*Purpose: Although liver transplant (LT) recipients are at high cardiovascular risk, the management of cardiovascular risk factors (CVRF) after LT is far from optimal. We designed a multi-professional, multidisciplinary protocol to improve our grade of awareness and control of CVRF after LT.

*Methods: A multidisciplinary protocol was developed in 2017 to standardize the risk stratification, CVRF management and targets of therapy during the first post-LT year. The post-intervention cohort consisted in patients who underwent LT between January 2018 and January 2020 (n=150). The grade of awareness and control of CVRF 12 months after LT were compared to those of patients who underwent LT between July 2015 and December 2016 (control cohort, n=100).

*Results: Before LT, the prevalence of MAFLD as the indication of LT and the presence of obesity were significantly higher in the post-intervention cohort, while the prevalence of other CVRF and renal dysfunction tended to be higher. Twelve months after LT, the proportion of patients with measured blood pressure (88% vs 56%), HbA1c (96% vs 72%) and HDL/LDL-cholesterol (67% vs 33%) was higher in the post-intervention than in the control cohort (all p<0.001). In addition, blood pressure and HbA1c were at target levels in more individuals with hypertension (64% vs. 36%, p=0.02) and diabetes (85% vs. 70%, p=0.1) in the post-intervention than in the control cohort. Total cholesterol levels in patients with dyslipidemia were lower in the post-intervention (184 [160-210]) mg/dl than in the control cohort (212 [186-240]), p=0.02.

*Conclusions: A multidisciplinary, multi-professional strategy can achieve higher awareness and better control of post-LT CVRF despite a worse metabolic profile of LT recipients and may result in improved long-term outcomes.

« Back to 2022 American Transplant Congress