Comparing Outcomes Between Technical Variant Liver Allografts and Whole Allografts in Pediatric Liver Transplantation: A Single Center's Experience.
1Surgery, Stanford University, Palo Alto, CA
2Intensive Care, Stanford University, Palo Alto, CA
3Anesthesia, Stanford University, Palo Alto, CA
Meeting: 2017 American Transplant Congress
Abstract number: B271
Keywords: Liver transplantation, Pediatric, Split-liver transplantation
Session Information
Session Name: Poster Session B: Pediatric Liver Transplant - Clinical
Session Type: Poster Session
Date: Sunday, April 30, 2017
Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall D1
Objective: To compare the outcome of technical variant liver transplants to whole allograft liver transplants in pediatric recipients.
Methods: A single center retrospective analysis of outcomes in pediatric recipients who received isolated liver transplants between 2010-2015. Specifically examined outcomes included magnitude of intraoperative transfusion expressed as percent of estimated blood volume (%EBV), rate of re-operation, rates of vascular and biliary complications, 1-year graft survival, and 1-year patient survival. Univariate statistical analysis included chi square to make comparisons between categorical variables. A P value of 0.05 was considered statistically significant.
Results: Data were available on 177 transplants in 170 patients ranging in age from 2 weeks to 21 years (5.0 years + 5.5). Patient weight varied from 2 to 88 kilograms. Sixty-four (36%) technical variant liver transplant were compared to 113 (64%) whole allograft transplants. There was no statistically significant difference in outcomes between the two groups.
| Outcomes | Whole Liver Transplant | Partial Liver Transplant | P-value |
| Re-operation | 15.7% | 22.2% | 0.27 |
| % EBV Transfused | 0.31%+0.4 | 0.46%+0.5 | 0.06 |
| Vascular Complications | 4.4% | 3.2% | 0.7 |
| Biliary Complications | 3.4% | 7.9% | 0.19 |
| 1-year Graft Survival | 92.2% | 95.2% | 0.41 |
| 1-year Patient Survival | 96.5% | 96.8% | 0.91 |
Conclusions: Technical variant allografts are not associated with increased surgical complications or decreased patient or graft survival in this single center's experience. Careful consideration of patient characteristics for use of the technical variant liver allograft is necessary to optimize outcomes but in an era of severe organ shortage technical variant livers can be safely utilized.
CITATION INFORMATION: Gallo A, Lee J, Damian M, Stoltz D, Bonham C, Esquivel C, Mendoza J. Comparing Outcomes Between Technical Variant Liver Allografts and Whole Allografts in Pediatric Liver Transplantation: A Single Center's Experience. Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:
Gallo A, Lee J, Damian M, Stoltz D, Bonham C, Esquivel C, Mendoza J. Comparing Outcomes Between Technical Variant Liver Allografts and Whole Allografts in Pediatric Liver Transplantation: A Single Center's Experience. [abstract]. Am J Transplant. 2017; 17 (suppl 3). https://atcmeetingabstracts.com/abstract/comparing-outcomes-between-technical-variant-liver-allografts-and-whole-allografts-in-pediatric-liver-transplantation-a-single-centers-experience/. Accessed November 21, 2024.« Back to 2017 American Transplant Congress