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Five Years after Right Hepatectomy for Living Liver Donation: Donor State of Health

D. P. Hoyer, E. Malamutmann, G. Bagias, A. Oezcelik

General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany

Meeting: 2019 American Transplant Congress

Abstract number: B330

Keywords: Liver transplantation, Living-related liver donors

Session Information

Session Name: Poster Session B: Liver: Living Donors and Partial Grafts

Session Type: Poster Session

Date: Sunday, June 2, 2019

Session Time: 6:00pm-7:00pm

 Presentation Time: 6:00pm-7:00pm

Location: Hall C & D

*Purpose: Of utmost importance in living liver donation is the avoidance of postoperative complications and reduction of quality of life of the donor.

*Methods: Inclusion criteria for this study were liver donors between 01/2005 and 12/2013 with a completed follow-up of at least 5 years and personal availability. Retrospectively, preoperative, intraoperative and postoperative donor data were investigated. Additionally, all donors received a survey regarding their quality of life. Statistical analysis was performed with Graph Pad Prism (GraphPad Sofware, Inc. Version 8.0.0).

*Results: We included 192 living liver donors (median age 31 years) in this study. Donor characteristics are displayed in table 1. Postoperative complications were observed in 32 (16.6.%) patients, two of these were classified as severe complications (>3b Dindo-Clavien) and subsequently treated by surgical intervention.

Results of the questionnaire demonstrated excellent status of health in 91.7% of donors. General physical performance was excellent or good in 85.5% and 99.5% of donors reported to live daily life as not having been treated surgically before.

None of the donors reported disadvantages in their work life due to the donation. More than two thirds (70.2%) of donors would definitely decide to donate again, this included the two patient with severe complications (table 2). No difference was observed between donors with and without complications.

*Conclusions: Living liver donors have excellent quality of life in the long term. Satisfaction with the surgical interventions is high as well.

Donor Data
Gender (m/f) 99/93
BMI 24.5 (IQR 22.4-27.0)
Ratio Remnant to total Liver volume 35% (IQR 32%-37%)
Duration of Surgery (minutes) 260 (IQR 205-315)
Bilirubin on POD 7 (mg/dl) 1.0 (IQR 0.7-1.9)
INR on POD 7 1.2 (IQR 1.1-1.3)
Results of the questionnaire
Questions Answers
What is your state of health excellent: 28.9% good: 62.8% moderate: 17.3% bad: 1.0% very bad: 0%
How is your general physical condition excellent: 16.1% good: 69.4% moderate: 12.5% bad: 1.5% very bad: 0.5%
Did you have psychological problems after donation yes, lots: 3.0% yes, some: 24.6% no: 72.4%
When did life return to normality <3months: 47.9% 3-6months: 27.2% 6-12months: 18.7% >12months: 5.7% Never: 0.5%
Did you have professional disadvantages due to donation yes: 0% no: 100%
Would you decide for donation again  today yes: 70.2% I don’t know: 24.4% no: 5.4%

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To cite this abstract in AMA style:

Hoyer DP, Malamutmann E, Bagias G, Oezcelik A. Five Years after Right Hepatectomy for Living Liver Donation: Donor State of Health [abstract]. Am J Transplant. 2019; 19 (suppl 3). https://atcmeetingabstracts.com/abstract/five-years-after-right-hepatectomy-for-living-liver-donation-donor-state-of-health/. Accessed May 11, 2025.

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