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Geographic Disparities in Liver Supply/Demand Ratio within Fixed-Distance and Fixed-Person Circles

C. Haugen1, T. Ishaque1, A. Sapirstein1, D. Segev1, S. Gentry2

1JHU, Baltimore, MD, 2USNA, Baltimore, MD

Meeting: 2019 American Transplant Congress

Abstract number: C280

Keywords: Allocation, Liver transplantation

Session Information

Session Name: Poster Session C: Liver: MELD, Allocation and Donor Issues (DCD/ECD)

Session Type: Poster Session

Date: Monday, June 3, 2019

Session Time: 6:00pm-7:00pm

 Presentation Time: 6:00pm-7:00pm

Location: Hall C & D

*Purpose: Geographic disparity in deceased donor liver allocation has been extensively documented. Many stakeholders believe allocating within circular fixed-distance or fixed-person boundaries would reduce geographic disparity.

*Methods: We identified 27,334 transplanted deceased donor livers and 44,652 incident waitlist candidates with MELD≥15 using SRTR data (07/2013-06/2017). We examined organ supply/demand ratios for 142 transplant centers. Supply was the number of donors from ZIP codes around a center, allocated proportionally according to waitlist size, and demand was the number of liver registrants. We measured disparity (variance) in supply/demand ratio between transplant centers for DSAs, fixed-distance circles (150- or 400-mile radius), and fixed-person (12- or 50-million) circles with the variance ratio test.

*Results: The variance in supply/demand ratio within DSAs was 0.11, which did not decrease for 150-mile radius circles (variance=0.11, p=0.9) or 12-million-person circles (variance=0.08, p=0.1). However, the variance in supply/demand ratio decreased substantially from 0.11 to 0.02 in larger fixed-distance (400-mile, p<0.001) and larger fixed-person (50-million, p<0.001) circles. Compared to fixed-distance circles, fixed-person circles with similar median radius yield similar reductions in disparity across transplant centers (400-mile vs. 50-million, p=0.9; 150-mile vs. 12-million, p=0.3).

*Conclusions: Small fixed-distance (150-mile) or fixed-person circles (12-million) do not reduce geographic disparity compared to DSAs. Fixed-distance or fixed-person circles must be larger than those in current allocation policy to reduce geographic disparities.

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To cite this abstract in AMA style:

Haugen C, Ishaque T, Sapirstein A, Segev D, Gentry S. Geographic Disparities in Liver Supply/Demand Ratio within Fixed-Distance and Fixed-Person Circles [abstract]. Am J Transplant. 2019; 19 (suppl 3). https://atcmeetingabstracts.com/abstract/geographic-disparities-in-liver-supply-demand-ratio-within-fixed-distance-and-fixed-person-circles/. Accessed May 9, 2025.

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