*Purpose: The Stanford Integrated Psychosocial Assessment for Transplant (SIPAT) is a psychometric instrument designed to improve organ transplant patient selection. However, limited studies have been conducted on its efficacy in determining transplant outcomes. We investigated the association between SIPAT scores and demographic data with psychosocial and medical outcomes within a diverse kidney/kidney-pancreas transplant population.

*Methods: We prospectively administered the SIPAT to all pre-transplant candidates and completed a retrospective review of transplanted patients who had at least 6 months of follow-up. A total of 136 patients were identified [male, n=77 (57%)] with a mean age of 47 years-old. 38% were Black (n=51), 55% had ≤HS education (n=74), and 65% had low socioeconomic status (n=89).

*Results: Statistical difference was found among SIPAT scores and substance use and support system instability (P=0.035, P=0.012), while demographic factors were more associated with medical outcomes. Females (P=0.012) and patients with history of psychopathology (P=0.002) experienced psychopathology following transplant more often. Patients with more than a HS education (P=0.025) and were <30 years (P=0.026) had higher rejection incidence rates. Risk factors for re-hospitalizations included Hispanic race, diabetes, and low SES (P=0.036, P=0.038, P=0.014). Black and male patients had higher incidence of infection events (P=0.032, P=0.049). Mortality and treatment non-adherence were not significantly associated with SIPAT scores or demographic variables.

*Conclusions: The SIPAT was associated with post-transplant substance use and support system instability, while demographic variables were associated with other transplant outcomes. Revision of the SIPAT to include additional demographic components may lend to better prediction of transplant outcomes.

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