donor-evaluation-association-of-race-with-ineligibility/. Accessed November 21, 2024.

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