ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Advanced Search

Live Donor Liver Transplantation With Older (>50years) Vs Younger (<50years) Donors: Does Age Matter?

N. Goldaracena, G. Sapisochin, J. Echeverri, M. Kaths, N. Selzner, M. Cattral, P. Greig, L. Lilly, I. McGilvray, G. Levy, A. Ghanekar, E. Renner, D. Grant, M. Selzner.

Multi Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada.

Meeting: 2015 American Transplant Congress

Abstract number: 404

Keywords: Living-related liver donors

Session Information

Date: Tuesday, May 5, 2015

Session Name: Concurrent Session: Liver: Living Donors and Partial Grafts

Session Time: 2:15pm-3:45pm

 Presentation Time: 3:27pm-3:39pm

Location: Room 115-AB

Related Abstracts
  • Live Donor Vs Deceased Donor Liver Transplantation Results in Identical Outcome in Recipients With Acute Liver Failure – An Important Choice for Critical Ill Patients
  • Comparison of Pediatric En-Bloc Renal Allograft Growth and Function for Donors Less Than One Year of Age with Older Pediatric Donors

Introduction: The risks of living donor liver transplantation (LDLT) with older donors remains controversial and many centers avoid using live donors ≥45 years of age. We determined in a single center series the outcomes of LDLT with grafts from older vs younger donors.

Methods: From 2000-2014, 469 adult-to-adult right lobe LDLT were performed at our institution. Outcome of patients receiving a LDLT graft from donors ≥50 years (LDLT≥50 =91) were compared to patients receiving a live donor graft from donors <50 years (LDLT<50=378).

Results: No difference was observed between groups regarding recipient demographic variables and disease severity. Recipient ICU (LDLT<50: 1 vs. LDLT≥50: 2 days; p=0.28) and hospital stay (LDLT<50: 12 vs. LDLT≥50: 14 days; p=0.1) after transplantation was similar. The incidence of major complication in recipients (Clavien ≥3b) was similar between both groups (LDLT<50: 24% vs. LDLT≥50: 24%; p=1). The incidence of biliary complications were the same between both groups (LDLT<50: 24% vs. LDLT≥50: 23%; p=0.84). No difference was observed regarding 30-day recipient mortality (LDLT<50: 3% vs. LDLT≥50: 0%; p=0.13). In contrast, 1-year graft lost was lower after LDLT with younger vs older grafts (LDLT<50: 5(1%) vs. LDLT≥50: 5(5%); p=0.028). The 1- (90% vs. 90%), 5- (82% vs. 73%) and 10- (71% vs. 58%) year graft survival was similar in the LDLT<50yr vs >50yr group (p=0.075). Patient survival after 1-(92% vs. 96%), 5-(83% vs. 79%) and 10-years (76% vs. 69%) was similar between both groups (p=0.68). No donor death occurred and all donors had full recovery. Median hospital stay for both groups of donors was the same (LDLT<50: 6(4-17) vs. LDLT≥50: 6(4-14) days; p=0.65). Donor mayor postoperative complications were very low and identical between both groups (LDLT<50: 9(2%) vs. LDLT≥50: 2(2%); p=1)

Conclusion: LDLT with donors >50 years of age results in acceptable recipient outcome without increased donor morbidity. Potential living donors should not be declined based on age alone.

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Goldaracena N, Sapisochin G, Echeverri J, Kaths M, Selzner N, Cattral M, Greig P, Lilly L, McGilvray I, Levy G, Ghanekar A, Renner E, Grant D, Selzner M. Live Donor Liver Transplantation With Older (>50years) Vs Younger (<50years) Donors: Does Age Matter? [abstract]. Am J Transplant. 2015; 15 (suppl 3). https://atcmeetingabstracts.com/abstract/live-donor-liver-transplantation-with-older-50years-vs-younger-50years-donors-does-age-matter/. Accessed January 27, 2021.

« Back to 2015 American Transplant Congress

Most Viewed Abstracts

  • This Week
  • This Month
  • All Time
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Penis Transplantation: First U.S. Experience.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Live Related Kidney Transplant Experience in Abuja, Nigeria – First Eight Cases Ever.
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Penis Transplantation: First U.S. Experience.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Live Related Kidney Transplant Experience in Abuja, Nigeria – First Eight Cases Ever.

    Visit Our Partner Sites

    American Transplant Congress (ATC)

    Visit the official site for the American Transplant Congress »

    American Journal of Transplantation

    The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

    American Society of Transplantation (AST)

    An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

    American Society of Transplant Surgeons (ASTS)

    The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

    Copyright © 2013-2021 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

    Privacy Policy

    loading Cancel
    Post was not sent - check your email addresses!
    Email check failed, please try again
    Sorry, your blog cannot share posts by email.
    This site uses cookies: Find out more.