Effect of Ethnicity on Recipient Characteristics, Kidney Transplant Provision and Outcomes in a High-Volume National Health Service Hospital
1Kidney Transplant, Fondazione IRCCS Ca&apos
Granda, Ospedale Maggiore Policlinico, Milan, Italy
2Kidney Transplant, Barts Health NHS Trust, The Royal London Hospital, London, United Kingdom.
Meeting: 2018 American Transplant Congress
Abstract number: A325
Keywords: Graft survival, Kidney transplantation, Outcome, Survival
Session Information
Session Name: Poster Session A: Non-Organ Specific: Disparities to Outcome and Access to Healthcare
Session Type: Poster Session
Date: Saturday, June 2, 2018
Session Time: 5:30pm-7:30pm
Presentation Time: 5:30pm-7:30pm
Location: Hall 4EF
Background. Several reports have demonstrated that outcomes of kidney transplantation (KTx) can be influenced by recipient's ethnicity and social status. However, available data mostly refer to Caucasian, Afro-Caribbean or Hispanic patients treated in a private or insurance-based health care setting. Methods. In this single-centre retrospective study performed in an urban public health service hospital (NHS-England), we analyzed baseline characteristics and outcomes of 551 consecutive KTx in recipients belonging to 3 main ethnic groups: CAU (284 Caucasian patients), AFR (116 Afro-Caribbean patients), and PEN (151 Indian-Pakistani-Bangladeshi patients). Results. Main results after 5 years of follow up are summarized in the table.
| CAU (n=284) | AFR (n=116) | PEN (n=151) | P | |
| Glomerular disease (%) | 31 | 15 | 20 | <0.05 |
| Polycystic kidney disease (%) | 16 | 7 | 3 | <0.05 |
| Nephroangiosclerosis (%) | 6 | 19 | 5 | <0.05 |
| Unknown primary disease (%) | 14 | 31 | 32 | <0.05 |
| Pre-KTx hypertension (%) | 35 | 60 | 55 | <0.05 |
| Pre-KTx diabetes (%) | 15 | 20 | 35 | <0.05 |
| Pre-Tx cardiovascular disease (%) | 10 | 20 | 25 | <0.05 |
| Smoking habit (%) | 20 | 40 | 35 | <0.05 |
| Preemptive KTx (%) | 16 | 6 | 7 | <0.05 |
| Living-donor KTx (%) | 45 | 34 | 26 | <0.05 |
| Patient survival (%) | 91 | 90 | 85 | <0.05 |
| Graft survival (%) | 83 | 74 | 75 | <0.05 |
| Delayed graft function (%) | 23 | 34 | 25 | <0.05 |
| Rejection (%) | 31 | 28 | 15 | <0.05 |
| Post-KTx hypertension (%) | 35 | 58 | 65 | <0.05 |
| Post-KTx diabetes (%) | 6 | 14 | 18 | <0.05 |
| Polyomavirus (%) | 8 | 16 | 7 | <0.05 |
Conclusions. Our data show that minorities have inferior KTx outcomes even in a public health service. Higher comorbidity at the time of enlistement, suboptimal access to preemptive and living donor transplant programs, and cultural barriers might explain these findings. Further investigation is warranted to confirm this hypothesis and test possible implementation strategies.
CITATION INFORMATION: Favi E., Puliatti C., Ferraresso M., Cacciola R. Effect of Ethnicity on Recipient Characteristics, Kidney Transplant Provision and Outcomes in a High-Volume National Health Service Hospital Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:
Favi E, Puliatti C, Ferraresso M, Cacciola R. Effect of Ethnicity on Recipient Characteristics, Kidney Transplant Provision and Outcomes in a High-Volume National Health Service Hospital [abstract]. https://atcmeetingabstracts.com/abstract/effect-of-ethnicity-on-recipient-characteristics-kidney-transplant-provision-and-outcomes-in-a-high-volume-national-health-service-hospital/. Accessed November 23, 2024.« Back to 2018 American Transplant Congress