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Impact of Pretransplant Infectious Diseases Wellness Visit on Vaccine Uptake in Solid Organ Transplant Candidates

J. Jarrah, Z. Hanna, J. Williams, J. McCorquodale, T. Párraga, S. Greenlee, O. Abreu Lanfranco, M. Ramesh, R. del Busto, G. Alangaden

Transplant Infectious Diseases, Henry Ford Hospital, Detroit, MI

Meeting: 2022 American Transplant Congress

Abstract number: 1189

Keywords: Infection, Screening, Vaccination

Topic: Clinical Science » Organ Inclusive » 70 - Non-Organ Specific: Disparities to Outcome and Access to Healthcare

Session Information

Session Name: Non-Organ Specific: Disparities to Outcome and Access to Healthcare

Session Type: Poster Abstract

Date: Sunday, June 5, 2022

Session Time: 7:00pm-8:00pm

 Presentation Time: 7:00pm-8:00pm

Location: Hynes Halls C & D

*Purpose: Vaccination rates in solid organ transplant candidates (SOTc) remains suboptimal. We report the effect of a dedicated Infectious Disease Pre-transplant (IDPT) clinic visit on vaccine uptake in SOTc.

*Methods: We evaluated all SOTc referred to the IDPT from January 2020 to February 2021 at Henry Ford Transplant Institute in Detroit, MI. Patients were followed up until October 2021. Sociodemographic data, comorbidities, vaccination status for influenza, pneumococcus, hepatitis B, Tdap, zoster and COVID-19 were determined from electronic medical records and the Michigan Care Improvement Registry that includes vaccination records. Vaccine uptake at baseline and 3 and 6 months after IDPT visit were evaluated.

*Results: A total of 183 SOTc were evaluated in IDPT. Median age was 57 years, mean Charlson Comorbidity Index was 4.1. Other characteristics are summarized (Table 1). Vaccine uptake improved post IDPT for all vaccines (Table 2), most notably for hepatitis B (53.4%), zoster (40.4%) and pneumococcal vaccine (33.4%). COVID vaccine uptake post visit was 80.3%.

*Conclusions: IDPT clinic visits steadily improved vaccine uptake in SOTc at our institution. Implementation of an Infectious Diseases visit as a requirement for all SOTc can provide opportunities to optimize vaccine completion before transplantation.

Table 1. Transplant Type
Organ N (%)
Heart 46 (25.1)
Kidney 67 (36.6)
Liver 30 (16.4)
Lung 33 (18)
Multivisceral 6 (3.3)
Table 2. Characteristics of 183 SOT candidates
Variable Value
Age (year), median (IQR) 57 (49-65)
Male sex (N, %) 114 (62.3)
Race (N, %)-Black 62 (33.9)
Insurance type (N, %)-Medicare 94 (51.4)
Distance (miles) to center (mean, IQ) 52.5 (13.5-62.2)
Charlson Comorbidity Index score (Mean, SD) 4.1 (1.98)
IDPT clinic provider (N, %)-NP 167 (91.3)
Table 3. Vaccination status in 183 SOT candidates before and after ID visit
Vaccine Eligible pre-transplant, N Vaccination before IDPT visit, N (%) Vaccination after IDPT visit at 3 months, N (%) Vaccination after IDPT visit >6 months, N (%) Vaccination uptake after IDPT visit, N (%)
Influenza 183 98 (53.6) 139 (76.0) 147 (80.3) 49 (26.8)
Pneumococcal 183 77 (42.0) 121 (66.1) 138 (75.4) 61 (33.3)
Hepatitis B 103 (80/183 already HBV immune) 31 (30.1) 73 (70.9) 86 (83.5) 55 (53.4)
Tdap 183 101 (55.2) 130 (71.0) 142 (77.5) 41 (22.4)
Varicella (Shingrix) 183 36 (19.7) 101 (55.1) 110 (60.1) 74 (40.4)
COVID-19 183 NA 112 (61.2) 147 (80.3) –

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To cite this abstract in AMA style:

Jarrah J, Hanna Z, Williams J, McCorquodale J, Párraga T, Greenlee S, Lanfranco OAbreu, Ramesh M, Busto Rdel, Alangaden G. Impact of Pretransplant Infectious Diseases Wellness Visit on Vaccine Uptake in Solid Organ Transplant Candidates [abstract]. Am J Transplant. 2022; 22 (suppl 3). https://atcmeetingabstracts.com/abstract/impact-of-pretransplant-infectious-diseases-wellness-visit-on-vaccine-uptake-in-solid-organ-transplant-candidates/. Accessed May 20, 2025.

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