Psycho-social factors are common in patients with advanced and end stage kidney disease and they may be associated with post kidney transplant outcomes. The aim of this study was to determine the correlations between pre-transplant, nonclinical and psycho-social factors to post-transplant clinical outcomes. BODY-Methods: We selected the following pre-transplant factors: gender, food stamp, marital relationship, income status, insurer, education, transportation, Karnofsky score, history of depression, proper exercise, albumin level history of substance abuse, distance from patient home to UTMB clinic. The post-transplant clinical outcomes selected were quality of kidney allograft at 6 months expressed as serum creatinine. The study involved retrospective analysis of 136 kidney transplant patients. There were 56 female patients and 75 male patients. We had 72 Hispanics (53%), 33 African Americans (24%), 22 Whites (16%), 9 Asians (7%). We used nominal logistic regression analysis and multinominal logistic regression analysis to identify the significant relationship between one dependent nominal variable and one or more continuous-level independent variables. A p-value of ≤ 0.05 was considered significant. BODY-Results: Factors associated with significantly better serum creatinine at 6 months included: Female gender (p 0.014), active pre listing clinic follow up (0.0001), compliance with dialysis (0.06), and serum albumin >3.5 gm/dl (0.007). Patient primary insurer, family support, mariatal status, exercise, food stamp status, history of depression, history of substance abuse, education level, race, distance from transplant center, and retransplant status was not found to be associated with 6 months serum creatinine.

BODY-Conclusion: Pre-transplant psychosocial factors are associated with the post transplant kidney allograft function . This also shows the pre transplant psycho-social history is an integral but often ignored part of evaluation and should be stressed upon. More prospective trials are required to confirm our findings.

CITATION INFORMATION: Shah S., Gamilla-Crudo A., Schreiber B., Machner C., Aleter O., Mujtaba M. Inter-Correlations between Psycho-Social Pre-Transplant Determinants of Post-Transplant Kidney Allograft Function Am J Transplant. 2017;17 (suppl 3).

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