ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Advanced Search

Fate of 535 Renal Allografts Retrieved from Donors after Cardiac Death and Risk Factors Affecting Long-Term Graft Survival (Single Center Experience during Three Decades), The

M. Kusaka, Y. Kubota, M. Takenaka, N. Fukami, H. Sasaki, R. Shiroki, T. Kenmochi, K. Hoshinaga

Department of Urology, Fujita-Health University, Toyoake, Aichi, Japan
Department of Organ Transplant Surgery, Fujita-Health University, Toyoake, Aichi, Japan

Meeting: 2013 American Transplant Congress

Abstract number: 536

Related Abstracts
  • Long-Term Graft Survival Retrieved from Donors after Cardiac Death Have Been Significantly Improved in These Two Decades Although the Procurement Technique Remains Unchanged during the Three Decades
  • Matching of Recipient and Donor Age Is the Most Powerful Risk Factor Affecting to Long-Term Graft Survival and Function

Introduction: The kidneys procured from deceased donors in donation after cardiac death (DCD) hold great potential to expand the donor pool but have not yet been fully utilized, in part because of concerns about graft dysfunction. In this study, the posttransplant outcome of renal allografts recovered from DCD donors is investigated and the risk factors affecting the renal prognoses were analyzed. Methods: From 1979 to the end of Nov. 2012, 535 kidneys were retrieved from 270 DCD donors at our center, using in situ regional cooling technique. Only 49 (9.2%) grafts had discarded and 443 grafts transplanted since 1983 through 2011 were enrolled in this study. The age of the donors and recipients ranged from 0.7 to 75 (mean; 47.6) and from 7 to 72 (mean; 41.7). The warm ischemic time ranged from 1 to 71 minutes (mean; 11.7). The serum creatinine level before cardiac arrest ranged from 0.4 to 5.4 mg/dl (mean; 1.49). All the patients were treated with immunotherapy consiting of calcineurin inhibitos, steroid and other immunosuppressants. For the statistical analysis, Kaplan-Meier method and Log-rank test were used. Results: Following renal transplants, primary non function (PNF) was noted in 27 (6.5%), immediate function (IF) was 58 (13.1%), and DGF was 358 (80.9%). The 1, 3, 5, and 10 year patient survival rates were 97.0%, 92.1%, 90.0%, and 82.9%, respectively. The 1, 3, 5, and 10 year graft survival rates were 86.1%, 75.6%, 68.5%, and 52.8%, respectively.

The significant risk factors for graft failure were donor age, cause of death (CVA), donor hypertension and WIT. Conclusion: Renal grafts recovered from DCDs had good renal function as well as excellent long term graft survival, when in situ regional cooling technique was applied. DCD donors should be the excellent resources of deceased donor kidneys, and they can increase the number of renal transplantation in the era of sever organ shortage.

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Kusaka M, Kubota Y, Takenaka M, Fukami N, Sasaki H, Shiroki R, Kenmochi T, Hoshinaga K. Fate of 535 Renal Allografts Retrieved from Donors after Cardiac Death and Risk Factors Affecting Long-Term Graft Survival (Single Center Experience during Three Decades), The [abstract]. Am J Transplant. 2013; 13 (suppl 5). https://atcmeetingabstracts.com/abstract/fate-of-535-renal-allografts-retrieved-from-donors-after-cardiac-death-and-risk-factors-affecting-long-term-graft-survival-single-center-experience-during-three-decades-the/. Accessed January 18, 2021.

« Back to 2013 American Transplant Congress

Most Viewed Abstracts

  • This Week
  • This Month
  • All Time
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Penis Transplantation: First U.S. Experience.
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Live Related Kidney Transplant Experience in Abuja, Nigeria – First Eight Cases Ever.
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Penis Transplantation: First U.S. Experience.
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Kidney Dialysis after Heart Transplantation: The Short and Long Term Outcomes
  • Penis Transplantation: First U.S. Experience.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Evidence of a Clinically Significant Drug-Drug Interaction between Cannabidiol and Tacrolimus: A Case Report
  • Kidney Dialysis after Heart Transplantation: The Short and Long Term Outcomes

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2021 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy

loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.